- Potent Potassium-competitive Acid Blockers: A New Era for the Treatment of Acid-related Diseases
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Oshima T, Miwa H
- KMID: 2517542
- J Neurogastroenterol Motil.
- 2021 Jul;27(3):443.
- doi: 10.5056/jnm18029A
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- Is a Patient With Asymptomatic Esophagitis Really Hyposensitive to Acid and Distention?
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Yamasaki T, Watari J, Oshima T, Tomita T, Miwa H
- KMID: 2325824
- J Neurogastroenterol Motil.
- 2011 Jul;17(3):318-319.
No abstract available. -
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- Epidemiology of Functional Gastrointestinal Disorders in Japan and in the World
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Oshima T, Miwa H
- KMID: 2433471
- J Neurogastroenterol Motil.
- 2015 Jul;21(3):320-329.
- doi: 10.5056/jnm14165
Functional gastrointestinal disorders (FGIDs), represented by functional dyspepsia (FD) and irritable bowel syndrome (IBS), are a group of disorders that include variable combinations of chronic or recurrent gastrointestinal symptoms not... -
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- Potent Potassium-competitive Acid Blockers: A New Era for the Treatment of Acid-related Diseases
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Oshima T, Miwa H
- KMID: 2417378
- J Neurogastroenterol Motil.
- 2018 Jul;24(3):334-344.
- doi: 10.5056/jnm18029
Conventional proton pump inhibitors (PPIs) are used as a first-line therapy to treat acid-related diseases worldwide. However, they have a number of limitations including slow onset of action, influence by... -
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- Preventing Metachronous Gastric Cancer after the Endoscopic Resection of Gastric Epithelial Neoplasia: Roles of Helicobacter pylori Eradication and Aspirin
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Watari J, Tomita T, Tozawa K, Oshima T, Fukui H, Miwa H
- KMID: 2500531
- Gut Liver.
- 2020 May;14(3):.
- doi: 10.5009/gnl19079
Whether Helicobacter pylori eradication actually reduces the risk of metachronous gastric cancer (MGC) development remains a controversial question. In this review, we addressed this topic by reviewing the results of... -
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- Esophageal Sensation and Esophageal Hypersensitivity: Overview From Bench to Bedside
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Miwa H, Kondo T, Oshima T, Fukui H, Tomita T, Watari J
- KMID: 2204231
- J Neurogastroenterol Motil.
- 2010 Oct;16(4):353-362.
Noxious stimuli in the esophagus activate nociceptive receptors on esophageal mucosa, such as transient receptor potential, acid-sensing ion channel and the P2X family, a family of ligand-gated ion channels responsive... -
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- Magnification Error in Digital Radiographs of the Cervical Spine Against Magnetic Resonance Imaging Measurements
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Shigematsu H, Koizumi M, Yoneda M, Iida J, Oshima T, Tanaka Y
- KMID: 2270406
- Asian Spine J.
- 2013 Dec;7(4):267-272.
- doi: 10.4184/asj.2013.7.4.267
STUDY DESIGN: Prospective study. PURPOSE: The main purpose of this study was to clarify the range of magnification errors on digital plain radiographs and to determine if there is a correlation... -
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- Prevalence and Self-recognition of Chronic Constipation: Results of an Internet Survey
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Tamura A, Tomita T, Oshima T, Toyoshima , Yamasaki T, Okugawa T, Kondo T, Kono T, Tozawa K, Ikehara H, Ohda Y, Fukui H, Watari J, Miwa H
- KMID: 2433461
- J Neurogastroenterol Motil.
- 2016 Oct;22(4):677-685.
- doi: 10.5056/jnm15187
BACKGROUND/AIMS: Although chronic constipation is a common symptom, to date no international consensus has been reached regarding its definition. The aims of this study were (1) to investigate defecation habits... -
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- Yokukansan Suppresses Gastric Hypersensitivity and Eosinophil-associated Microinflammation in Rats With Functional Dyspepsia
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Duan S, Imamura N, Kondo T, Kanda H, Kogure Y, Okugawa T, Fukushima M, Tomita T, Oshima T, Fukui H, Noguchi K, Dai Y, Miwa H
- KMID: 2528040
- J Neurogastroenterol Motil.
- 2022 Apr;28(2):255-264.
