Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

57 results
Display

Clinical Genetic Testing in Children with Kidney Disease

Kang E, Lee BH

Chronic kidney disease, the presence of structural and functional abnormalities in the kidneys, is associated with a lower quality of life and increased morbidity and mortality in children. Genetic etiologies...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Utility of Next-Generation Sequencing for Deciphering Intratumor Heterogeneity in Prostate Cancer

Joung JG, Park JY, Yang SY, Jeong J

Prostate cancer has long been considered a disease with a heterogeneous phenotype. The intratumor heterogeneity (ITH) may affect diverse phenotypes such as treatment response, drug resistance, and overall clinical outcomes....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Identification of 8-Digit HLA-A, -B, -C, and -DRB1 Allele and Haplotype Frequencies in Koreans Using the One Lambda AllType Next-Generation Sequencing Kit

Choe W, Chae JD, Yang JJ, Hwang SH, Choi SE, Oh HB

Background: Recent studies have successfully implemented next-generation sequencing (NGS) in HLA typing. We performed HLA NGS in a Korean population to estimate HLA-A, -B, -C, and -DRB1 allele and haplotype...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Targeted Next-Generation Sequencing of Plasma CellFree DNA in Korean Patients with Hepatocellular Carcinoma

Chae H, Sung PS, Choi H, Kwon A, Kang D, Kim Y, Kim M, Yoon SK

Background: Hepatocellular carcinoma (HCC) is the second-most-common cause of cancer-related deaths worldwide, and an accurate and non-invasive biomarker for the early detection and monitoring of HCC is required. We assessed...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Recent Advances in the Clinical Application of Next-Generation Sequencing

Ki CS

Next-generation sequencing (NGS) technologies have changed the process of genetic diagnosis from a gene-by-gene approach to syndrome-based diagnostic gene panel sequencing (DPS), diagnostic exome sequencing (DES), and diagnostic genome sequencing...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Application of Next Generation Sequencing in Laboratory Medicine

Zhong Y, Xu F, Wu J, Schubert J, Li MM

The rapid development of next-generation sequencing (NGS) technology, including advances in sequencing chemistry, sequencing technologies, bioinformatics, and data interpretation, has facilitated its wide clinical application in precision medicine. This review...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
DNA-protein biomarkers for immunotherapy in the era of precision oncology

Kim B, Kang SY, Kim KM

The use of biomarkers to guide patient and therapy selection has gained much attention to increase the scope and complexity of targeted therapy options and immunotherapy. Clinical trials provide a...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Prediction of TP53 mutations by p53 immunohistochemistry and their prognostic significance in gastric cancer

Hwang HJ, Nam SK, Park H, Park Y, Koh J, Na HY, Kwak Y, Kim WH, Lee HS

Background: Recently, molecular classifications of gastric cancer (GC) have been proposed that include TP53 mutations and their functional activity. We aimed to demonstrate the correlation between p53 immunohistochemistry (IHC) and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Clinical Implications of Circulating Tumor DNA from Ascites and Serial Plasma in Ovarian Cancer

Han MR, Lee SH, Park JY, Hong H, Ho JY, Hur SY, Choi YJ

Purpose The purpose of this study was to identify the clinical utility of circulating tumor DNA (ctDNA) from ascites and serial plasma samples from epithelial ovarian cancer (EOC) patients. Materials and Methods Using...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Detection of Germline Mutations in Breast Cancer Patients with Clinical Features of Hereditary Cancer Syndrome Using a Multi-Gene Panel Test

Shin HC, Lee HB, Yoo TK, Lee ES, Kim RN, Park B, Yoon KA, Park C, Lee ES, Moon HG, Noh DY, Kong SY, Han W

Purpose Hereditary cancer syndrome means that inherited genetic mutations can increase a person's risk of developing cancer. We assessed the frequency of germline mutations using an nextgeneration sequencing (NGS)–based multiple-gene panel...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Assessment of Bacterial and Fungal Biodiversity in Korean Dermatomycoses Patients: A Pilot Study

