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A Patient with Neutropenia and Splenomegaly: A Case Report from Department of Family Medicine in Tertiary Hospital Center

Cho J, Song Y, Lee J, Lee D, Go Y, Kang HC

Pancytopenia represents a unique challenge for primary care doctors and its etiological causes encompass various specialties, including hematology and rheumatology. Despite the existence of effective tests such as bone marrow...
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A Case of Myelodysplastic Syndrome with Clinical Manifestations of Recurrent Cellulitis

Lim JH, Kim SM, Jee S, Park SO

An 84-year-old male patient with recurrent cellulitis in the left submandibular area visited the outpatient clinic. He underwent debridement of the wound with administration of intravenous antibiotics. The defect was...
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Evaluation of hematologic profile may be needed for patients treated with oxcarbazepine

Jung GH, You SJ

PURPOSE: The major side effects of treatment with oxcarbazepine (OXC) are skin rash and hyponatremia. Hematologic side effects are reported rarely. The aim of this study was to investigate the...
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Acute radiation syndrome in a non-destructive testing worker: a case report

Ahn JS, Moon JD, Kang W, Lim HM, Cho S, Lim DY, Park WJ

BACKGROUND: In Korea, there were repeated radiation exposure accidents among non-destructive testing workers. Most of the cases involved local injury, such as radiation burns or hematopoietic cancer. Herein, we report...
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A Case of Azathioprine Induced Severe Myelosuppression and Alopecia Totalis in IgA Nephropathy

Kim JC, Kim YK, Hyun HS, Park EJ, Kang HG, Ha IS, Cheong HI

Azathioprine is commonly used as immunosuppressive therapy for various inflammatory diseases including chronic glomerulonephritis. Myelosuppression is a common side effect of azathioprine, resulting in the need for dose reduction. However,...
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Two cases of incidental Podostroma cornu-damae poisoning

Kim HN, Do HH, Seo JS, Kim HY

Podostroma cornu-damae is a rare, deadly fungus. However, it can be easily mistaken for antler Ganoderma lucidum. In this case report, two patients made tea with the fungus and drank...
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A Case of Acute Myeloid Leukemia Developing after Treatment for Brucellosis with Pancytopenia

Kim SH, Kim KP, Han S, Kim YR, Kang SH

Human brucellosis is an important zoonotic disease and has a wide clinical spectrum. Nonspecific hematologic abnormalities related to brucellosis are frequently found, but pancytopenia is uncommon. Malignant diseases have been...
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Three Cases of Secondary Hemophagocytic Lymphohistiocytosis Associated with Systemic Erythematosus Lupus

Lim E, Kim YG, Choi WS, Jung YS, Han JH, Bae CB, Jung JY, Kim HA, Suh CH

Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder characterized by fever, pancytopenia, hyperferritinemia, and phagocytosis of hematopoietic cells in bone marrow, liver, or lymph nodes. HLH can occur during the course...
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A Case of Podostroma Cornu-Damae Intoxication Induced Pancytopenia and Skin Desquamation: Successful Treatment with Granulocyte Colony Stimulation Factor (G-CFS)

Kim JS, Kim GW, Chung JI, Sim MK, Yoon KC, Choi YH, Yi HR, Choi IZ, Shim CS, Han JH

  • KMID: 1846326
  • J Korean Soc Clin Toxicol.
  • 2015 Jun;13(1):50-54.
Podostroma cornu-damae is a rare species of fungus belonging to the Hyocreaceae family. Its fruit body is highly toxic, as it contains trichothecene mycotoxins. The morphology is similar to that...
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Polyglandular Autoimmune Syndrome Type 2 Complicated by Multiple Organ Failure, Empty Sella Syndrome and Aplastic Anemia

Kim HJ, Bae SI, Hong YH

Polyglandular autoimmune syndrome (PAS) is a group of syndromes comprised of glandular and extra-glandular disorders characterized by autoimmunity. A 57-year-old woman presented with acute progressive dyspnea and generalized weakness for...
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An Unusual Case of Severe Neonatal Lupus Mimicking Neonatal Sepsis and Literature Review

