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Statin-Induced Immune-Mediated Necrotizing Myopathy with Anti-HMGCR Antibody

Lee J, Kim E, Kim N, Park HJ, Kim YH

Anti-3-hydroxy-3-methylglutaryl coenzyme A reductase (anti-HMGCR) antibody related immune-mediated necrotizing myopathy (IMNM) are usually associated with statin use. The disease has features of persistent muscle weakness and creatine kinase (CK) elevation...
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Statin-Naïve Paraneoplastic Anti-HMGCR Myopathy

Yung Y, Kim BY, Oh K, Cho JY

Anti-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (anti-HMGCR) myopathy is a subtype of immune-mediated necrotizing myopathy regardless of exposure to statins. Necrotizing myopathy is distinguished by necrotic muscle fibers with a relative...
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Paraneoplastic Necrotizing Myopathy Associated With Ovarian Adenocarcinoma

Lee HM, Kim JS, Kim M, Kang SH, Hong JH, Park SH, Kim JH

  • KMID: 1708062
  • J Korean Neurol Assoc.
  • 2014 Feb;32(1):34-37.
We describe here a case of female patient who presented with mild proximal weakness, myalgia, and markedly elevated CPK, which could be ascribed to paraneoplastic necrotizing myopathy in association with...
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Statin-Induced Autoimmune Necrotizing Myopathy Responsive to Immunosuppressive Therapy

Park YE, Seo JD, Kim DS

  • KMID: 1492126
  • J Korean Soc Clin Neurophysiol.
  • 2012 Dec;14(2):76-79.
Statin is commonly used for lowering cholesterols and can be myotoxic to cause drug-induced necrotizing myopathy. Statin-induced myopathy ranges from asymptomatic hyperCKemia to lethal rhabdomyolysis but is usually reversed by...
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Esophageal Cancer-Associated Paraneoplastic Necrotizing Myopathy

Kim DH, Sohn SY, Choi YC, Joo IS

  • KMID: 2343391
  • J Korean Neurol Assoc.
  • 2010 Nov;28(4):337-338.
No abstract available.
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