- beta-Lapachone suppresses radiation-induced activation of nuclear factor-kappaB
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Dong GZ, Oh ET, Lee H, Park MT, Song CW, Park HJ
- KMID: 946632
- Exp Mol Med.
- 2010 May;42(5):327-334.
- doi: 10.3858/emm.2010.42.5.034
Anticancer effects of beta-lapachone (beta-lap) are due to generation of ROS and metabolic catastrophes as a result of NAD(P)H:quinone oxidoreductase (NQO1)-mediated futile cycling between the oxidized and reduced forms of... -
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- Enhancement of Radiosensitivity by DNA Hypomethylating Drugs through Apoptosis and Autophagy in Human Sarcoma Cells
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Park MT, Kim SD, Han YK, Hyun JW, Lee HJ, Yi JM
- KMID: 2524150
- Biomol Ther.
- 2022 Jan;30(1):80-89.
- doi: 10.4062/biomolther.2021.174
The targeting of DNA methylation in cancer using DNA hypomethylating drugs has been well known to sensitize cancer cells to chemotherapy and immunotherapy by affecting multiple pathways. Herein, we investigated... -
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