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Development of Analytical Method and Validation using HPLC/PDA for Discrimination between Artemisiae Argyi Folium and Artemisiae Iwayomogii Herba

Le DD, Nguyen DH, Zhao BT, Min BS, Woo MH

  • Nat Prod Sci.
  • 2019 Sep;25(3):275-283.
  • doi: 10.20307/nps.2019.25.3.275
In this study, we described the new developed method to simultaneously discriminate two herbal drugs of Artemisiae Argyi Folium and Artemisiae Iwayomogii Herba using eight marker compounds (1 – 8)...
Phytochemical Constituents of the Root Bark from Morus alba and Their Il-6 Inhibitory Activity

Chang YS, Jin HG, Lee H, Lee DS, Woo ER

  • Nat Prod Sci.
  • 2019 Sep;25(3):268-274.
  • doi: 10.20307/nps.2019.25.3.268
Morus alba L., known as white mulberry, is a medicinal plant belongs to family Moraceae. It has long been used commonly in Ayurvedic for the treatment of lung-heat, cough, asthma,...
Dioscorea japonica Thunb. Ethanolic Extract Attenuated Oxazolone-Induced Atopic Dermatitis-like Skin Lesions in BALB/c Mice

Jegal J, Park NJ, Jo BG, Kim SN, Yang MH

  • Nat Prod Sci.
  • 2019 Sep;25(3):261-267.
  • doi: 10.20307/nps.2019.25.3.261
The rhizomes of Dioscorea japonica Thunb. are widely consumed as food and also used to treat diabetes and polyuria in Korea. This study was undertaken to study the anti-atopic dermatitis...
Anti-oxidative Effect of Piperine from Piper nigrum L. in Caenorhabditis elegans

Park HM, Kim JH, Kim DK

  • Nat Prod Sci.
  • 2019 Sep;25(3):255-260.
  • doi: 10.20307/nps.2019.25.3.255
Piper nigrum L. (Piperaceae), which is a well-known food seasoning, has been used as a traditional medicine for the treatment of vomiting, abdominal pain, diarrhea and anorexia in Korea, China...
Growth Factor- and Phorbol Ester-induced Production and Gene Expression of MUC5AC Mucin in Human Airway Epithelial NCI-H292 Cells Were Inhibited by Afzelin and Natural Products Derived from Houttuynia Cordata

Kim YJ, Lee HJ, Lee CJ

  • Nat Prod Sci.
  • 2019 Sep;25(3):248-254.
  • doi: 10.20307/nps.2019.25.3.248
In the present study, we investigated whether quercitrin, quercetin and afzelin derived from Houttuynia cordata affect the production and gene expression of MUC5AC mucin from airway epithelial cells. Confluent NCI-H292...
Flavestin K, An Isoprenylated Stilbene from the Leaves of Macaranga recurvata Gage

Tjahjandarie TS, Tanjung M, Saputri RD, Nadar PB, Aldin MF, EvaMarliana , Permadi A

  • Nat Prod Sci.
  • 2019 Sep;25(3):244-247.
  • doi: 10.20307/nps.2019.25.3.244
A new isoprenylated stilbene, flavestinK (1) together with two known isoprenylated stilbenes, flavestin B (2), flavestin G (3), and two isoprenilated flavanones, 4-O-methyl-8-isoprenylnaringenin (4) and 8-isoprenyl-5,7-dihydroxyflavanone (5) were isolated from...
Quantification of the Bioactive Components of the Rhizomes of Curcuma wenyujin and Assessment of Its Anti-inflammatory Effect in Benign Prostatic Hyperplasia-1 Cells

Seo CS, Park E, Lee MY, Shin HK

  • Nat Prod Sci.
  • 2019 Sep;25(3):238-243.
  • doi: 10.20307/nps.2019.25.3.238
In this study, the marker compounds of Curcumae Rhizoma (CR) were simultaneously quantified by high-performance liquid chromatography equipped with a photodiode array detector and the anti-inflammatory effects of CR extract...
Diels-Alder Type Adducts from Hairy Root Cultures of Morus macroura

