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The effects of pentoxifylline and tocopherol in jaw osteomyelitis

Seo MH, Eo MY, Myoung H, Kim SM, Lee JH

OBJECTIVES: Pentoxifylline (PTX) is a methylxanthine derivative that has been implicated in the pathogenesis of peripheral vessel disease and intermittent lameness. The purpose of this study was to investigate the...
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Differential Effects of Pentoxifylline on Learning and Memory Impairment Induced by Hypoxic-ischemic Brain Injury in Rats

Halis H, Bitiktaş , Baştuğ O, Tan B, Kavraal S, Güneş T, Süer C

OBJECTIVE: Hypoxic-ischemic (HI) brain injury in the human perinatal period often leads to significant long-term neurobehavioral dysfunction in the cognitive and sensory-motor domains. Using a neonatal HI injury model (unilateral...
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The effects of pentoxifylline adminstration on fracture healing in a postmenopausal osteoporotic rat model

Vashghani Farahani MM, Ahadi R, Abdollahifar M, Bayat M

Previous studies report positive effects of pentoxifylline (PTX) alone or in combination with other drugs on some pathologic bone diseases as well as an ability to accelerate osteogensis and fracture...
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Pentoxifylline Alleviates Perinatal Hypoxic-Ischemia-Induced Short-term Memory Impairment by Suppressing Apoptosis in the Hippocampus of Rat Pups

Park JH, Kim SE, Jin JJ, Choi HS, Kim CJ, Ko IG

PURPOSE: Perinatal hypoxic-ischemic brain damage is a major cause of acute mortality and chronic neurologic morbidity in infants and children. We investigated the effects of pentoxifylline, a methylxanthine derivative and...
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Effects of pentoxifylline administration on histomorphological parameters of streptozotocin-induced diabetic rat testes

Piryaei A, Najar A, Bayat M

The effect of pentoxifylline (PTX) administration on histomorphological parameters of streptozotocin (STZ)-induced type 1 diabetes mellitus (DM) in male rat testes were evaluated. We randomly divided 40 male rats into...
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The Effect of Pentoxifylline on Radiobiological Parameters in the Rat Radiation Myelopathy

Kim WD, Park WY

  • KMID: 2166052
  • Cancer Res Treat.
  • 2006 Dec;38(4):229-233.
PURPOSE: There is great recent interest in the potential value of using pentoxifylline (3,7-dimethyl-1(5-oxyhexyl)- xanthine, PTX) as an inhibitor of radiation-induced late normal tissue damage. The effects of PTX on...
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A Case of Pigmented Purpuric Lichenoid Dermatitis of Gougerot-Blum Treated by Pentoxifylline

Oh ST, Yoon SY, Lee SD, Park HJ, Lee JY, Cho BK

  • KMID: 2087056
  • Korean J Dermatol.
  • 2005 Nov;43(11):1544-1547.
The pigmented purpuric lichenoid dermatitis of Gougerot-Blum is a subtype of the pigmented purpuric dermatoses characterized by small red-brown lichenoid papules that coalesce to form plaque lesions. This disorder usually...
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Effect Of Pentoxifylline, Aspirin, And Heparin On Skin Flap Survival And Bleeding Tendency In Rabbits

Ha JW, Baek S, Park HJ, Oh HK, Ryu SY

  • KMID: 1577414
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2002 Sep;24(5):375-381.
The skin flap, which has been frequently used in the maxillofacial soft tissue defects, can be failed due to insufficient blood supply to the flap. To increase its survival rate,antithrombotic...
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Effect of Pentoxifylline on the ICSI Program Undergone in Severe Asthenozoospermia

Sohn JO, Shin JS, Jeong CJ, Cho YS, Oum KB, Choi DH, Kim HJ

  • KMID: 1864598
  • Korean J Fertil Steril.
  • 2002 Jun;29(2):97-103.
OBJECTIVE: The aim of this study was to evaluate the effect of Pentoxifylline(PF) on the conventional ICSI program undergone in severe asthenozoospermia. METHOD: Total 348 cycles of ICSI programs undertaken at...
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A Study of Preservation of Spinal Cord in Spinal Cord Ischemia of the Rabbit Comparison of Aprotinin and Pentoxifylline

Lee SY, Lee KR

  • KMID: 1941178
  • J Korean Soc Vasc Surg.
  • 2002 Apr;18(1):29-38.
PURPOSE: The complications of ischemic spinal cord injury on the descending and thoracoabdominal aorta remain a problem in spite of surgery and anesthesia advance. The protective effects of aprotinin and...
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Effect of Pentoxifylline on Liver Fibrosis and Cell Cycle Related Proteins in Thioacetamide-Induced Rat Cirrhosis

