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Wound complication among different skin closure techniques in the emergency cesarean section: a randomized control trial

Nayak G B, Saha PK, Bagga R, Joshi B, Rohilla M, Gainder S, Sikka P

OBJECTIVE: Cesarean section is the most commonly performed obstetrical surgical procedure; however, there are no standard guidelines on appropriate skin closure techniques and materials. Only few comparative studies have been...
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Comparative evaluation of virtual reality distraction and counter-stimulation on dental anxiety and pain perception in children

Nunna M, Dasaraju R, Kamatham R, Mallineni , Nuvvula S

BACKGROUND: This study evaluated the efficacy of virtual reality (VR) distraction and counter-stimulation (CS) on dental anxiety and pain perception to local anesthesia in children. METHODS: A prospective, randomized, single-blinded interventional...
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Pain perception and efficacy of local analgesia using 2% lignocaine, buffered lignocaine, and 4% articaine in pediatric dental procedures

M.M A, Khatri A, Kalra N, Tyagi R, Khandelwal D

BACKGROUND: The purpose of this study was to compare the pain perception and anesthetic efficacy of 2% lignocaine with 1:200,000 epinephrine, buffered lignocaine, and 4% articaine with 1:200,000 epinephrine for...
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Masticatory muscle tenderness in burning mouth syndrome: A case control study

Yoon AH, Ryu JW

The aim of this study is to evaluate the masticatory muscle tenderness in burning mouth syndrome (BMS) patients. A total of 102 patients (48 with BMS and 54 with non-BMS)...
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Comparison of anxiety and pain perceived with conventional and computerized local anesthesia delivery systems for different stages of anesthesia delivery in maxillary and mandibular nerve blocks

Aggarwal K, Lamba AK, Faraz F, Tandon S, Makker K

BACKGROUND: Fear of local anesthesia (LA) is a significant impediment to dental care as many patients delay or avoid treatment to avert pain. Computer-controlled local anesthetic delivery system (CCLAD), with...
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Pain perception among patients treated with passive self-ligating fixed appliances and Invisalign® aligners during the first week of orthodontic treatment

Almasoud N

OBJECTIVE: This study was performed to compare the perception of pain between patients treated with passive self-ligating fixed appliances and those treated with Invisalign aligners. METHODS: This prospective study conducted in...
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Computerized intraligamental anesthesia in children: A review of clinical considerations

Baghlaf K, Elashiry E, Alamoudi N

Pain control by means of local anesthesia is an intrinsic part of clinical practice in dentistry. Several studies evaluated intraligamental anesthesia using a computer-controlled anesthetic device in children. There is...
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Orexin-A inhibits capsaicin-induced changes in cyclooxygenase-2 and brain-derived neurotrophic factor expression in trigeminal nucleus caudalis of rats

Kooshki R, Abbasnejad M, Esmaeili Mahani S, Raoof M, Moeini Aghtaei MM, Dabiri S

BACKGROUND: The trigeminal nucleus caudalis (Vc) is a primary central site for trigeminal transmitting. Noxious stimulation of the trigeminal nociceptors alters the central synaptic releases and neural expression of some...
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The Availability of Quantitative Assessment of Pain Perception in Patients With Diabetic Polyneuropathy

Park TJ, Kim SH, Lee HC, Chung SH, Kim JH, Park J

OBJECTIVE: To evaluate the usefulness of the quantitative assessment of pain perception (QAPP) in diabetic polyneuropathy (DPN) patients. METHODS: Thirty-two subjects with DPN were enrolled in this study. The subjects’ pain...
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Effect of a 5% naproxen patch on reducing pain caused by separators prior to fixed orthodontic treatment

Eslamian L, Akbarian Rad N, Rahbani Nobar B, Mortazavi

BACKGROUND: The pain involved in orthodontic treatments may involve inflammatory processes. This study evaluated the effect of using a naproxen patch for pain reduction in the separating stage of fixed...
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Depolarizing Effectors of Bradykinin Signaling in Nociceptor Excitation in Pain Perception