Happyana N, Hakim EH, Syah YM, Kayser O, Juliawaty , Mujahidin , Ermayanti , Achmad SA

  • Nat Prod Sci.
  • 2019 Sep;25(3):233-237.
  • doi: 10.20307/nps.2019.25.3.233
Three Diels-Alder type adducts, guangsangon E (1), chalcomoracin (2) and sorocein I (3) were isolated from hairy root cultures of Morus macroura. The structures of the isolated compounds (1 –...
Xylaroisopimaranin A, a New Isopimarane Derivative from an Endophytic Fungus Xylaralyce sp.

Bao SS, Liu HH, Zhang XQ, Liu CX, Li XC, Guo ZY

  • Nat Prod Sci.
  • 2019 Sep;25(3):228-232.
  • doi: 10.20307/nps.2019.25.3.228
Five secondary metabolites, including a new isopimarane derivative xylaroisopimaranin A (1), were isolated from the endophytic fungus Xylaralyce sp. (HM-1), and their structures were elucidated by 1D, 2D NMR, MS...
Assessment of the Purity of Emodin by Quantitative Nuclear Magnetic Resonance Spectroscopy and Mass Balance

Park S, Choi YJ, Do GH, Seo EK, Hyun S, Lee D

  • Nat Prod Sci.
  • 2019 Sep;25(3):222-227.
  • doi: 10.20307/nps.2019.25.3.222
Quantitative nuclear magnetic resonance (qNMR) is a well-established method adopted by international pharmacopoeia for quantitative and purity analyses. Emodin is a type of anthraquinone, well known as the main active...
Anti-inflammatory Activity of Sambucus Plant Bioactive Compounds against TNF-α and TRAIL as Solution to Overcome Inflammation Associated Diseases: The Insight from Bioinformatics Study

Putra WE, Ode Salma , Rifa'i M

  • Nat Prod Sci.
  • 2019 Sep;25(3):215-221.
  • doi: 10.20307/nps.2019.25.3.215
Inflammation is the crucial biological process of immune system which acts as body's defense and protective response against the injuries or infection. However, the systemic inflammation devotes the adverse effects...
The Effect of Trigonella foenum-graceum L. (Fenugreek) Towards Collagen Type I Alpha 1 (COL1A1) and Collagen Type III Alpha 1 (COL3A1) on Postmenopausal Woman's Fibroblast

Yusharyahya SN, Bramono K, Sutanto NR, Kusuma I

  • Nat Prod Sci.
  • 2019 Sep;25(3):208-214.
  • doi: 10.20307/nps.2019.25.3.208
Trigonella foenum-graceum L. (fenugreek) is a phytoestrogen, a nonsteroidal organic chemical compound from plants which has similar mechanism of action to sex hormone estradiol-17β. This study aims to assess the...
Albizzia julibrissin Suppresses Testosterone-induced Benign Prostatic Hyperplasia by Regulating 5α-Reductase Type 2 – Androgen Receptor Pathway

Hong GL, Kim HT, Park SR, Lee NH, Ryu KA, Kim TW, Song GY, Jung JY

  • Nat Prod Sci.
  • 2019 Sep;25(3):200-207.
  • doi: 10.20307/nps.2019.25.3.200
Albizzia julibrissin (AJ) is an herbal medicine that shows low toxicity, promotes promoting blood circulation and mitigates the inflammation and has mild side effects. Benign prostate hyperplasia (BPH) is one...
Ethnobotany, Phytochemistry, and Pharmacology of Angelica decursiva Fr. et Sav.

Ali MY, Seong SH, Jannat S, Jung HA, Choi JS

  • Nat Prod Sci.
  • 2019 Sep;25(3):181-199.
  • doi: 10.20307/nps.2019.25.3.181
Angelica decursiva Fr. et Sav. (Umbelliferae) has traditionally been used to treat different diseases due to its antitussive, analgesic, and antipyretic activities. It is also a remedy for thick phlegm,...

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