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Neuroleptic malignant syndrome cases in a Moroccan intensive care unit: a retrospective analysis and literature review

Touzani S, Hamdouni M, Houari N, Khbiza YY, Elbouazzaoui A, Boukatta B, Kanjaa N

Background: Neuroleptic malignant syndrome (NMS) is a rare but potentially life-threatening neuropsychiatric emergency. The aim of our study was to update our bedside procedures by investigating NMS cases managed in...
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Electroconvulsive Therapy for Parkinson’s Disease with Depression and Neuroleptic Malignant Syndrome: A Case Report

Mori Y, Miura I, Nozaki M, Osakabe Y, Izumi R, Akama T, Kimura S, Yabe H

Parkinson’s disease is often complicated by psychiatric symptoms. Psychiatrists are caught in a dilemma between such symptoms and physical treatment since Parkinson’s disease sometimes shows treatment resistance based on pharmacological...
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Neuroleptic Malignant Syndrome Applied with Targeted Temperature Management

Yun SY, Kim HJ, Park HJ, Yang SK, Lee B, Han MK, Jeong HG

Neuroleptic malignant syndrome (NMS) is a life-threatening neurologic emergency associated with the use of dopamine receptor-antagonist properties or the rapid withdrawal of dopaminergic medications. NMS is characterized by refractory hyperpyrexia,...
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Acute Colonic Pseudo-obstruction Induced by Neuroleptic Malignant Syndrome

Ryu SJ, Lee JY, Lee JH

A colonic pseudo-obstruction is a disorder that causes abdominal distension and abdominal pain similar to a mechanical obstruction, but there are no structural lesions that can obstruct the gastrointestinal tract....
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Drug-induced Hyperthermic Syndromes in Psychiatry

Caroff SN, Watson CB, Rosenberg H

Hyperthermia, or extreme elevations in body temperature, can be life-threatening and may be caused by prescription drugs or illegal substances acting at a number of different levels of the neuraxis....
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Risk of Neuroleptic Malignant Syndrome with Vesicular Monoamine Transporter Inhibitors

Caroff SN

Objective: Vesicular monoamine transporter-2 (VMAT2) inhibitors have been proven to be effective for the treatment of tardive dyskinesia and their use is likely to increase. The evidence base of published...
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Rhabdomyolysis and Neuroleptic Malignant Syndrome Associated with Very Low-dose Antipsychotics in Children and Adolescent

Park JI, Park TW

Along with the field of adult psychiatry, antipsychotic agents are increasingly used in the field of child and adolescent psychiatry. Although neuroleptic malignant syndrome (NMS) and rhabdomyolysis are rare complication...
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A Neuroleptic Malignant Syndrome Without Rigidity

Özdemir I, Kuru E, Safak Y, Tulacı RG

Neuroleptic malignant syndrome (NMS) is an uncommon but potentially lethal idiosyncratic reaction which may emerge in the aftermath of the treatments with neuroleptics demonstrating itself with the symptoms of altered...
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Clozapine Induced Neuroleptic Malignant Syndrome

Jo YS, Jo HA, Yu BC, Shin JH, Oh KH

Neuroleptic malignant syndrome is a rare, but potentially life-threatening adverse event associated with the use of neuroleptic agents. We describe the case of a 47-year-old schizophrenic woman who was treated...
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Progressive Encephalomyelitis with Rigidity and Myoclonus in an Intellectually Disabled Patient Mimicking Neuroleptic Malignant Syndrome

Xu Z, Prasad K, Yeo T

We present a case of 32-year-old male with profound mental retardation and autism spectrum disorder who had presented with seizures, rigidity and elevated creatine kinase and was initially diagnosed as...
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Neuroleptic Malignant Syndrome Associated with Valproate in an Adolescent

Yıldırım V, Direk MC, Güneş S, Okuyaz C, Toros F

Neuroleptic malignant syndrome (NMS) is a life-threatening idiosyncratic reaction that usually occurs after the administration of antipsychotic drugs. Antidepressants, benzodiazepines, and antiepileptic drugs are also suggested to be associated with...
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Venous Thromboembolism Following Dantrolene Treatment for Neuroleptic Malignant Syndrome

