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The effects of pentoxifylline and tocopherol in jaw osteomyelitis

Seo MH, Eo MY, Myoung H, Kim SM, Lee JH

OBJECTIVES: Pentoxifylline (PTX) is a methylxanthine derivative that has been implicated in the pathogenesis of peripheral vessel disease and intermittent lameness. The purpose of this study was to investigate the...
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Differential Effects of Pentoxifylline on Learning and Memory Impairment Induced by Hypoxic-ischemic Brain Injury in Rats

Halis H, Bitiktaş , Baştuğ O, Tan B, Kavraal S, Güneş T, Süer C

OBJECTIVE: Hypoxic-ischemic (HI) brain injury in the human perinatal period often leads to significant long-term neurobehavioral dysfunction in the cognitive and sensory-motor domains. Using a neonatal HI injury model (unilateral...
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The effects of pentoxifylline adminstration on fracture healing in a postmenopausal osteoporotic rat model

Vashghani Farahani MM, Ahadi R, Abdollahifar M, Bayat M

Previous studies report positive effects of pentoxifylline (PTX) alone or in combination with other drugs on some pathologic bone diseases as well as an ability to accelerate osteogensis and fracture...
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Pentoxifylline Alleviates Perinatal Hypoxic-Ischemia-Induced Short-term Memory Impairment by Suppressing Apoptosis in the Hippocampus of Rat Pups

Park JH, Kim SE, Jin JJ, Choi HS, Kim CJ, Ko IG

PURPOSE: Perinatal hypoxic-ischemic brain damage is a major cause of acute mortality and chronic neurologic morbidity in infants and children. We investigated the effects of pentoxifylline, a methylxanthine derivative and...
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Managing alcoholic liver disease

Shah VH

Alcoholic liver disease continues to be a significant cause of liver-related morbidity and mortality throughout the world. A number of diagnostic and prognostic models have been developed in the management...
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Effects of pentoxifylline administration on histomorphological parameters of streptozotocin-induced diabetic rat testes

Piryaei A, Najar A, Bayat M

The effect of pentoxifylline (PTX) administration on histomorphological parameters of streptozotocin (STZ)-induced type 1 diabetes mellitus (DM) in male rat testes were evaluated. We randomly divided 40 male rats into...
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Clinical Analysis of Frostbite

Choi JK, Kim HC, Shin HK

PURPOSE: Frostbite can affect still soldiers. Initial clinical manifestations are similar for superficial and deep frostbite, so early treatment is identical. It is under-estimated by physicians. We try to identify...
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Characteristics and Clinical Manifestations of Pigmented Purpuric Dermatosis

Kim DH, Seo SH, Ahn HH, Kye YC, Choi JE

BACKGROUND: Pigmented purpuric dermatoses (PPD) are a spectrum of disorders characterized by a distinct purpuric rash. Although PPD can be easily diagnosed, the disease entity remains an enigma and a...
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Artificial oocyte activation in intracytoplasmic sperm injection cycles using testicular sperm in human in vitro fertilization

Kang HJ, Lee SH, Park YS, Lim CK, Ko DS, Yang KM, Park DW

OBJECTIVE: Artificial oocyte activation (AOA) is an effective method to avoid total fertilization failure in human in vitro fertilization-embryo transfer (IVF-ET) cycles. AOA performed using a calcium ionophore can induce...
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Diagnostic and Therapeutic Strategies for Severe Alcoholic Hepatitis

Kim W

Alcoholic hepatitis (AH) is defined as an acute hepatic manifestation resulting from heavy alcohol intake. Histologically, alcoholic steatohepatitis (ASH) is characterized by hepatocellular steatosis, inflammation, and fibrosis. Alcohol abstinence is...
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A Case of Generalized Pigmented Purpuric Dermatosis Treated with Narrowband Ultraviolet B Phototherapy in a Child

Na CH, Song SH, Kim MS, Shin BS

  • KMID: 2246250
  • Korean J Dermatol.
  • 2015 Jan;53(1):49-52.
Pigmented purpuric dermatosis (PPD) represents a group of cutaneous lesions exhibiting petechiae, pigmentation, and occasionally telangiectasia in the absence of an associated venous insufficiency or hematological disorder. PPD may resolve...
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Stereological Comparison of the Effects of Pentoxifylline, Captopril, Simvastatin, and Tamoxifen on Kidney and Bladder Structure After Partial Urethral Obstruction in Rats

Shirazi M, Soltani MR, Jahanabadi Z, Abdollahifar MA, Tanideh N, Noorafshan A

PURPOSE: Limited studies have shown antifibrotic effects of pentoxifylline, captopril, simvastatin, and tamoxifen. No comparisons are available of the effects of these drugs on prevention of renal and bladder changes...
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The renoprotective effects of pentoxifylline: beyond its role in diabetic nephropathy

Kapoor S

No abstract available.
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Evaluating the effects of pentoxifylline administration on experimental pressure sores in rats by biomechanical examinations

Velaei K, Bayat M, Torkman G, Rezaie F, Amini A, Noruzian M, Tavassol A, Bayat M

This study used a biomechanical test to evaluate the effects of pentoxifylline administration on the wound healing process of an experimental pressure sore induced in rats. Under general anesthesia and...
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Extensive Pigmented Purpuric Dermatosis Successfully Treated with Pentoxifylline

Mun JH, Jwa SW, Song M, Kim HS, Ko HC, Kim BS, Kim MB

No abstract available.
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Phosphodiesterase Inhibitor Improves Renal Tubulointerstitial Hypoxia of the Diabetic Rat Kidney

Sun HK, Lee YM, Han KH, Kim HS, Ahn SH, Han SY

BACKGROUND/AIMS: Renal hypoxia is involved in the pathogenesis of diabetic nephropathy. Pentoxifyllin (PTX), a nonselective phosphodiesterase inhibitor, is used to attenuate peripheral vascular diseases. To determine whether PTX can improve...
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Effect of Phosphodiesterase Inhibitor on Diabetic Nephropathy

Kang SW

No abstract available.
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Cilostazol Decreases Ethanol-Mediated TNFalpha Expression in RAW264.7 Murine Macrophage and in Liver from Binge Drinking Mice

Lee YJ, Eun JR

Alcoholic hepatitis is a leading cause of liver failure in which the increased production of tumor necrosis factor alpha (TNFalpha) plays a critical role in progression of alcoholic liver disease....
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Analysis of Frostbite (1)

Shin HK, Kim HC, Hong IK

  • KMID: 2329092
  • J Korean Burn Soc.
  • 2011 Dec;14(2):128-142.
PURPOSE: Frostbite can affect people involved in winter sports, homeless and soldiers. It results in tissue necrosis from direct cellular damage and indirect damage secondary to vasospasm and the progressive...
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A Case of Lichen Sclerosus et Atrophicus Accompanying Bullous Morphea

Yasar S, Mumcuoglu , Serdar ZA, Gunes P

Bullous morphea is a rare form of morphea characterized with bullae on or around atrophic morphea plaques. Whereas lichen sclerosus et atrophicus (LSA) is a disease the etiology of which...
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