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Perspectives in TSPO PET Imaging for Neurologic Diseases

Song YS

The translocator protein (18 kDa) (TSPO) is a mitochondrial transmembrane protein, which has brought attention as a neuroinflammatory biomarker. Positron emission tomography (PET) imaging studies have been done for several...
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Radioimmunotherapy (RIT) in Brain Tumors

Gholamrezanezhad A, Shooli H, Jokar N, Nemati R, Assadi M

Annually, the incidence of brain tumors has slightly increased and also the patient prognosis is still disappointing, especially for high-grade neoplasms. So, researchers seek methods to improve therapeutic index as...
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68Ga-PSMA: a One-stop Shop in Radioactive Iodine Refractory Thyroid Cancer?

Lengana T, Lawal IO, Mokoala K, Vorster M, Sathekge M

We report a case of a 47-year-old female known with metastatic papillary thyroid cancer. Her treatment history included total thyroidectomy and 3 previous radio ablations with a cumulative dose of...
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Intramastoid Phosphaturic Mesenchymal Tumor Causing Hypophosphatemic Osteomalacia Detected on ⁶⁸Ga-DOTATATE PET/CT But Not on (99m)Tc-Sestamibi and ¹⁸F-FDG Scans

Araujo CS, Seguro LP, Duarte PS, Buchpiguel CA, Pereira RM

⁶⁸Ga-DOTATATE uptake in mesenchymal tumors causing hypophosphatemic osteomalacia has been recently described. Herein, we present a case of ⁶⁸Ga-DOTATATE uptake in an intramastoid phosphaturic mesenchymal tumor that had not been...
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Radioembolization for the Treatment of Primary and Metastatic Liver Cancers

Lee EJ, Chung HW, Jo JH, So Y

Radioembolization using ⁹⁰Y microspheres (glass or resin) has been introduced as an effective intraarterial therapy for unresectable primary and metastatic liver cancers. Although the basic therapeutic effect of chemoembolization results...
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Effect of ME Collimator Characteristic, Energy Window Width, and Reconstruction Algorithm Selection on Imaging Performance of Yttrium-90: Simulation Study

Taherparvar P, Shahmari N

PURPOSE: The treatment efficiency of ⁹⁰Y and providing reliable estimates of activity are evaluated by SPECT imaging of bremsstrahlung radiation released during beta therapy. In this technique, the resulting spectrum...
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Comparative Analysis of Lung Perfusion Scan and SPECT/CT for the Evaluation of Functional Lung Capacity

Suh HY, Park S, Ryoo HG, Kim JY, Kim TS, Lee JM, Kim MS, Yang HC, Kim SK

PURPOSE: This study aimed to compare lung perfusion scan with single photon emission computed tomography/computed tomography (SPECT/CT) for the evaluation of lung function and to elucidate the most appropriate modality...
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Orbital IgG4 Disease: Imaging Findings on 68Ga-DOTANOC PET/CT

Arora S, Damle NA, Meel R, Sharma S, Sen S, Bal C, Lata K, Prakash S, Yadav D, Angamuthu

Immunoglobulin G4 (IgG4)–related diseases are a spectrum of systemic inflammatory conditions of unknown etiology, which are characterized by infiltration of tissues by IgG4 plasma cells and sclerosing inflammation (Cheuk and...
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Prognostic Value of Metabolic Information in Advanced Gastric Cancer Using Preoperative ¹⁸F-FDG PET/CT

Kwon HR, Pahk K, Park S, Kwon HW, Kim S

PURPOSE: This study evaluated the usefulness of semiquantitative and volumetric PET parameters for predicting prognosis in patients with advanced gastric cancer (AGC). METHODS: We enrolled 213 patients who underwent ¹⁸F-fluoro-2-deoxyglucose positron...
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Safety Profile and Therapeutic Efficacy of One Cycle of Lu177-PSMA in End-Stage Metastatic Castration-Resistant Prostate Cancer Patients with Low Performance Status

Gupta M, Choudhury , Rawal S, Karthikeyan G, Talwar V, Dutta KD, Singh A

PURPOSE: The aim of this study was to evaluate safety and therapeutic efficacy of lutetium 177 prostate-specific membrane antigen (Lu-177-PSMA) in metastatic castration-resistant prostate cancer (mCRPC) patients with low performance...
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Reverse Warburg Effect-Related Mitochondrial Activity and ¹⁸F-FDG Uptake in Invasive Ductal Carcinoma

Choi BW, Jeong YJ, Park SH, Oh HK, Kang S

PURPOSE: We evaluated the relationship between fluorine-18 fluoro-2-deoxy-glucose (¹⁸F-FDG) uptake and mitochondrial activity in cancer cells and investigated the prognostic implications of this relationship in patients with invasive ductal carcinoma...
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