Chung BY, Seo JM, Kang MJ, Lee M, Shin J, Chung YJ, Yu DS, Lee YB

Background: Dermatophytes are the most common cause of fungal infections worldwide, having an estimated prevalence of 20% by the World Health Organization. Recent advances of sequencing and annotation of fungi...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Genetic tests by next-generation sequencing in children with developmental delay and/or intellectual disability

Han JY, Lee IG

Developments in next-generation sequencing (NGS) techogies have assisted in clarifying the diagnosis and treatment of developmental delay/intellectual disability (DD/ID) via molecular genetic testing. Advances in DNA sequencing technology have not...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Factors of Endoscopic Ultrasound-Guided Tissue Acquisition for Successful Next-Generation Sequencing in Pancreatic Ductal Adenocarcinoma

Park JK, Lee JH, Noh DH, Park JK, Lee KT, Lee JK, Lee KH, Jang KT, Cho J

Background/Aims: Recent advances in understanding the genetics of pancreatic ductal adenocarcinoma (PDAC) have led to the potential for a personalized approach. Several studies have described the feasibility of generating genetic...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Detection of Targetable Genetic Alterations in Korean Lung CancerPatients: A Comparison Study of Single-Gene Assays andTargeted Next-Generation Sequencing

Park E, Shim HS

Purpose Epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), and ROS proto-oncogene 1 (ROS1) are ‘must-test’ biomarkers in the molecular diagnostics of advanced- stage lung cancer patients. Although single-gene assays are currently...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Next-Generation Sequencing in Prostate Cancer

Yu SH, Kang TW

Prostate cancer is one of the most common cancer worldwide, androgen-deprivation therapy (ADT) has been the mainstream of treatment after treatment failure of localized cancer. However, despite the rapid initial...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
PAIVS: prediction of avian influenza virus subtype

Park HC, Shin J, Cho SM, Kang S, Chung YJ, Jung SH

Highly pathogenic avian influenza (HPAI) viruses have caused severe respiratory disease and death in poultry and human beings. Although most of the avian influenza viruses (AIVs) are of low pathogenicity...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Three-Year Experience of an External ProficiencyTesting Survey for Next-Generation Sequencing-Based Testing for Germline Mutation

Seong MW, Kim M, Shin HS, Cho SI, Park SS

Background: Next-generation sequencing is a powerful technology thatallows simultaneous analysis of several genes but also demands a welldesignedquality management system owing to its complexity. We aimed toanalyze the results of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Genetic Characterization of Molecular Targets in Korean Patients with Gastrointestinal Stromal Tumors

Park J, Yoo HM, Sul HJ, Shin S, Lee SW, Kim JG

PURPOSE: Gastrointestinal stromal tumors (GISTs) frequently harbor activating gene mutations in either KIT or platelet-derived growth factor receptor A (PDGFRA) and are highly responsive to several selective tyrosine kinase inhibitors....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Application of 16S rRNA Gene-Targeted Next-Generation Sequencing for Bacterial Pathogen Detection in Continuous Ambulatory Peritoneal Dialysis Peritonitis

Kim YA, Kang EW, Moon HS, Kim D, Yong D

BACKGROUND: 16S rRNA gene-targeted next-generation sequencing (NGS) can detect microorganisms in a comprehensive reference database. To date, NGS has been successfully applied to samples such as urine, blood, and synovial...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Clinical Validity of Next-Generation Sequencing Multi-Gene Panel Testing for Detecting Pathogenic Variants in Patients With Hereditary Breast-Ovarian Cancer Syndrome

Yoo J, Lee GD, Kim JH, Lee SN, Chae H, Han E, Kim Y, Kim M

BACKGROUND: Hereditary breast and ovarian cancer syndrome (HBOC) is caused by pathogenic variants in BRCA and other cancer-related genes. We analyzed variants in BRCA gene and other cancer-related genes in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr