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The Effect of Capsaicin on Neuroinflammatory Mediators of Rosacea

Kim HB, Na EY, Yun SJ, Lee JB

Background: Rosacea is a chronic inflammatory skin disease with a pathophysiological mechanism that remains unclear. Recently, dysregulation of the sensory nerve system has been implicated in the development of this...
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Protoporphyrin IX Synthesis Induced by 5-aminolevulinic Acid and Its Esters in Normal Mouse Skin

Kim HS, Na EY, Yun SJ, Kim SJ, Lee SC, Won YH, Park HR, Lee JB

  • KMID: 2247815
  • Korean J Dermatol.
  • 2009 Jun;47(6):683-689.
BACKGROUND: Photodynamic therapy with using 5-aminolevulinic acid (ALA) is a good noninvasive treatment modality that can treat several cutaneous diseases. Yet hydrophilic ALA is not able to easily penetrate the...
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Identification of Zinc Finger Genes that are Differentially Expressed upon Apoptosis of Ramos B Cells

Shin MS, Kim SY, Dong SM, Na EY, Lee SH, Park WS, Lee JY, Yoo NJ

  • KMID: 2275698
  • Korean J Pathol.
  • 1998 Dec;32(12):1043-1048.
Typical programmed cell death requires de novo macromolecular synthesis and shares common morphological changes referred to as apoptosis. To elucidate the molecular mechanism of apoptosis, we isolated 13 cDNA clones...
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Identification of Differentially Expressed Genes Using RNA Fingerprinting in Cell after DNA Damage

Lee JY, Shin MS, Dong SM, Na EY, Kim SY, Lee SH, Park WS, Yoo NJ

  • KMID: 1725385
  • Korean J Pathol.
  • 1998 May;32(5):321-327.
RNA fingerprinting using on arbitrary primed polymerase chain reaction (RAP-PCR) was carried out to identify differentially expressed genes in HL-60 cell after treatment of methylmethane sulfonate (MMS). Twenty differentially expressed...
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In vitro Study and Clinical Trial of Natural Essential Oils and Extract Against Malassezia Species

Lee MY, Na EY, Yun SJ, Lee SC, Won YH, Lee JB

BACKGROUND: Malassezia, a lipophilic yeast, is a causative agent for dandruff and seborrheic dermatitis. Many biological agents have been studied for anti-Malassezia effect but further studies are needed for their...
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Citron Essential Oils Alleviate the Mediators Related to Rosacea Pathophysiology in Epidermal Keratinocytes

Jeon HW, Na EY, Yun SJ, Lee SC, Lee JB

BACKGROUND: Citron is well known for an abundance of antioxidative and anti-inflammatory ingredients such as vitamin C, polyphenol compounds, flavonoids, and limonoids. OBJECTIVE: In this study, we aimed to evaluate the...
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Ethnic Differences of the p53 Genetic Alteration in Cutaneous Malignant Melanoma

Park WS, Na EY, Lee SK, Lee SH, Kim SY, Kang SJ, Song KY, Nam SW, Yoo NJ, Lee JY

  • KMID: 2275647
  • Korean J Pathol.
  • 2001 Apr;35(2):158-164.
BACKGROUND: There are significant differences in the clincopathologic pattern including the incidence, favor site, and histopathologic type between cutaneous malignant melanomas arising from whites, asians and blacks. These differences might...
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The Role of gadd and p53 Genes in Apoptosis and Cell Cycle Delay by Genotoxic Agents

Lee JY, Lee JD, Dong SM, Na EY, Shin MS, Kim SY, Lee SH, Park WS, Yoo NJ

  • KMID: 2037280
  • Korean J Pathol.
  • 1998 Apr;32(4):239-247.
The aim of this study was to investigate the relationships between the gadd genes expression and an apoptosis induction in two different growing cell types after treatments with cisplatin and...
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