Chen PH, Lane HY, Lin CH

Neuroleptic malignant syndrome (NMS) is one of the most severe iatrogenic emergencies in clinical service. The symptoms including sudden consciousness change, critical temperature elevation and electrolytes imbalance followed by mutli-organ...
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Malignant Neuroleptic Syndrome following Deep Brain Stimulation Surgery of Globus Pallidus Pars Internus in Cerebral Palsy

Lee JM, Paek SH, Park HR, Lee KH, Shin CW, Park HY, Park HP, Kim DG, Jeon BS

Neuroleptic malignant syndrome (NMS) is a rare but potentially lethal outcome caused by sudden discontinuation or dose reduction of dopaminergic agents. We report an extremely rare case of NMS after...
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Recurrent Idiopathic Catatonia: Implications beyond the Diagnostic and Statistical Manual of Mental Disorders 5th Edition

Caroff SN, Hurford I, Bleier HR, Gorton GE, Campbell E

We describe a case of recurrent, life-threatening, catatonic stupor, without evidence of any associated medical, toxic or mental disorder. This case provides support for the inclusion of a separate category...
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Neuroleptic Malignant Syndrome in Children and Adolescents : A Review

Kwack YS, Ryu JS

  • KMID: 2291634
  • J Korean Acad Child Adolesc Psychiatry.
  • 2013 Mar;24(1):13-20.
Neuroleptic malignant syndrome (NMS) is a severe iatrogenic complication of treatment with antipsychotic medication. The aim of this review is to provide the clinical characteristics and treatments of children and...
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Olanzapine-Induced Diabetic Ketoacidosis and Neuroleptic Malignant Syndrome with Rhabdomyolysis: A Case Report

Sa YK, Yang H, Jung HK, Son JW, Lee SS, Kim SR, Cha BY, Son HY, Pae CU, Yoo SJ

Atypical antipsychotics have replaced conventional antipsychotics in the treatment of schizophrenia because they have less of a propensity to cause undesirable neurologic adverse events including extrapyramidal symptoms, tardive dyskinesia, and...
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Neuroleptic Malignant Syndrome Caused by Long Term Intake of Haloperidol

Jo JH, Park HJ, Park SS, Ha YS, Lee HS, Park HY, Chang H, Kim YS, Cho KH

  • KMID: 2343406
  • J Korean Neurol Assoc.
  • 2011 Aug;29(3):214-215.
Neuroleptic malignant syndrome (NMS) is a fatal complication most often caused by an adverse reaction to neuroleptic or antipsychotic drugs, and is mostly brought out in the initial stage of...
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A Case of Catatonia and Neuroleptic Malignant Syndrome Probably Associated with Antipsychotic in Korea

Choi HD, Kim KK, Koo BH

  • KMID: 2316052
  • Psychiatry Investig.
  • 2011 Jun;8(2):174-177.
Several studies have reported on catatonia caused by the use of antipsychotic drugs and on the association between catatonia and neuroleptic malignant syndrome (NMS), but none has reported such a...
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A Case of Myoglobinuric Acute Kidney Injury due to Rhabdomyolysis Associated with Neuroleptic Malignant Syndrome

Cho JN, Lee IH

  • KMID: 2307139
  • Korean J Nephrol.
  • 2011 Jan;30(1):87-93.
Neuroleptic malignant syndrome (NMS) is a rare, adverse reaction associated with the use of neuroleptic medication, which is characterized by altered consciousness, muscle rigidity, autonomic instability, hyperthermia, and elevated serum...
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Neuroleptic Malignant Syndrome Complicated with Acute Renal Failure Secondary to Quetiapine: A Case Report

Choi HJ, Oh SB

  • KMID: 2332723
  • J Korean Soc Emerg Med.
  • 2010 Apr;21(2):278-281.
Neuroleptic malignant syndrome (NMS) is an idiosyncratic, life-threatening complication of treatment with antipsychotic drugs, and this is characterized by fever, severe muscle rigidity and changes of the autonomic nervous system...
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