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Vestibular Histopathology in Temporal Bone

Nam SI

There are a number of reports on the pathologies of vestibular disorders. However, these studies included only a few examples, which were not quantitative but merely anecdotal or descriptive. However,...
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Foreign Body of External Auditory Canal: Review of 170 Cases

Koo BM, Park JW, Bae KH, Lee YW, Park SH, Jeong JI, Nam SI

BACKGROUND AND OBJECTIVES: Foreign bodies in the external auditory canal (EAC) are frequently encountered by otolaryngologists, emergency care physicians and pediatricians. The purpose of this study was to assess clinical...
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Bacterial Meningitis Initially Presenting as Labyrinthitis

Koo BM, Nam SI, Park SH

Labyrinthitis causes damage to inner ear structure, and in turn hearing loss and vertigo. Labyrinthitis is classified as otogenic labyrinthitis and meningogenic labyrinthitis. Otogenic labyrinthitis can be diagnosed early through...
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Recent Research Trend for Ménière's Disease

Nam SI

Ménière's disease is a poorly understood disorder of the inner ear characterized by intermittent episodic vertigo, fluctuating hearing loss, ear fullness and tinnitus. In this paper, we present a review...
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The Value of PROPELLER Diffusion-Weighted Image in the Detection of Cholesteatoma

Park SH, Lee YW, Park JW, Jang HJ, Nam SI

BACKGROUND AND OBJECTIVES: This study was to done to determine the value of PROPELLER diffusion-weighted imaging in detecting cholesteatoma. SUBJECTS AND METHOD: Sixty-five patients were evaluated by preoperative magnetic resonance imaging...
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Vestibular Paroxysmia Mimicking Benign Parxysmal Positional Vertigo

Cho HK, Lee YW, Park SH, Nam SI

Vestibular paroxysmia is the name given to the syndrome caused by vascular compression of the vestibulocochlear nerve. The main symptoms of vestibular paroxysmia are recurrent, spontaneous, brief attacks of spinning,...
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Medications as Risk Factor for Falls

Lee YW, Nam SI

Falls are the most common cause of accidents among the older population, leading to both fatal and non-fatal injuries. Falls is a syndrome resulting from the cumulative effect of various...
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A Case of Two Isolated Congenital Cholesteatomas Presented in Middle Ear Cavity

Kim TH, Cho HK, Park SH, Nam SI

Middle ear cholesteatoma is considered to be congenital in origin when there is an intact tympanic membrane with no prior history of otorrhea, tympanic perforation or otologic procedure. However, congenital...
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Objective Tinnitus Concomitant with Eye Blinking: A Case Report

Kim TH, Jang HJ, Park SH, Nam SI

Tinnitus is a common auditory phenomenon associated with many otological diseases, and is usually subjective. Objective tinnitus can be generated by para-auditory structures, usually derived from vascular or myogenic sources,...
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Dicer Is Down-regulated and Correlated with Drosha in Idiopathic Sudden Sensorineural Hearing Loss

Kim S, Lee JH, Nam SI

Previously, we reported the expression levels of specific microRNA machinery components, DGCR8 and AGO2, and their clinical association in patients with idiopathic sudden hearing loss (SSNHL). In the present study,...
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The Expression of AGO2 and DGCR8 in Idiopathic Sudden Sensorineural Hearing Loss

Han SY, Kim S, Shin DH, Cho JH, Nam SI

OBJECTIVES: The microRNAs have been implicated in the development and function of the inner ear, especially in contribution to hearing. However, the impact of idiopathic sudden sensorineural hearing loss (SSNHL)...
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Dexamethasone Inhibits Interleukin-1beta-Induced Matrix Metalloproteinase-9 Expression in Cochlear Cells

Nam SI, Kwon TK

OBJECTIVES: To investigate the effect of interleukin (IL)-1beta on matrix metalloproteinase (MMP)-9 expression in cochlea and regulation of IL-1beta-mediated MMP-9 expression by dexamethasone and the molecular and signaling mechanisms involved. METHODS:...
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The Role of Vestibular Function Tests in Patients with Sudden Sensorineural Hearing Loss Who Have Subclinical Vestibular Dysfunction