Jang KT, Lee MS, Jung IP, Kim MR, Jang JJ

  • KMID: 1890004
  • Korean J Hepatol.
  • 2001 Sep;7(3):281-291.
Background: Thioacetamide is a classic hepatotoxic reagent which leads to the reproducible hepatic fibrosis in rats. Thioacetamide-induced fibrosis is an appropriate model for cirrhosis in humans due to the long...
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Protective Effect of Pentoxifylline and Ciprofloxacin on Dimethylnitrosamine-induced Hepatic Fibrosis in Rats

Suh KS, Lee CH, Sol MY, Lee SK

  • KMID: 2241262
  • Korean J Hepatol.
  • 2001 Mar;7(1):34-46.
BACKGROUND/AIMS: Hepatic fibrosis is known to be a predisposing condition of cirrhosis for which there is no proven effective therapy. The aim of this study was to investigate the effect...
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Effect of Pentoxifylline on the Cerebral No-reflow Phenomenon after Cardiac Arrest in Rat

Choi KH, Oh DR, Lee WJ, Kim HK, Kim SK, Choi TH, Chae JS

  • KMID: 2194408
  • J Korean Soc Emerg Med.
  • 2000 Mar;11(1):1-10.
BACKGROUND: Successful resuscitation of the brain requires unimpaired blood recirculation. However, unfortunately there are several factors against the successful recirculation. No-reflow phenomenon, characterized by a lack of reperfusion after cerebral...
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Anti-inflammatory Effects of Pentoxifylline and Neutrophil Elastase Inhibitor on Lipopolysaccharide-Induced Acute Lung Injury In Vitro

Kim YK, Kim SJ, Park YK, Kim SC, Kim KH, Moon HS, Song JS, Park SH, Kim SH

BACKGROUND: Acute lung injury (ALI) is a commonly encountered respiratory disease and its prognosis is poor when the treatment is not provided promptly and properly. However no specific pharmacologic treatment...
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Modification of Late Radiation Response of Rat Salivary Glands by Pentoxifylline and Diltiazem

Suh HS, Yang KM, Kang YK

  • KMID: 1557168
  • J Korean Soc Ther Radiol Oncol.
  • 1999 Sep;17(3):230-237.
PURPOSE: To elucidate the effects of pentoxifylline and diltiazem on the late response of the salivary glands of the rat after irradiation. MATERIALS AND METHODS: Sixteen Sprague-Dawley rats were divided...
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Effect of Pentoxifylline on Ischemia-Reperfusion Injury of Brain Following Cardiac Arrest in Rats

Jeong SK, Park KN, Park SH, Oh DR, Lee WJ, Rue EY, Choi KH, Kim YM, Lee WJ, Kim SK

  • KMID: 2194554
  • J Korean Soc Emerg Med.
  • 1999 Jun;10(2):165-174.
BACKGROUND: Two major events occurring in the cerebral hemodynamics after successful resuscitation from cardiac arrest are reactive hyperemia and postischemic hypoperfusion. In this study, we examined the effect of Pentoxifylline(PTX)...
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The Effect of Pentoxifylline on IL-1beta and TNF-alpha mRNA Gene Expression in Hypoxic-Ischemic Brain Injury of Immature Rat

Kim KB, Jeon GH, Kim YR, Lee JH, Lee KH, Eun BL, Kim SK

  • KMID: 2007257
  • J Korean Child Neurol Soc.
  • 1999 Dec;7(2):181-187.
PURPOSE: Interleukin-1beta(IL-1beta) and Tumor necrosis factor-alpha(TNF-alpha) are multifunctional cytokines that may play important roles both in the normal development of central nervous system and in the response of brain to...
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Study on Therapeutic Effect of Pentoxifylline on Developmet of Multiple Organ Dysfuction Caused by Endotoxin in Rat

Lee GC, Jeong SS, Kim CK, Su DH, Lim HS, Kim CD, Hong KW

  • KMID: 2251439
  • Korean J Med.
  • 1998 May;54(5):587-597.
OBJECTIVES: Septic shock is characterized by the circulatory failure including vasodilation, hyporeactivity to vasoconstrictor agents and organ ischemia in association with multiple organ failure and increased platelet aggregation and blood...
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The Effect of Pentoxifylline on Rat Spinal Cord Damage to Fractionated Irradiation

Kim WD

  • KMID: 2175451
  • J Korean Cancer Assoc.
  • 1998 Feb;30(1):178-187.
No abstract available.
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Inhibitory Effects of Actinomycin-D and Pentoxifylline on the Production of IL-1alpha and TNF-alpha by Human Cord and Adult Blood Mononuclear Cells

Park EA, Kim KH, Kim GH

  • KMID: 2104452
  • J Korean Pediatr Soc.
  • 1998 Dec;41(12):1700-1708.
PURPOSE: An area of intense intrest is assessment of new therapeutic modalities that regulate the inflammatory response in acute bacterial infection is proving to be an area of interest these...
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