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Severe Ocular Hypertension in a Child with Pediatric Optic Neuritis

Yae CG, Oh JH, Kim DW, Chun BY

Purpose: To report a rare case of severe ocular hypertension following intravenous methylprednisolone treatment in a child with bilateral optic neuritis. Case summary: A 6-year-old girl presented with bilateral severe visual...
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Prognostic Factors for Visual Outcomes in Acute Anterior Optic Neuritis Using Optical Coherence Tomography

Park HY, Hong S, Kim S

Purpose: To identify the clinical characteristics and predictors of visual outcomes in acute anterior optic neuritis patients treated with high-dose steroid pulse therapy using spectral domain optical coherence tomography (SD-OCT). Methods:...
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Disease Course and Outcomes in Patients With the Limited Form of Neuromyelitis Optica Spectrum Disorders and Negative AQP4-IgG Serology at Disease Onset: A Prospective Cohort Study

Chen X, Zhou J, Li R, Zhang B, Wang Y, Zhong X, Shu Y, Chang Y, Qiu W

Background and Purpose Patients presenting with clinical characteristics that are strongly suggestive of neuromyelitis optica spectrum disorders (NMOSD) have a high risk of developing definite NMOSD in the future. Little...
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A Case of Neuromyelitis Optica Spectrum Disorder of a Patient Who Present for Fungal Sinusitis

Seo JW, Jeong DY, Kim H, Choi JY

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system, characterized by repeatedly invading the brain, optic nerve, or spinal cord. In 2004, when a disease-specific antibody...
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Choroidal Thickness in Multiple Sclerosis: An Optical Coherence Tomography Study

Masala A, Mola ID, Cellerino c M, Pera V, Vagge A, Uccelli A, Christian C, Traverso CE, Iester M

Background and Purpose To identify changes in the choroidal thickness (CT) in multiple sclerosis (MS) patients with and without optic neuritis (ON) using enhanced-depth-imaging optical coherence tomography (EDI-OCT). Methods This cross-sectional...
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Systemic Sarcoidosis Presenting as Bilateral Optic Neuritis

Rhyu JM, Kang JJ, Jeong MJ, Oh SY

Sarcoidosis is a multi-systemic inflammatory disease in which non-caseating granuloma occur in different sites producing variable clinical symptoms. Although it can involve various organs including brain and orbits, bilateral optic...
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Optic neuritis and multiple cranial neuropathies in patient with chronic inflammatory demyelinating polyneuropathy

Bae MJ, Lee J, Eun JI, Shin KJ

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a chronic recurrent acquired immune-mediated disease of the peripheral nerves that presents with progressive sensory and motor deficits in all four limbs. Cranial nerve...
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Atypical Multiple Sclerosis Presenting as Bilateral Optic Neuritis

Lee SY, Park MR

Purpose: We report a case of multiple sclerosis with bilateral optic neuritis that was atypical in terms of both the clinical signs and symptoms. Case summary: A 34-year-old female visited the...
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Idiopathic Chiasmal Optic Neuritis in a Pediatric Patient

Jeon JP, Lee D, Moon JW

Purpose: We report a case of idiopathic chiasmal optic neuritis in a pediatric patient. Case summary: A 13-year-old boy with no history of systemic disease was referred to our ophthalmology clinic...
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Comparison of Optic Neuritis with Seropositive Myelin Oligodendrocyte Glycoprotein Antibody and Seropositive Neuromyelitis Optica Antibody

Kang MC, Park KA

Purpose: To compare clinical outcomes of Korean patients with seropositive myelin oligodendrocyte glycoprotein antibody (MOG-IgG)-related optic neuritis (ON) and those with neuromyelitis optica antibody (NMO-IgG)-related ON. Methods: Medical records were analyzed...
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A Case of Visual Loss Caused by Invasive Fungal Sinusitis of the Onodi Cell

Gim TW, Yoo SC, Lee SY, Jeong JI

Invasive fungal sinusitis is common in immunodeficiency patients and can spread into the orbit or intracranial cavity. The Onodi cell, which is one of the anatomical variations of the ethmoid...
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Neuromyelitis Optica Spectrum Disorders Mimicking Multiple Brain Tumors

Park SH, Hwang JH

We report a rare case of neuromyelitis optica spectrum disorders (NMOSD), mimicking multiple brain tumors. A 53-year-old woman presented with weakness and paresthesia in her right arm and leg. Upon...
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Myelin oligodendrocyte glycoprotein antibody-associated disorders: clinical spectrum, diagnostic evaluation, and treatment options

Lee YJ, Nam SO, Ko A, Kong J, Byun SY

Inflammatory or immune-mediated demyelinating central nervous system (CNS) syndromes include a broad spectrum of clinical phenotype and different overlapping diseases. Antibodies against myelin oligodendrocyte glycoprotein (MOG-Ab) have been found in...
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Antineutrophil Cytoplasmic Antibody-associated Optic Neuritis

Lee J, Baek J

Purpose: We report a case of antineutrophil cytoplasmic antibody (ANCA)-associated optic neuritis with glomerulonephritis. Case summary: A 66-year-old male with a history of acute kidney injury presented with decreased visual acuity...
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A Case of 40-Year-Old Male with Onodi Cell Mucocele

Cho SD, Kang SH, Seo Y, Kim HJ

Sphenoethmoidal (Onodi) cells originate from the ethmoid sinus and are located at the posterior and lateral direction. The obstruction of the sinus ostium leads to the accumulation of mucous fluid...
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A Comparison of Retinal Thickness Changes According to Initial Optic Disc Edema in Optic Neuritis Patients

Kim DS, Hong EH, Shin YU, Kang MH, Seong M, Cho HY

Purpose: To compare early changes in the macular retinal nerve fiber layer (mRNFL) and ganglion cell-inner plexiform layer (mGCIPL) thicknesses according to the severity of initial optic disc edema in...
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Relapse of Neuromyelitis Optica Spectrum Disorder Presented with Suspected Bacterial Meningomyelitis

Kim GS, Kim BY, Song P, Lee JJ, Park HK, Park HR, Cho JY

Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory demyelinating disease. Anti-aquaporin-4 antibodies serve as a specific biomarker, while other factors including antecedent infection may also play a role in...
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Recurrent Optic Neuritis and Acute Encephalopathy with Myelin Oligodendrocyte Glycoprotein Antibodies in a Korean Child

Hwang JE, Kim SH, Park S

Myelin oligodendrocyte glycoprotein (MOG) antibody-associated diseases are reported to have distinct pathogenic mechanisms, clinical courses, and therapeutic implications in comparison to other acquired demyelinating syndromes. Here, we report the case...
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Long-term follow-up of optic neuritis associated with meningoencephalitis of unknown etiology in a Maltese dog

Jung SJ, Kim J, Plummer CE, Lee KC, Kim MS

A 6-year-old intact male Maltese dog presented with a history of blindness and ataxia. Neuro-ophthalmic examination revealed dilated pupils with absent pupillary light reflexes and menace response in both eyes....
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Optic Neuritis Accompanied by Optic Perineuritis after Peribulbar Retinalamin Injection

Lee GM, Ha SJ

PURPOSE: To report a case of optic neuritis accompanied by optic perineuritis after retinalamin peribulbar injection. CASE SUMMARY: A 46-year-old Kazakhstan woman presented with sudden vision loss, headache, and pain in...
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