Park HM, Jun HG, Park JH, Choi SW, Oh KW, Oh JS

Neonatal lupus is an uncommon autoimmune disease that results from transplacental passage of the maternal anti-SSA/Ro and/or anti-SSB/La antibodies. Pancytopenia or severe jaundice is a rare manifestation of neonatal lupus,...
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Post-Hepatitic Aplastic Anemia Associated with Hepatitis A Virus

Jang JH, Jin YJ, Jang HI, Kim SI, Lee SN, Lee SH, Lee JW

Hepatitis-associated aplastic anemia is a rare disease, but can be fatal if it is diagnosed late or untreated. Despite the previous case report of severe aplastic anemia following hepatitis, hepatitis...
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Mushroom Poisoning by Podostroma cornu-damae: A Case Report and Review of the Literature

Yu HM, Kim J, Kang S, An S, Lim CH, Lee HG, Lee KR

  • KMID: 2333494
  • J Korean Soc Emerg Med.
  • 2013 Aug;24(4):469-472.
Podostroma cornu-damae is a rare species of fungus belonging to the Hyocreaceae family. Its fruit body is highly toxic, as it contains trichothecene mycotoxins. Unfortunately, it highly resembles Ganoderma lucidum...
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A Case of Pancytopenia with Hyperthyroidism

Kim TH, Yoon JS, Park BS, Lee DW, Cho JH, Moon JS, Kim EH, Won KC, Lee HW

  • KMID: 2320046
  • Yeungnam Univ J Med.
  • 2013 Jun;30(1):47-50.
There has been an increase in the number of reports of atypical manifestations of Graves' disease (GD), such as jaundice, anemia, thrombocytopenia and leukopenia. Pancytopenia also rarely occurs in GD....
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Two Cases of Mushroom Poisoning by Podostroma Cornu-Damae

Ahn JY, Seok SJ, Song JE, Choi JH, Han SH, Choi JY, Kim CO, Song YG, Kim JM

Podostroma cornu-damae is a rare fungus that houses a fatal toxin in its fruit body. In this case report, two patients collected and boiled the wild fungus in water, which...
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Histoplasmosis on bone marrow aspirate cytological examination associated with hemophagocytosis and pancytopenia in an AIDS patient

Chandra H, Chandra S, Sharma A

A 38-year-old woman who presented with unexplained fever and pancytopenia was subjected to a bone marrow examination. Her bone marrow aspirate smear showed no obvious pathological finding except for the...
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A Case of Sheehan's Syndrome with Pancytopenia

Lee HS, Kwon BW, Han JH, Kim HJ

Sheehan's syndrome is characterized by varying degrees of anterior pituitary dysfunction due to postpartum ischemic necrosis of the pituitary gland after massive bleeding. The spectrum of clinical presentation of Sheehan's...
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Pancytopenia Associated with Mycoplasma pneumoniae Pneumonia

Seo JH, Seo JH, Kim HY, Jung YH, Kim WS, Yu J, Hong SJ

  • KMID: 2315307
  • Pediatr Allergy Respir Dis.
  • 2012 Dec;22(4):417-421.
Mycoplasma pneumoniae is the most common pathogen of the respiratory tract among school-aged children and adolescents. It can also cause extrapulmonary manifestation that involves the skin, nervous system, digestive system,...
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Pancytopenia Associated with Hypopituitarism in an Acromegaly Patient: A Case Report and a Review of the Literature

Koh JH, Lee YJ, Kang JH, Choi BK, Jeon YK, Kim SS, Kim BH, Kim IJ

We present the case of a patient with acromegaly who had pancytopenia with hypopituitarism secondary to the excision of a pituitary macroadenoma and radiation therapy. A 28-year-old man presented with...
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Two Cases of Severe Pancytopenia Associated with Low-Dose Methotrexate Therapy in Patients with Chronic Kidney Disease and Rheumatoid Arthritis

Kim HI, Lee WH, Oh JS, Hong HR, Lee IH

  • KMID: 2320088
  • Yeungnam Univ J Med.
  • 2011 Jun;28(1):60-69.
Due to its efficacy and tolerability, low dose oral methotrexate(MTX) therapy has been widely used for treatment of rheumatoid arthritis(RA). However, it can rarely cause serious, life-threatening hematologic toxicities, such...
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