- doi: 10.5056/jnm21204
Background/Aims Herbal medicine is an important complementary therapy for functional dyspepsia (FD). However, its effect against gastric hypersensitivity in patients with FD has rarely been evaluated. Yokukansan (YKS), a traditional Japanese... -
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- Esophagography in Patients With Esophageal Achalasia Diagnosed With High-resolution Esophageal Manometry
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Yamasaki T, Tomita T, Mori S, Takimoto M, Tamura A, Hara K, Kondo T, Kono T, Tozawa K, Ohda Y, Oshima T, Fukui H, Watari J, Miwa H
- KMID: 2417384
- J Neurogastroenterol Motil.
- 2018 Jul;24(3):403-409.
- doi: 10.5056/jnm17147
BACKGROUND/AIMS: High-resolution esophageal manometry (HREM) is considered to be the gold standard for the diagnosis of achalasia. However, the Japan Esophageal Society recommends that esophagography is also accurate in either... -
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- Prevalence of Gastric Motility Disorders in Patients with Functional Dyspepsia
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Asano H, Tomita T, Nakamura K, Yamasaki T, Okugawa T, Kondo T, Kono T, Tozawa K, Ohda Y, Oshima T, Fukui H, Fukushima , Hirota S, Watari J, Miwa H
- KMID: 2387830
- J Neurogastroenterol Motil.
- 2017 Jul;23(3):392-399.
- doi: 10.5056/jnm16173
BACKGROUND/AIMS: Gastric motility abnormalities have been considered to be pathophysiological features of functional dyspepsia (FD) that are closely related to dyspepsia symptoms, especially postprandial distress syndrome (PDS). The aims of... -
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- Diarrhea-predominant Irritable Bowel Syndrome-like Symptoms in Patients With Quiescent Crohn’s Disease: Comprehensive Analysis of Clinical Features and Intestinal Environment Including the Gut Microbiome, Organic Acids, and Intestinal Permeability
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Tomita T, Fukui H, Morishita D, Maeda A, Makizaki Y, Tanaka Y, Ohno H, Oshima T, Miwa H
- KMID: 2537945
- J Neurogastroenterol Motil.
- 2023 Jan;29(1):102-112.
- doi: 10.5056/jnm22027
Background/Aims Diarrhea-predominant irritable bowel syndrome (IBS-D)-like symptoms frequently occur in patients with quiescent Crohn’s disease (CD). To investigate the factors underlying IBS-D-like symptoms in patients with quiescent CD, we performed a... -
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- Intravenous Corticotropin-releasing Hormone Administration Increases Esophageal Electrical Sensitivity in Healthy Individuals
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Yamasaki T, Tomita T, Takimoto M, Kondo T, Tozawa K, Ohda Y, Oshima T, Fukui H, Watari J, Miwa H
- KMID: 2395420
- J Neurogastroenterol Motil.
- 2017 Oct;23(4):526-532.
- doi: 10.5056/jnm17067
BACKGROUND/AIMS: When a person is experiencing stress, corticotropin-releasing hormone (CRH) can modulate gut physiologies, such as visceral sensation or gastrointestinal motility, and its intravenous administration mimics stress-induced physiological changes. However,... -
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- A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation
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Mori S, Tomita T, Fujimura K, Asano H, Ogawa T, Yamasaki T, Kondo T, Kono T, Tozawa K, Oshima T, Fukui H, Kimura T, Watari J, Miwa H
- KMID: 2460486
- J Neurogastroenterol Motil.
- 2019 Oct;25(4):563-575.
- doi: 10.5056/jnm18194
BACKGROUND/AIMS: Magnesium oxide (MgO) has been frequently used as a treatment for chronic constipation (CC) since the 1980s in Japan. The aim of this study is to evaluate its therapeutic... -
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- Prevalence of Irritable Bowel Syndrome–like Symptoms in Japanese Patients with Inactive Inflammatory Bowel Disease
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Tomita T, Kato Y, Takimoto M, Yamasaki T, Kondo T, Kono T, Tozawa K, Yokoyama Y, Ikehara H, Ohda Y, Oshima T, Fukui H, Tanaka S, Shima M, Watari J, Miwa H
- KMID: 2433459
- J Neurogastroenterol Motil.
- 2016 Oct;22(4):661-669.
- doi: 10.5056/jnm15160
BACKGROUND/AIMS: Few studies are available that have investigated the risk factors for overlapping irritable bowel syndrome (IBS)-like symptoms in patients with inactive inflammatory bowel disease (IBD). The present study has... -
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- Validity and Reliability of the Japanese Version of the Rome III Diagnostic Questionnaire for Irritable Bowel Syndrome and Functional Dyspepsia
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Kanazawa M, Nakajima S, Oshima T, Whitehead , Sperber AD, Palsson OS, Drossman D, Miwa H, Fukudo S
- KMID: 2381302
- J Neurogastroenterol Motil.