Choi SI, Hwang SW

Inflammation is one of the main causes of pathologic pain. Knowledge of the molecular links between inflammatory signals and pain-mediating neuronal signals is essential for understanding the mechanisms behind pain...
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Hemodynamic changes and pain perception-related anxiety after experiencing an impacted-tooth removal: clinical practice outcome

Raocharernporn S, Boonsiriseth K, Khanijou M, Wongsirichat N

BACKGROUND: Dental fear is usually associated with hemodynamic changes. Fear of pain during the surgical removal of a lower impacted third molar might cause patients anxiety, thereby leading to avoidance...
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Pulse-train Stimulation of Primary Somatosensory Cortex Blocks Pain Perception in Tail Clip Test

Lee S, Hwang E, Lee D, Choi JH

Human studies of brain stimulation have demonstrated modulatory effects on the perception of pain. However, whether the primary somatosensory cortical activity is associated with antinociceptive responses remains unknown. Therefore, we...
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The Effect of Intrarectal Lidocaine Gel Instillation before Transrectal Ultrasound Guided Prostate Biopsy

Kim YS, Kim SK, Choi K, Cho IC, Min SK

PURPOSE: To compare pain induced by a transrectal ultrasound (TRUS)-guided prostate biopsy in men between using local lidocaine gel or plain lubricant. MATERIALS AND METHODS: Between January and October of 2014,...
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The Role of Visceral Hypersensitivity in Irritable Bowel Syndrome: Pharmacological Targets and Novel Treatments

Farzaei MH, Bahramsoltani R, Abdollahi , Rahimi R

  • KMID: 2433449
  • J Neurogastroenterol Motil.
  • 2016 Oct;22(4):558-574.
  • doi: 10.5056/jnm16001
Irritable bowel syndrome (IBS) is the most common disorder referred to gastroenterologists and is characterized by altered bowel habits, abdominal pain, and bloating. Visceral hypersensitivity (VH) is a multifactorial process...
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Transplantation of adipose derived mesenchymal stem cells for acute thoracolumbar disc disease with no deep pain perception in dogs

Kim Y, Lee SH, Kim WH, Kweon OK

Thirty-four dogs with no deep pain perception due to acute thoracolumbar intervertebral disc disease underwent decompression surgery within 1 week of diagnosis. All dogs underwent hemilaminectomy. Adipose derived mesenchymal stem...
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Effects of EMLA Cream Application on Pain Perception and Pain Response of Children with Cancer During Implanted Venous Access Port Needle Insertion

Seo HY, Kim YH

PURPOSE: The purpose of this study was to identify effects of EMLA (Eutectic Mixture of Local Anesthetics) cream application on pain perception and pain response during insertion of implanted venous...
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Scrambler (Calmare) Therapy for Intractable Chronic Pain

Kim SA

Intractable chronic pain is a debilitative pain conditions for most patients. Unfortunately, the pain control managements currently have shown that it is not appropriate to reduce pain and limited efficacy...
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Protease-Activated Receptor-2 Is Associated with Terminal Differentiation of Epidermis and Eccrine Sweat Glands

Shin YS, Kim HW, Kim CD, Kim HW, Park JW, Jung S, Lee JH, Ko YK, Lee YH

BACKGROUND: Protease-activated receptor 2 (PAR-2) participates in various biological activities, including the regulation of epidermal barrier homeostasis, inflammation, pain perception, and melanosome transfer in the skin. OBJECTIVE: To evaluate the basic...
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Mechanical Antiallodynic Effect of Intrathecal Nefopam in a Rat Neuropathic Pain Model

Kim KH, Byeon GJ, Kim HY, Baek SH, Shin SW, Koo ST

Nefopam has a pharmacologic profile distinct from that of opioids or other anti-inflammatory drugs. Several recent studies demonstrate that nefopam has a mechanism of action similar to those of anti-depressants...
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