- Comparison of young male mice of two different strains (C57BL/6J and the hybrid B6129SF1/J) in selected behavior tests: a small scale study
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Aasland Hansen K, Hudecová A, Haugen F, Skjerve E, Ropstad E, Zimmer K
- KMID: 2537631
- Lab Anim Res.
- 2022 Dec;38(4):287-293.
- doi: 10.1186/s42826-022-00140-5
Background: All mouse strains are different, before choosing a strain for a large study, a small scale study should be done. In this study, we compared young males of two... -
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- Influences of Dopamine D2, D3 Agonist Quinpirole Dosage on Locomotor Activity Measured by Open-Field Test
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Park J, Moon E, Lim HJ, Kim K, Lee JH, Hong YR
- KMID: 2538400
- Mood Emot.
- 2022 Nov;20(3):59-64.
- doi: 10.35986/me.2022.20.3.59
Background: Dopamine D2 and D3 receptor agonist quinpirole have been tried as one of drug-induced bipolar animal models. An open-field test is used to assess locomotor activity related to anxiety.... -
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- Ketamine-Induced Behavioral Effects Across Different Sub-AnestheticDose Ranges in Adolescent and Adult Mice
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Choi HJ, Im SJ, Park HR, Lee SM, Kim CE, Ryu S
- KMID: 2500129
- Korean J Biol Psychiatry.
- 2020 Apr;27(1):27-35.
- doi: 10.22857/kjbp.2020.27.1.004
ObjectivesZZKetamine has been reported to have antidepressant effects or psychotomimetic effects. The aim of this study was to investigate the behavioral effects of ketamine treatment at various sub-anesthetic doses in adolescent... -
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- Protein Kinase C Activity and Delayed Recovery of Sleep-Wake Cycle in Mouse Model of Bipolar Disorder
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Moon E, Choe BM, Park JM, Chung YI, Lee BD, Park JH, Lee YM, Jeong HJ, Cheon Y, Choi Y, Park J
- KMID: 2424024
- Psychiatry Investig.
- 2018 Sep;15(9):907-913.
- doi: 10.30773/pi.2018.05.23
OBJECTIVE: Previous studies reported the delayed recovery group after circadian rhythm disruption in mice showed higher quinpiroleinduced locomotor activity. This study aimed to compare not only Protein Kinase C (PKC)... -
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- Reliability and validity of free software for the analysis of locomotor activity in mice
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Hong YR, Moon E
- KMID: 2415735
- Yeungnam Univ J Med.
- 2018 Jun;35(1):63-69.
- doi: 10.12701/yujm.2018.35.1.63
BACKGROUND: Kinovea software that tracking semi-automatically the motion in video screen has been used to study motion-related tasks in several studies. However, the validation of this software in open field... -
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- Delay in Normalization of Disrupted Sleep-Wake Cycle in Mice as a Bipolar Disorder-Prone Animal Model (Bipolar Disorder-Prone Animal Model)
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Kim SY, Moon E, Jeong HJ, Lee YM, Lee BD, Park JM
- KMID: 2351547
- J Korean Neuropsychiatr Assoc.
- 2016 Aug;55(3):209-214.
- doi: 10.4306/jknpa.2016.55.3.209
OBJECTIVES: This study was designed to test the hypothesis that delayed recovery from disrupted circadian rhythm is associated with both manic and depressive episodes in bipolar disorder. METHODS: Twenty-two male mice... -
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- Delay in the Recovery of Normal Sleep-Wake Cycle after Disruption of the Light-Dark Cycle in Mice: A Bipolar Disorder-Prone Animal Model?
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Jung SH, Park JM, Moon E, Chung YI, Lee BD, Lee YM, Kim JH, Kim SY, Jeong HJ
- KMID: 2316378
- Psychiatry Investig.
- 2014 Oct;11(4):487-491.
- doi: 10.4306/pi.2014.11.4.487
OBJECTIVE: Disruption of the circadian rhythm is known as a provoking factor for manic episodes. Individual differences exist in the recovery rate from disruption in the general population. To develop... -
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- Chronic Administration of Bacopa Monniera Increases BDNF Protein and mRNA Expressions: A Study in Chronic Unpredictable Stress Induced Animal Model of Depression
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Banerjee R, Hazra S, Ghosh AK, Mondal AC
- KMID: 2316351
- Psychiatry Investig.
- 2014 Jul;11(3):297-306.
OBJECTIVE: The present study aimed to investigate whether graded doses of Bacopa Monniera (BM) extract could produce antidepressant-like effects in chronic unpredictable stress (CUS) induced depression in rats and its... -
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- Chronic Non-Social Stress Affects Depressive Behaviors But Not Anxiety in Mice
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Yoon SH, Kim BH, Ye SK, Kim MH
- KMID: 2285519
- Korean J Physiol Pharmacol.
- 2014 Jun;18(3):263-268.
- doi: 10.4196/kjpp.2014.18.3.263
The etiology of most psychiatric disorders is still incompletely understood. However, growing evidence suggests that stress is a potent environmental risk factor for depression and anxiety. In rodents, various stress... -
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- Chronic Administration of Monosodium Glutamate under Chronic Variable Stress Impaired Hypothalamic-Pituitary-Adrenal Axis Function in Rats
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Seo HJ, Ham HD, Jin HY, Lee WH, Hwang HS, Park SA, Kim YS, Choi SC, Lee S, Oh KJ, Kim BS, Park BR, Lee MY
- KMID: 2285405
- Korean J Physiol Pharmacol.
- 2010 Aug;14(4):213-221.
- doi: 10.4196/kjpp.2010.14.4.213
The hypothalamic-pituitary-adrenal (HPA) axis is the primary endocrine system to respond to stress. The HPA axis may be affected by increased level of corticotrophin-releasing factors under chronic stress and by... -
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- Social Isolation Selectively Increases Anxiety in Mice without Affecting Depression-like Behavior
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Kwak C, Lee SH, Kaang BK
- KMID: 1982568
- Korean J Physiol Pharmacol.
- 2009 Oct;13(5):357-360.
- doi: 10.4196/kjpp.2009.13.5.357
It is hypothesized that a number of environmental factors affect animals' behavior. Without controlling these variables, it is very hard for researchers to get not only reliable, but replicable data... -
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- Behamioral Change and Memory Inpairment Following Transient Forebrain Ischemia in Rats
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Rho CK, Kwon JY, Kim HK, Baik SW, Kim IS, Chung KS
- KMID: 2237088
- Korean J Anesthesiol.
- 1991 Oct;24(5):925-930.
- doi: 10.4097/kjae.1991.24.5.925
This study examined the behavioral change and memory impairment following transient forebrain ischemia in 20 male rats: ten rats were subjected to sham operation. Inchemia was induced by a combination... -
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