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Comparative Effects of Dietary Quercetin and Rutin in Rats Fed with the Lieber-DeCarli Ethanol Diet

Seo SJ, Park CH, Ko IY, Jeong YH, Choi YS

  • Nat Prod Sci.
  • 2017 Sep;23(3):222-226.
  • doi: 10.20307/nps.2017.23.3.222
Flavonoids including quercetin and rutin are a group of naturally occurring compounds widely distributed in plants, especially in buckwheat. Thus, cereal and the leaf of the plant have increasingly used...
Phytochemical Constituents from the Rhizomes of Osmunda japonica Thunb and Their Anti-oxidant Activity

Woo KW, Jung JK, Lee HJ, Kim TM, Kim MS, Jung HK, An B, Ham SH, Jeon BH, Cho HW

  • Nat Prod Sci.
  • 2017 Sep;23(3):217-221.
  • doi: 10.20307/nps.2017.23.3.217
Eleven compounds (1–11) were isolated from the rhizomes of Osmunda japonica, and their structures were elucidated based on 1H, 13C-NMR and LC-IT-TOF MS data. Of these compounds, all compounds (1...
A new 3, 4-epoxyfurocoumarin from Heracleum moellendorffii Roots

Park SY, Lee N, Lee S, Kim MJ, Chun W, Kim HP, Yang HJ, Lee HS, Kwon Y

  • Nat Prod Sci.
  • 2017 Sep;23(3):213-216.
  • doi: 10.20307/nps.2017.23.3.213
Activity-guided isolation of Heracleum moellendorffii roots led to four coumarin derivatives as acetylcholinesterase inhibitors. The structures of these isolates were characterized by spectroscopic method to be angelicin (1), isobergapten (2),...
Sesquiterpenoids from the heartwood of Juniperu s chinensis

Jung HJ, Min BS, Jung HA, Choi JS

  • Nat Prod Sci.
  • 2017 Sep;23(3):208-212.
  • doi: 10.20307/nps.2017.23.3.208
A new sesquiterpenoid, 11-hydroxy-valenc-1(10),3(4)-dien-2-one (3), two chemically synthesized but first isolate from nature, 3-oxocedran-8β-ol (1) and valenc-1(10),3(4),11(12)-trien-2-one (2) along with four known compounds, sugiol (4), (+)-nootkatone (5), 11-hydroxy-valenc-1(10)-en-2-one (6), and...
Effects of Nodakenin, Columbianadin, and Umbelliferone Isolated from the Roots of Angelica decursiva on the Gene Expression and Production of MUC5AC Mucin from Human Airway Epithelial NCI-H292 Cells

Lee HJ, Lee CJ

  • Nat Prod Sci.
  • 2017 Sep;23(3):201-207.
  • doi: 10.20307/nps.2017.23.3.201
Angelica decursiva has been utilised as remedy for controlling the airway inflammatory diseases in folk medicine. We investigated whether nodakenin, columbianadin, and umbelliferone isolated from the roots of Angelica decursiva...
Antioxidant and Antiaging Assays of Hibiscus sabdariffa Extract and Its Compounds

Widowati W, Rani AP, Hamzah RA, Arumwardana S, Afifah E, Kusuma HS, Rihibiha D, Nufus H, Amalia A

  • Nat Prod Sci.
  • 2017 Sep;23(3):192-200.
  • doi: 10.20307/nps.2017.23.3.192
Skin aging is a complex biological process due to intrinsic and extrinsic factors. Free radical oxidative is one of extrinsic factors that induce activation of collagenase, elastase and hyaluronidase. Natural...
Luteolin 5-O-glucoside from Korean Milk Thistle, Cirsium maackii, Exhibits Anti-Inflammatory Activity via Activation of the Nrf2/HO-1 Pathway

Jung HA, Roy A, Abdul QA, Kim HR, Park HJ, Choi JS

  • Nat Prod Sci.
  • 2017 Sep;23(3):183-191.
  • doi: 10.20307/nps.2017.23.3.183
Luteolin 5-O-glucoside is the major flavonoid from Korean thistle, Cirsium maackii. We previously reported the anti-inflammatory activities of luteolin 5-O-glucoside in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. In this study, we...
Anti-Helicobacter and Anti-inflammatory Effects of Sohamhyungtang in Helicobacter pylori-Infected Human Gastric Epithelial AGS cells

Won S, Yim D, Choi S

  • Nat Prod Sci.
  • 2017 Sep;23(3):175-182.
  • doi: 10.20307/nps.2017.23.3.175
This study evaluated the anti-Helicobacter and anti-inflammatory effects of Sohamhyungtang (SHHT). The minimum inhibitory concentration (MIC) of SHHT against Helicobacter pylori (H. pylori) was determined by the agar dilution method....
Quercetin Relaxed the Smooth Muscle of Rabbit Penile Corpus Cavernosum by Activating the NO-cGMP Signaling Pathway

Choi BR, Kim HK, Park JK

  • Nat Prod Sci.
  • 2017 Sep;23(3):169-174.
  • doi: 10.20307/nps.2017.23.3.169
The aim of this study was to investigate the effect and action mechanism of quercetin on penile corpus cavernosum smooth muscle (PCCSM). PCCSM precontracted with phenylephrine (Phe) was treated with...
Inhibitory Activity of Cordyceps bassiana Extract on LPS-induced Inflammation in RAW 264.7 Cells by Suppressing NF-κB Activation

Yoon DH, Han C, Fang Y, Gundeti S, Han Lee IS, Song WO, Hwang KC, Kim TW, Sung GH, Park H

  • Nat Prod Sci.
  • 2017 Sep;23(3):162-168.
  • doi: 10.20307/nps.2017.23.3.162
Cordyceps bassiana has long been used as an oriental medicine and reported to possess diverse biological activities. The fruiting bodies of Cordyceps bassiana was extracted with ethanol and then further...
Reserpine treatment activates AMP activated protein kinase (AMPK)

Park R, Lee KI, Kim H, Jang M, Ha TK, Oh WK, Park J

  • Nat Prod Sci.
  • 2017 Sep;23(3):157-161.
  • doi: 10.20307/nps.2017.23.3.157
Reserpine is a well-known medicine for the treatment of hypertension, however the role of reserpine in cell signaling is not fully understood. Here, we report that reserpine treatment induces the...
New Azafluorenone Derivative and Antibacterial Activities of Alphonsea cylindrica Barks

Talip MA, Azziz SS, Wong CF, Awang K, Naz H, Bakri YM, Ahmad MS, Litaudon M

  • Nat Prod Sci.
  • 2017 Sep;23(3):151-156.
  • doi: 10.20307/nps.2017.23.3.151
A phytochemical study of Alphonsea cylindrica King (unreported) has led to the isolation of six alkaloids. The compounds were identified as kinabaline (1; azafluorenone alkaloid), muniranine (2), O-methylmoschatoline (3; oxoaporphine...

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