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Sensory assessment of meshed skin grafts over free gracilis muscle flaps without nerve coaptation for lower extremity reconstruction

Tremp M, Waldkircher NJ, Wang W, Oranges CM, di Summa PG, Zhang Y, Wang W, Schaefer DJ, Kalbermatten DF

Background Little is known about the sensate recovery of skin grafts over free non-neurotized muscle flaps. The aim of this study was to evaluate the sensitivity of free gracilis muscle...
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Sensory recovery after infraorbital nerve avulsion injury

Lee SY, Kim SH, Hwang JH, Kim KS

The infraorbital nerve is a branch of the trigeminal nerve. Injury to the infraorbital nerve can be caused by trauma, including various facial fractures. Due to this nerve injury, patients...
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Pim-1 Protects Retinal Ganglion Cells by Enhancing Their Regenerative Ability Following Optic Nerve Crush

Zhang S, Shuai L, Wang D, Huang T, Yang S, Miao M, Liu F, Xu J

  • KMID: 2503984
  • Exp Neurobiol.
  • 2020 Jun;29(3):249-272.
  • doi: 10.5607/en20019
Provirus integration site Moloney murine leukemia virus (Pim-1) is a proto-oncogene reported to be associated with cell proliferation, differentiation and survival. This study was to explore the neuroprotective role of...
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Centella asiatica (L.)-Neurodifferentiated Mesenchymal Stem Cells Promote the Regeneration of Peripheral Nerve

Hussin HM, Lawi MM, Haflah NHM, Kassim AYM, Idrus RBH, Lokanathan Y

BACKGROUND: Centella asiatica (L.) is a plant with neuroprotective and neuroregenerative properties; however, its effects on the neurodifferentiation of mesenchymal stem cells (MSCs) and on peripheral nerve injury are poorly...
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Schwann Cells Enhance Penetration of Regenerated Axons into Three-Dimensional Microchannels

Liu C, Kray J, Chan C

Nerve regeneration after injury requires proper axon alignment to bridge the lesion site and myelination to achieve functional recovery. Transplanted scaffolds with aligned channels, have been shown to induce axon...
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Effects of Canine and Murine Mesenchymal Stromal Cell Transplantation on Peripheral Nerve Regeneration

Sanchez DN, Bertanha M, Fernandes , de Lima Resende LA, Deffune E, Amorim RM

BACKGROUND AND OBJECTIVES: Maintaining a permissive microenvironment is essential for adequate nerve regeneration. Cell-based therapy has the potential based cell replacement and promotion of axonal growth. The adipose tissue derived...
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Neural Ablation and Regeneration in Pain Practice

Choi EJ, Choi YM, Jang EJ, Kim JY, Kim TK, Kim KH

A nerve block is an effective tool for diagnostic and therapeutic methods. If a diagnostic nerve block is successful for pain relief and the subsequent therapeutic nerve block is effective...
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Anatomical study of the nerve regeneration after selective neurectomy in the rabbit: clinical application for esthetic calf reduction

Shin KJ, Yoo JY, Lee JY, Gil YC, Kim JN, Koh KS, Song WC

The purposes of this study were therefore to characterize the degeneration and regeneration of nerves to the calf muscles after selective neurectomy, both macroscopically and microscopically, and to determine the...
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Etifoxine for Pain Patients with Anxiety

Choi YM, Kim KH

Etifoxine (etafenoxine, Stresam(R)) is a non-benzodiazepine anxiolytic with an anticonvulsant effect. It was developed in the 1960s for anxiety disorders and is currently being studied for its ability to promote...
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Application of Mesenchymal Stem Cells in Rhinologic Fields

Cho KS

Mesenchymal stem cells (MSCs) are adult stem cells which are present in a variety of adult tissues and reside in essentially all post-natal organs and tissues. MSCs represent an important...
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Effect of Macrophage Migration Inhibitory Factor on Corneal Sensitivity after Laser In Situ Keratomileusis in Rabbit