- 2015 Oct;21(4):537-544.
- doi: 10.5056/jnm15016
BACKGROUND/AIMS: Reliable diagnostic instruments for measuring the presence of functional gastrointestinal disorders based on the Rome III criteria have been lacking in Japan. The aims of the present study were... -
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- Knowledge, Attitude, and Practice Survey of Gastroparesis in Asia by Asian Neurogastroenterology and Motility Association
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Oshima T, Siah KTH, Kim YS, Patcharatrakul T, Chen CL, Mahadeva S, Park H, Chen MH, Lu CL, Hou X, Quach DT, Syam AF, Rahman MM, Xiao Y, Jinsong L, Chua ASB, Miwa H
- KMID: 2510061
- J Neurogastroenterol Motil.
- 2021 Jan;27(1):46-54.
- doi: 10.5056/jnm20117
Background/Aims Gastroparesis is identified as a subject that is understudied in Asia. The scientific committee of the Asian Neurogastroenterology and Motility Association performed a Knowledge, Attitude, and Practices survey on gastroparesis... -
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- The Practice of Gastrointestinal Motility Laboratory During COVID-19 Pandemic: Position Statements of the Asian Neurogastroenterology and Motility Association (ANMA-GML-COVID-19 Position Statements)
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Siah KTH, Rahman MM, Ong AML, Soh AYS, Lee YY, Xiao Y, Sachdeva S, Jung KW, Wang YP, Oshima T, Patcharatrakul T, Tseng PH, Goyal O, Pang J, Lai CKC, Park JH, Mahadeva S, Cho YK, Wu JCY, Ghoshal UC, Miwa H
- KMID: 2503998
- J Neurogastroenterol Motil.
- 2020 Jul;26(3):299-310.
- doi: 10.5056/jnm20107
During the Coronavirus Disease 2019 (COVID-19) pandemic, practices of gastrointestinal procedures within the digestive tract require special precautions due to the risk of contraction of severe acute respiratoy syndrome coronavirus-2... -
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- 2019 Seoul Consensus on Esophageal Achalasia Guidelines
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Jung HK, Hong SJ, Lee OY, Pandolfino J, Park H, Miwa H, Ghoshal UC, Mahadeva S, Oshima T, Chen M, Chua ASB, Cho YK, Lee TH, Min YW, Park CH, Kwon JG, Park MI, Jung K, Park JK, Jung KW, Lim HC, Jung DH, Kim DH, Lim CH, Moon HS, Park JH, Choi SC, Suzuki H, Patcharatrakul T, Wu JCY, Lee KJ, Tanaka S, Siah KTH, Park KS, Kim SE, The Korean Society of Neurogastroenterology and Motility
- KMID: 2500676
- J Neurogastroenterol Motil.
- 2020 Apr;26(2):180-203.
- doi: 10.5056/jnm20014
Esophageal achalasia is a primary motility disorder characterized by insufficient lower esophageal sphincter relaxation and loss of esophageal peristalsis. Achalasia is a chronic disease that causes progressive irreversible loss of... -
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- 2020 Seoul Consensus on the Diagnosis and Management of Gastroesophageal Reflux Disease
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Jung HK, Tae CH, Song KH, Kang SJ, Park JK, Gong EJ, Shin JE, Lim HC, Lee SK, Jung DH, Choi YJ, Seo SI, Kim JS, Lee JM, Kim BJ, Kang SH, Park CH, Choi SC, Kwon JG, Park KS, Park MI, Lee TH, Kim SY, Cho YS, Lee HH, Jung KW, Kim DH, Moon HS, Miwa H, Chen CL, Gonlachanvit S, Ghoshal UC, Wu JCY, Siah KTH, Hou X, Oshima T, Choi MY, Lee KJ, The Korean Society of Neurogastroenterology and Motility
- KMID: 2521147
- J Neurogastroenterol Motil.
- 2021 Oct;27(4):453-481.
- doi: 10.5056/jnm21077
Gastroesophageal reflux disease (GERD) is a condition in which gastric contents regurgitate into the esophagus or beyond, resulting in either troublesome symptoms or complications. GERD is heterogeneous in terms of... -
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