- A Case of Leber Hereditary Optic Neuropathy Showing Optic Disc Hyperfluorescence
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Park YJ, Lim HT
- KMID: 2431847
- J Korean Ophthalmol Soc.
- 2019 Jan;60(1):96-101.
- doi: 10.3341/jkos.2019.60.1.96
PURPOSE: We report an unusual case of Leber hereditary optic neuropathy presenting with optic disc hyperfluorescence. CASE SUMMARY: A 17-year-old male with sequential painless visual loss 3 weeks apart affecting first... -
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- A Case of Atypical Leber Hereditary Optic Neuropathy Associated with MT-TL1 Gene Mutation Misdiagnosed with Glaucoma
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Hahn IK, Lim HT
- KMID: 2367853
- J Korean Ophthalmol Soc.
- 2017 Jan;58(1):117-123.
- doi: 10.3341/jkos.2017.58.1.117
PURPOSE: Leber hereditary optic neuropathy (LHON) is one of the most common hereditary optic neuropathies caused by mutations of mitochondrial DNA. Three common mitochondrial mutations causing LHON are m.3460, m.11778,... -
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- Leber's Hereditary Optic Neuropathy with Mitochondrial DNA 11778 Mutation Presenting with Various Types of Seizures
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Kim KS, Moon JS, Lee JH, Ha SW, Kang SJ, Kim MJ, Kim JK, Yoo BG
- KMID: 2065616
- J Korean Neurol Assoc.
- 2006 Oct;24(5):498-502.
Leber's hereditary optic neuropathy (LHON) is a mitochondrial genetic disease characterized by acute or subacute visual loss associated with other neurologic diseases. We report a man with LHON caused by... -
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- Mitochondrial DNA Content and the MTND4 Gene Expression in Leber's Hereditary Optic Neuropathy
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Seong MW, Kim JY, Ko HS, Hwang JM, Park SS
- KMID: 2143217
- Korean J Lab Med.
- 2004 Dec;24(6):439-445.
BACKGROUND: Leber's hereditary optic neuropathy (LHON) is characterized by acute or subacute bilateral visual loss, primarily caused by a mitochondrial DNA (mtDNA) point mutation. However the pathogenic mechanism of visual... -
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- Ondine's Curse Consequent to Recurrent Respiratory Failure in a Man with Leber Hereditary Optic Neuropathy
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Ha S, An SG, Lee SA
- KMID: 2343097
- J Korean Neurol Assoc.
- 2004 Aug;22(4):414-417.
Leber's hereditary optic neuropathy (LHON) is a disease due to mitochondrial DNA mutations. We report a man with LHON, who presented with four episodes of respiratory failure. In the last... -
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- Molecular Genetic Study on Primary and Secondary Mitochondrial DNA Mutations of Leber's Hereditary Optic Neuropathy in Koreans
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Hwang JM, Kim JY, Ko HS, Park SS, Chang BL
- KMID: 2022104
- J Korean Ophthalmol Soc.
- 2003 May;44(5):1153-1158.
PURPOSE: In order to evaluate the spectrum of mitochondrial DNA (mtDNA) mutations in the patients with suspected Leber's hereditary optic neuropathy (LHON). METHODS: We investigated 14 primary mtDNA mutations at... -
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- Leber's Hereditary Optic Neuropathy with Dystonia Caused by mtDNA 11778 Mutation
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Choi EJ, Lee SA, Ha JH, Ahn HS
- KMID: 2186058
- J Korean Neurol Assoc.
- 2000 Mar;18(2):244-248.
Several mtDNA mutations have been reported in Leber's hereditary optic neuropathy (LHON) associated with dystonia since it was identified as having the 14459 mutation. We report a patient with LHON... -
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- Optic Neuropathy in Koreans I. Leber's Hereditary Optic Neuropathy
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Kim SJ, Hwang JM, Chang BL, Park SS, Shin S, Yoon KY, Jung YC
- KMID: 2336720
- J Korean Ophthalmol Soc.
- 1998 Sep;39(9):2152-2159.
No abstract available. -
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- Clinical Manifestations of Leber's Hereditary Optic Neuropathy with 11778 mtDNA Mutation
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Kim SJ, Hwang JM, Park HW
- KMID: 2123512
- J Korean Ophthalmol Soc.
- 1996 Aug;37(8):1389-1396.
Leber's hereditary optic neuropathy is caused by a single nucleotide change in the mitochondrial deoxynucleic acid(mtDNA) and accounts for 30% of bilateral optic atrophy of unknown etiology. The authors found... -
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- A Mitochondrial Mutation in Leber's Hereditary Optic Neuropathy
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Hwang JM, Park HW
- KMID: 2205183
- J Korean Ophthalmol Soc.
- 1995 Dec;36(12):2218-2224.
Leber's hereditary optic neuropathy is caused by a single nucleotide change in the mitochondrial deoxynucleic acid(mtDNA). We identified a single guanine to adenine transition mutation in the mitochondrial DNA at... -
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- Leber's Hereditary Optic Neuropathy in Two Brothers of a Family
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Hur J, Sohn HY, Won IG
- KMID: 2122947
- J Korean Ophthalmol Soc.
- 1990 Feb;31(2):241-248.
The Leber's hereditary optic neuropathy, which affects mainly males in the late teens or in the early twenties, is a rare inherited disorder characterized by bilateral rapid loss of central... -
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- Two Cases of Leber's Hereditary Optic Atrophy Occurred in Mother and Son
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Park BG, Kim KS
- KMID: 2204736
- J Korean Ophthalmol Soc.
- 1982 Sep;23(3):867-871.
Leber's hereditary optic atrophy is characterized by sudden loss of central vision occuringin the second and third decade of life and nondirect transmission with male preponderance, Leber disease affecting both... -
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- Three Cases of Leber's Hereditary Optic Atrophy in One Family
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Park JC, Lee JH, Chang WU
- KMID: 1665776
- J Korean Ophthalmol Soc.
- 1980 Sep;21(3):361-365.
The authors have experienced with three cases of Leber's hereditary optic atrophy one family which is a relatively rare condition characterized by acute or subacute failrure of central vision presenting... -
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