Jung SG, Park JW, Han SY, Park SH, Nam SI

BACKGROUND AND OBJECTIVES: The evaluation of vestibular function is very important for patients with sudden sensorineural hearing loss (SNHL) as it is a well-known prognostic factor. The purpose of this...
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Multicenter Study on the Clinician's Diagnostic and Therapeutic Approaches for Benign Paroxysmal Positional Vertigo in Korea

Jeon EJ, Chung WH, Choi JH, Nam EC, Park HJ, Lee JD, Lee WS, Kim KS, Goh EK, Koo JW, Kim MB, Kim MB, Kim SH, Kim YJ, Kim CH, Nam SI, Mun SK, Park GY, Park SY, Park SN, Bae CH, Boo SH, Suh MW, Seo JH, Son EJ, Song JJ, Song JJ, Shin JW, Shim DB, Ahn SK, Youm HY, Yoo SY, Lee DH, Lee SH, Lee CH, Lee HS, Lee HH, Lee HJ, Choung YH, Choi SH, Choi JS, Hong SM, Hong SK

  • KMID: 2316798
  • Res Vestib Sci.
  • 2013 Sep;12(3):79-92.
BACKGROUND AND OBJECTIVES: It is necessary to establish the most efficient diagnostic and therapeutic method for benign paroxysmal positional vertigo (BPPV), which is appropriate for Korean healthcare system. We aimed...
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Benign Paroxysmal Positional Vertigo After Cochlear Implantation

Park JW, Park MJ, Lee YW, Nam SI

  • KMID: 1426908
  • Res Vestib Sci.
  • 2013 Mar;12(1):35-38.
Cochlear implantation (CI) has enabled hearing rehabilitation of patients with severe hearing impairment for more than 20 years now. There have been reported that one possible complication of CI is...
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Endolymphatic Hydrops: Pathophysiology and Etiology

Nam SI

Endolymphatic hydrops (EH) represents a histopathologic finding in which the structures bounding the endolymphatic space are distended by an enlargement of endolymphatic volume. EH primarily involves the cochlear duct and...
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Characterization of Gentamicin-Induced Apoptosis in a Cochlear Cell Model

Nam SI, Song DK, Park SH, Lee JH, Lee WK, Kim EM, Park JS

BACKGROUND AND OBJECTIVES: Aminoglycoside antibiotics are ototoxic. Understanding of the molecular mechanisms underlying the drug-induced ototoxicity, however, has been hampered by limited cell availability. Recently, HEI-OC1 cells, which are of...
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Staging in Vestibular Schwannoma Surgery: A Modified Technique

Kim E, Nam SI

The authors herein propose the staged excision as a novel strategy to preserve facial nerve and minimize complication during microsurgery of large vestibular schwannoma (VS). At the first stage, for...
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New Technique for Surgery of Petrous Apex Cholesterol Granuloma

Kim EM, Nam SI

  • KMID: 2118527
  • J Korean Neurosurg Soc.
  • 2007 May;41(5):347-351.
The authors present a new technique for surgery of cholesterol granuloma (CG) at the petrous apex. An epidural middle fossa approach is used to expose and remove the cyst, with...
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Single Nucleotide Polymorphism of Tumor Necrosis Factor-Alpha Gene with Sudden Deafness in Korean Population

Joo MD, Tak KH, Lee DH, Yoo KI, Chung IS, Nam SI, Lee MY, Shin DH, Kim TW

  • KMID: 1511755
  • Korean J Aerosp Environ Med.
  • 2006 Dec;16(3):41-48.
BACKGROUND: Infections and vascular disorders are the two most widely accepted probable causes of sudden hearing loss. Tumor necrosis factor alpha (TNF-alpha) is major pro-inflammatory cytokine that is thought to...
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