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Nitric Oxide Inhibitory Constituents from the Fruits of Amomum tsao-ko

Kim JG, Le TP, Hong HR, Han JS, Ko JH, Lee SH, Lee MK, Hwang BY

  • Nat Prod Sci.
  • 2019 Mar;25(1):76-80.
  • doi: 10.20307/nps.2019.25.1.76
Bioactivity-guided fractionation of MeOH extract of the dried fruits of Amomum tsao-ko led to isolation of nine compounds (1 – 9). Their structures were elucidated by spectroscopic methods including extensive...
Cytotoxic Constituents from the Roots of Asarum sieboldii in Human Breast Cancer Cells

Kim E, Kim HJ, Oh HN, Kwak AW, Kim SN, Kang BY, Cho SS, Shim JH, Yoon G

  • Nat Prod Sci.
  • 2019 Mar;25(1):72-75.
  • doi: 10.20307/nps.2019.25.1.72
Bioassay-guided fractionation of the roots of Asarum sieboldii led to the isolation of the six compounds methylkakuol (1), sesamin (2), asarinin (3), xanthoxylol (4), and (2E,4E,8Z,10E/Z)-N-(2-methylpropyl) dodeca-2,4,8,10-tetraenamide (5/6). Among the...
Anti-nociceptive and Anti-inflammatory Properties of Ilex latifolia and its Active Component, 3,5-Di-caffeoyl Quinic Acid Methyl Ester

Kim JY, Lee HK, Seong YH

  • Nat Prod Sci.
  • 2019 Mar;25(1):64-71.
  • doi: 10.20307/nps.2019.25.1.64
The present study was conducted to investigate anti-nociceptive and anti-inflammatory effects of the leaves of Ilex latifolia Thunb (I. latifolia) in in vivo and in vitro. Writhing responses induced by...
Hematopoiesis Activity of Sambucus javanica on Chloramphenicol-induced Aplastic Anemia Mouse Model

Putra WE, Rifa'i M

  • Nat Prod Sci.
  • 2019 Mar;25(1):59-63.
  • doi: 10.20307/nps.2019.25.1.59
Hematopoiesis has a pivotal role in the maintenance of body homeostasis. Ironically, several hematological disorder caused by chemicals, drugs, and other environmental factors lead to severe bone marrow failure. Current...
Study on the Marker Steroids of New Zealand Deer (Cervus elaphus var. scoticus) Velvet Antler by UPLC-MS/MS and HPLC-PDA Methods - (II)

Lee NK, Jang KH, Lee JT, Park HW, Han ST, In G

  • Nat Prod Sci.
  • 2019 Mar;25(1):49-58.
  • doi: 10.20307/nps.2019.25.1.49
Eleven steroid hormones (SHs: androstene-3,17-dione, estrone, β-estradiol, α-estradiol, testosterone, dehydroepiandrosterone, 17á-hydroxyprogesterone, medroxyprogesterone, megestrol acetate, progesterone, and androsterone) were detected from New Zealand deer (Cervus elaphus var. scoticus) velvet antler (NZA,...
Antioxidant Activity and Phenolic Content of Different Parts of Lotus and Optimization of Extraction Condition using Response Surface Methodology

Jang JY, Ahn JH, Jo YH, Hwang BY, Lee MK

  • Nat Prod Sci.
  • 2019 Mar;25(1):44-48.
  • doi: 10.20307/nps.2019.25.1.44
Nelumbo nucifera Gaertn. (Nymphaeaceae) is commonly called lotus and its leaves are widely been used as functional ingredients due to its antioxidant activity. For maximum efficacy, optimized extraction condition was...
Chemical Composition and Antimicrobial Efficiency of Swietenia macrophylla Seed Extract on Clinical Wound Pathogens

Gopalan HK, Md Hanafiah NF, Chean Ring L, Tan WN, Wahidin S, Hway TS, Yenn TW

  • Nat Prod Sci.
  • 2019 Mar;25(1):38-43.
  • doi: 10.20307/nps.2019.25.1.38
Microbial wound infection prolonged the hospitalization and increase the cost for wound management. Silver is commonly used as antimicrobial wound dressing. However, it causes several adverse side effects. Hence, this...
Isolation of Constituents with Nitric Oxide Synthase Inhibition Activity from Phryma leptostachya var. asiatica

Kim D, Lee SK, Park KS, Kwon NY, Park HJ

  • Nat Prod Sci.
  • 2019 Mar;25(1):34-37.
  • doi: 10.20307/nps.2019.25.1.34
Phytochemical studies were performed to identify the active principles of Phryma leptostachya var. asiatica (Phyrymaceae) for anti-inflammation. The anti-inflammatory activity was assessed by measuring the inhibition rate on nitric oxide...
Estrogenic Activity of Sanguiin H-6 through Activation of Estrogen Receptor α Coactivator-binding Site

Trinh TA, Park EJ, Lee D, Song JH, Lee HL, Kim KH, Kim Y, Jung K, Kang KS, Yoo JE

  • Nat Prod Sci.
  • 2019 Mar;25(1):28-33.
  • doi: 10.20307/nps.2019.25.1.28
A popular approach for the study of estrogen receptor α inhibition is to investigate the protein-protein interaction between the estrogen receptor (ER) and the coactivator surface. In our study, we...
Cytotoxic Lactones from the Pericarps of Litsea japonica

Ngo QM, Cao TQ, Woo MH, Min BS

  • Nat Prod Sci.
  • 2019 Mar;25(1):23-27.
  • doi: 10.20307/nps.2019.25.1.23
From the pericarps of Litsea japonica (Thunb.) Jussieu, eighteen butanolide derivatives (1 – 18) were evaluated for their cytotoxic activity against HeLa, HL-60, and MCF-7 cells. Compounds 1 – 9...
Anti-inflammatory Activity of Standardized Fraction from Inula helenium L. via Suppression of NF-κB Pathway in RAW 264.7 Cells

Chun J, Song K, Kim YS

  • Nat Prod Sci.
  • 2019 Mar;25(1):16-22.
  • doi: 10.20307/nps.2019.25.1.16
Inula helenium L. is rich source of eudesmane-type sesquiterpene lactones, mainly alantolactone and isoalantolactone, which have the various pharmacological functions. In this study, we examined the inhibitory effects of nitric...
Chemical Constituents of Bark of Beilschmiedia kunstleri Gamble with Anticancer, Anti-Streptococcus pyogenes, Anti-Bacillus cereus and Anti Plesiomonas shigelloides Activities

Mollataghi A

  • Nat Prod Sci.
  • 2019 Mar;25(1):11-15.
  • doi: 10.20307/nps.2019.25.1.11
Lauraceae is a family medicinal plant whose tubers possesses antimicrobial, and cytotoxic, such as antiparasitic and anti-inflammatory special effects and has been used for the medicine in the cure of...
The Comparison of Seasonal Ginsenoside Composition Contents in Korean Wild Simulated Ginseng (Panax ginseng) which were Cultivated in Different Areas and Various Ages

Yang BW, Lee JB, Lee JM, Jo MS, Byun JK, Kim HC, Ko SK

  • Nat Prod Sci.
  • 2019 Mar;25(1):1-10.
  • doi: 10.20307/nps.2019.25.1.1
The ginsenoside content was compared with wild simulated ginseng (Panax ginseng) collected every season at 11 wild simulated ginseng plantations in Korea. As a result, the total saponin of 7...

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