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Flavonoids Modulate the Proliferation of Neospora caninum in Glial Cell Primary Cultures

Barbosa de Matos R, Braga-de-Souza S, Pena Seara Pitanga B, Amaral da Silva VD, Viana de Jesus EE, Morales Pinheiro A, Dias Costa MdF, dos Santos El-Bacha R, de Oliveira Ribeiro CS, Lima Costa S

Neospora caninum (Apicomplexa; Sarcocystidae) is a protozoan that causes abortion in cattle, horses, sheep, and dogs as well as neurological and dermatological diseases in dogs. In the central nervous system...
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H2 Receptor-Mediated Relaxation of Circular Smooth Muscle in Human Gastric Corpus: the Role of Nitric Oxide (NO)

Lee SE, Kim DH, Kim YC, Han JH, Choi W, Kim CH, Jeong HW, Park SM, Yun SJ, Choi SY, Sung R, Kim YH, Yoo RY, Sun PH, Kim H, Song YJ, Xu WX, Yun HY, Lee SJ

This study was designed to examine the effects of histamine on gastric motility and its specific receptor in the circular smooth muscle of the human gastric corpus. Histamine mainly produced...
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Nitric Oxide-mediated Relaxation by High K+ in Human Gastric Longitudinal Smooth Muscle

Kim YC, Choi W, Yun HY, Sung R, Yoo RY, Park SM, Yun SJ, Kim MJ, Song YJ, Xu WX, Lee SJ

This study was designed to elucidate high-K+induced response of circular and longitudinal smooth muscle from human gastric corpus using isometric contraction. Contraction from circular and longitudinal muscle stripes of gastric...
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The effect of heat shock protein 70 on inducible nitric oxide synthase during sepsis in rats

Lee YK, Ahn Y, Leem DH, Baek JA, Ko SO, Shin HK

  • KMID: 2328498
  • J Korean Assoc Oral Maxillofac Surg.
  • 2010 Oct;36(5):346-352.
INTRODUCTION: Heat shock protein70 (HSP70) is a highly conserved family of proteins produced after a variety of stresses. Many studies reported that the overexpression of HSP70 can improve the prognosis...
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Flowers of Inula japonica Attenuate Inflammatory Responses

Choi JH, Park YN, Li Y, Jin MH, Lee J, Lee Y, Son JK, Chang HW, Lee E

BACKGROUND: The flowers of Inula japonica (Inulae Flos) have long been used in traditional medicine for the treatment of inflammatory diseases. In the present study, we investigated the anti-inflammatory properties...
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Anti-Inflammatory Effect of Near-Infrared Irradiated Cell Culture Media

Kim SG, Shin IH, Choi CH, Choe JY

BACKGROUND: Near-infrared light (NIR, 0.8-1.5 micrometer light) has been used in therapeutic devices for various injuries such as infected, ischemic and hypoxic wound. NIR-emitting technology has been developed recently in...
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Effects of NOS Inhibitors on Arthritis and Arthritic Pain in Rats

Min SS

  • KMID: 1512890
  • Korean J Physiol Pharmacol.
  • 2007 Dec;11(6):253-257.
Among the arthritis symptoms, chronic pain is the most serious, and it can profoundly affect the quality of human life. Unfortunately, the mechanism of development in arthritis and arthritic pain...
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Measurements of Exhaled Nitric Oxide in Newborns

Kim SK, Rha YH, Bae CW

  • KMID: 2144519
  • J Korean Soc Neonatol.
  • 2007 May;14(1):39-45.
PURPOSE: Exhaled nitric oxide (eNO) is a reliable marker of eosinophilic airway inflammation in asthma. But few studies have measured endogenous nitric oxide exhaled from the respiratory system of newborns....
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Effects of Prenatal Exposure to Nitric Oxide Synthase Inhibitor on MK-801-Elicited Behavioral Sensitivity in Postnatal Rats

Park SH, Kim GJ, Chung YI

  • KMID: 2341261
  • J Korean Neuropsychiatr Assoc.
  • 2007 Jan;46(1):13-18.
OBJECTIVES: The aim of the present study was to investigate the role of prenatal exposure to NOS (nitric oxide synthase) inhibitor during the 3rd trimester of pregnancy on MK-801-elicited behavioral...
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The Effects of air-borne particulate matters on the Alveolar Macrophages for the iNOS Expression and Nitric Oxide with Nitrotyrosilated-proteins Formation

Cui FJ, Li TZ, Lee SJ, Park SJ, Lim Y, Kim KA, Chang BJ, Lee JH, Lee MH, Choe NH

BACKGROUND: Particulate matters (PM) when inhaled is known to induce pulmonary diseases including asthma and chronic bronchitis when inhaled. Despite the epidemiological proofevidence, the pathogenesis of PM-related pulmonary diseases is...
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Inhibitory Effect of Inducible Nitric Oxide Synthase Gene Transfer on Intimal Hyperplasia and Fibronectin Expression Induced by Carotid Artery Denudation