Hyon JY, Hose S, Gongora C, Sinha D, O'Brien T

PURPOSE: To investigate the effect of macrophage migration inhibitory factor (MIF) on corneal sensitivity after laser in situ keratomileusis (LASIK) surgery. METHODS: New Zealand white rabbits were used in this study....
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Controlled release of nerve growth factor from heparin-conjugated fibrin gel within the nerve growth factor-delivering implant

Lee JY, Kim SM, Kim MJ, Lee JH

OBJECTIVES: Although nerve growth factor (NGF) could promote the functional regeneration of an injured peripheral nerve, it is very difficult for NGF to sustain the therapeutic dose in the defect...
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Rat Peripheral Nerve Regeneration Using Nerve Guidance Channel by Porcine Small Intestinal Submucosa

Yi JS, Lee HJ, Lee HJ, Lee IW, Yang JH

OBJECTIVE: In order to develop a novel nerve guidance channel using porcine small intestinal submucosa (SIS) for nerve regeneration, we investigated the possibility of SIS, a tissue consisting of acellular...
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Sensory Axon Regeneration: A Review from an in vivo Imaging Perspective

Han SB, Kim H, Skuba A, Tessler A, Ferguson T, Son YJ

Injured primary sensory axons fail to regenerate into the spinal cord, leading to chronic pain and permanent sensory loss. Re-entry is prevented at the dorsal root entry zone (DREZ), the...
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Vein Wrapping Technique for Nerve Reconstruction in Patients with Thyroid Cancer Invading the Recurrent Laryngeal Nerve

Yoo YM, Lee IJ, Lim H, Kim JH, Park MC

Recurrent laryngeal nerve paralysis is the most common and serious complication after thyroid cancer surgery. The objective of this study was to report the advantages of the vein wrapping technique...
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Botulinum Toxin A Treatment for Patients with Periorbital Spasm after Facial Nerve Paresis

Lee JY, Park JS, Lew H

PURPOSE: To evaluate clinical features of periorbital spasm and facial asymmetry in the patients who recovered poorly from Bell's palsy and facial trauma and to investigate the effect of Botulinum...
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Effect of Platelet-rich Plasma(PRP) on Regeneration of Rat Sciatic Nerve in a Silicone Chamber

Minn KW, Jeong EC, Chang H, Kwon ST, Kim SW, Baek RM

  • KMID: 2322224
  • J Korean Soc Plast Reconstr Surg.
  • 2010 Mar;37(2):105-109.
PURPOSE: The purpose of this study is to determine the effect of platelet-rich plasma(PRP) on rat sciatic nerve regeneration in a 10mm silicone chamber. METHODS: A total of 6 inbred Lewis...
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Comparison of Processed Nerve Allograft and Laminin Derived Peptide Incorporated Nerve Conduit for Peripheral Nerve Regeneration

Lee JY, Choi MH, Shin EY, Min BM, Roh D, Chung DJ

PURPOSE: To compare a processed nerve allograft, laminin derived peptide incorporated nerve conduit, and autograft in terms of electrodiagnostic testing and nerve histomorphometry for peripheral nerve regeneration in a rabbit...
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Comparison of the Nerve Regenerating Effect of Inside-out Vein Grafts, Muscle-filled Inside-out Vein Grafts, and Fat-interposed Inside-out Vein Grafts in Rats

Lee JH, Chung DW

PURPOSE: We wanted to compare the nerve regeneration of inside-out vein grafts, muscle-filled inside-out vein grafts and fat-interposed inside-out vein grafts to repair the 10 mm sciatic nerve defects in...
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The Effect of Human Muscle-Derived Stem Cells (MDSC) and Glycine-Isoleucine-Lysine-Valine-Alanine-Valine (GIKVAV) on the Cryo-Injured Bladder of Nude Mouse

Lee YS, Lee JY, Kwon EB, Kim HY, Cho HJ, Kim SW, Hwang TK, Byun SS, Han DK, Lee JY

  • KMID: 2311847
  • Korean J Urol.
  • 2009 May;50(5):480-485.
PURPOSE: In neurogenic bladder, both smooth muscle contraction and nerve regeneration are very important for functional improvement. Glycine-isoleucine-lysine-valine-alanine-valine (GIKVAV) is a peptide that can induce nerve regeneration in vivo. In...
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