Kye BH, Hong SY, Yang KH, Park SC, Park JS

  • KMID: 1941030
  • J Korean Soc Vasc Surg.
  • 2004 Dec;20(2):192-199.
PURPOSE: Intimal hyperplasia is a pathologic condition that is commonly observed with the atherosclerotic change of blood vessels; this condition is usually observed after arterial operation and interventions such as...
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Apoptosis and Peripheral Benzodiazepin Receptor (PBR) Expression in Human Granulosa-Luteal Cells by GnRH-agonist

Kim SK, Youm YH, Yoon JM, Bai SW, Yang H, Cho DJ, Yoon YD, Song CH

  • KMID: 1573855
  • Korean J Fertil Steril.
  • 2004 Jun;31(2):83-94.
OBJECTIVE: To investigate whether GnRH-agonist (GnRH-Ag) using in IVF-ET affects apoptosis of human granulosa-luteal cells and expression of peripheral benzodiazepine receptor (PBR) protein involved in the apoptosis of the cells. METHODS:...
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Characterization of Nitric Oxide (NO)-Induced Cell Death in Lung Epithelial Cells

Yong WS, Kim YS, Park JS, Jee YK, Lee KY

BACKGROUND: Nitric Oxide (NO) is a multi-faceted molecule with dichotomous regulatory roles in many areas of biology. NO can promote apoptosis in some cells, whereas it inhibits apoptosis in other...
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The Effect of Rutin on the Melanogenesis and Nitric Oxide in UVB-irradiated HM3KO Human Melanoma

Lee SY, Kim YM, Lee JK, Yoo SJ, Mun YJ, Woo WH

  • KMID: 1894517
  • Korean J Anat.
  • 2003 Feb;36(1):49-56.
Ultraviolet (UV) radiation is the main physiological stimulus for human skin pigmentation. Recently, nitric oxide (NO) have been involved in mediation of skin pigmentation induced by UVB. Rutin, a flavonoid...
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Neuroprotective Effect of Estrogen on Motor Neuron Cells Expressing Wild Type or Mutant Cu/Zn Superoxide Dismutase

Kim HJ, Park SH, Kim MH, Kim HJ, Lee KW

  • KMID: 2343020
  • J Korean Neurol Assoc.
  • 2002 Sep;20(5):525-529.
BACKGROUND: Recently, the mechanism involved in nitric oxide (NO)-mediated motor neuron death is under extensive investigation. The role of Cu/Zn superoxide dismutase (SOD) mutation, which is found in about 2%...
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The role of nitric oxide in ocular surface diseases

Park GS, Kwon NS, Kim YM, Kim JC

The role of nitric oxide (NO) in ocular surface diseases remains unknown. We investigated the conditions leading to increase NO generation in tears and the main sources of ocular surface...
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The Role of Calcium Affecting Signal Pathway Related to Nitric Oxide-induced Cytotoxicity in H9c2 Cardiac Myoblast

Lee BH, Jung KM, Ahn BK, Mun YJ, Oh JM, Kim JJ, Choi MK, Park ST, Chung YT

  • KMID: 2224547
  • Korean J Anat.
  • 2000 Oct;33(5):587-594.
Nitric oxide (NO) elevates intracellular calcium. But the actions of calcium in NO-induced cell death are not well understood. This study was carried out to investigate the signal transduction pathways...
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Protective Effect of Nitric Oxide Against Lipopolysaccharide-induced Cytotoxicity in C6-glial Cell

Hwang HG, Her JM, Bang HJ, Kim BY, Sohn HM, Mun YJ, Oh JM, Chung YT, Choi MK

  • KMID: 2224546
  • Korean J Anat.
  • 2000 Oct;33(5):579-586.
Nitric oxide (NO) is mainly involved in brain ischemic damage to elucidate the protective mechanism of NO pretreatment on ischemic-induced cytotoxicity. This study was investigated whether NO pretreatment inhibits the...
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Effects of Nitric Oxide on the Maturation of Mouse Oocyte in vitro

Kim JL, Lee KY, Park HJ, Kwon YS, Lee YI

  • KMID: 2075948
  • Korean J Obstet Gynecol.
  • 1999 Nov;42(11):2542-2548.
OBJECTIVE: Nitric oxide (NO) produced in ovary may contribute to follicle maturation, ovulation, oocyte maturation and luteinization. In this study, the effect of nitric oxide on the spontaneous maturation of...
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Expression of Vascular Endothelial Growth Factor and iNOS in Pterygia

Lee KJ, Joo MJ, Lee DH

  • KMID: 2108776
  • J Korean Ophthalmol Soc.
  • 1999 Aug;40(8):2087-2093.
To evaluate the expression of vascular endothelial growth factor (VEGF) in pterygia and seek the reciprocal relationships between VEGF and nitric oxide (NO) in development of pterygia. Conjunctiva sampled during...
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