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Moderating Effect of Physical Activity on the Relationship between Perceived Stress and Depression in Patients with Ischemic Heart Disease: A Cross-Sectional Study

Yeom YH, Lee SJ

Purpose: This study was conducted to investigate the moderating effect of physical activity on the relationship between perceived stress and depression in patients newly diagnosed with ischemic heart disease. Methods:...
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LOXL1-AS1 Aggravates Myocardial Ischemia/Reperfusion Injury Through the miR-761/PTEN Axis

He W, Duan L, Zhang L

Background and Objectives: Myocardial ischemia and reperfusion injury (MIRI) has high morbidity and mortality worldwide. We aimed to explore the role of long noncoding RNA lysyl oxidase like 1 antisense...
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Consensus Document on Perioperative Antithrombotic Management: Part 2. Case Study

Park Y, Her AY, Kim HK, Moon JY, Park JH, Park KH, Lee KH, Joo HJ, Won HY, Ahn SG, Park HJ, Hong SJ, Kim BJ, Ban SP, Suh JW, Song YB, Cho JR, Jeong YH, Kim W, Shin ES, on behalf of Platelet-Thrombosis Research Group, Korean Society of Interventional Cardiology

Given the progressive improvements in antithrombotic strategies, management of cardiovascular disease has become sophisticated/refined. However, the optimal perioperative management of antithrombotic therapy in patients with acute coronary syndrome or who...
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Consensus Document on Perioperative Antithrombotic Management: Part 1. A Review

Park Y, Her AY, Kim HK, Moon JY, Park JH, Park KH, Lee KH, Joo HJ, Won HY, Ahn SG, Park HJ, Hong SJ, Kim BJ, Ban SP, Suh JW, Song YB, Cho JR, Jeong YH, Kim W, Shin ES, on behalf of Platelet-Thrombosis Research Group, Korean Society of Interventional Cardiology

The prevalence of ischemic heart disease is steadily growing as populations age. Antithrombotic treatment is a key therapeutic modality for the prevention of secondary cerebro-cardiovascular disease. Patients with acute coronary...
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Therapeutic hypothermia for acute myocardial infarction: a narrative review of evidence from animal and clinical studies

Jung KT, Bapat A, Kim YK, Hucker WJ, Lee K

Myocardial infarction (MI) is the leading cause of death from coronary heart disease and requires immediate reperfusion therapy with thrombolysis, primary percutaneous coronary intervention, or coronary artery bypass grafting. However,...
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Predictors of health-related quality of life in Koreans with cardiovascular disease

Lim JH

Objectives: This study aimed to identify the predictors of health-related quality of life (HRQoL) in Korean adults with cardiovascular disease (CVD). Methods: This was a cross-sectional study with a stratified...
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Functional Angioplasty: Definitions, Historical Overview, and Future Perspectives

Park H, Kang DY, Lee CW

Percutaneous coronary intervention (PCI) is used to treat obstructive coronary artery disease (CAD). The role of PCI is well defined in acute coronary syndrome, but that for stable CAD remains...
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Factors Influencing Smoking Cessation Behavior in Patients with Ischemic Heart Disease Following Coronary Angiography

Kim M, Moon Y

Purpose: The purpose of this study was to elucidate the relationship between readiness to quit smoking and smoking cessation, and identify factors associated with smoking cessation in smokers with ischemic...
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Diagnostic Approach to Angina Pectoris

Ahn JH, Hong YJ

Stable angina is a chronic, systemic disease with a wide range of associated symptoms and clinical outcomes. Prompt diagnosis can be challenging for clinicians. Typical chest pain caused by stable...
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Association of Quantitative Flow Ratio with Lesion Severity and Its Ability to Discriminate Myocardial Ischemia

Dai N, Hwang D, Lee JM, Zhang J, Tong Y, Jeon KH, Paeng JC, Cheon GJ, Koo BK, Ge J

Background and Objectives: Quantitative flow ratio (QFR) is an angiography-based technique for functional assessment of coronary artery stenosis. This study investigated the response of QFR to different degree of stenosis...
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Clinical and Hospital Factors Affecting Treatment with Primary Prevention Implantable CardioverterDefibrillators in Ischemic Cardiomyopathy Patients

Lee JH, Yu HT, Oh IY, Choi EK, Sung JH, Lee YS, Kim JY, Baek Y, Park J, Joung B, ADVANCE-ICM investigators

Purpose: Implantable cardioverter defibrillators (ICD) are the standard of care for primary prevention (PP) in patients with ischemic cardiomyopathy (ICM). However, PP ICD implantation is underused in Asian countries. This...
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Long-term Patient Prognostication by Coronary Flow Reserve and Index of Microcirculatory Resistance: International Registry of Comprehensive Physiologic Assessment

Lee JM, Choi KH, Doh JH, Nam CW, Shin ES, Hoshino M, Murai T, Yonetsu T, Mejía-Rentería H, Kakuta T, Escaned J, Koo BK

Background and Objectives: Recent guideline recommends evaluation using of coronary flow reserve (CFR) and index of microcirculatory resistance (IMR) in patients with functionally insignificant stenosis. We evaluated clinical implications of...
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The Impact of Depression on Cardiovascular Disease: A Nationwide Population-Based Cohort Study in Korean Elderly

Park DH, Cho JJ, Yoon JL, Kim MY, Ju YS

Background: Depression is suggested to be associated with cardiovascular disease, including ischemic heart disease and cerebrovascular disease. This study investigated the impact of depression on cardiovascular disease in the elderly...
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What Do We Currently Knowand Not Know about CoronaryCT Angiography?

Hoe J

This review paper summarises our current state of knowledge on the use of coronary CT angiography(CCTA) for assessing coronary stenosis, use of anatomical CCTA combined withfunctional CT to assess for...
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Human Recombinant Apyrase Therapy Protects Against Myocardial Ischemia/Reperfusion Injury and Preserves Left Ventricular Systolic Function in Rats, as Evaluated by 7T Cardiovascular Magnetic Resonance Imaging

Xu Z, Chen W, Zhang R, Wang L, Chen R, Zheng J, Gao F

Objective: The occurrence of intramyocardial hemorrhage (IMH) and microvascular obstruction (MVO) in myocardial infarction (MI), known as severe ischemia/reperfusion injury (IRI), has been associated with adverse remodeling. APT102, a soluble...
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Evaluation of Myocardial Ischemia Using Coronary Computed Tomography Angiography in Patients with Stable Angina

Ko SM

Assessment of myocardial ischemia in patients with stable angina is important in deciding whether to treat coronary artery disease and in predicting clinical outcome. The fractional flow reserve is a...
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Effect of gemigliptin on cardiac ischemia/reperfusion and spontaneous hypertensive rat models

Nam DH, Park J, Park SH, Kim KS, Baek EB

Diabetes is associated with an increased risk of cardiovascular complications. Dipeptidyl peptidase-4 (DPP-IV) inhibitors are used clinically to reduce high blood glucose levels as an antidiabetic agent. However, the effect...
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The Role of Glucagon-Like Peptide 1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors in Reducing Cardiovascular Events in Patients with Type 2 Diabetes

Kim GS, Park JH, Won JC

The prevalence of type 2 diabetes mellitus (T2DM), which is associated with cardiovascular morbidity and mortality, is increasing worldwide. Although there have been advances in diabetes treatments that reduce microvascular...
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Associated Factors of Ischemic Heart Disease Identified Among Post-Menopausal Women

Ra JS, Kim HS, Jeong YH

OBJECTIVES: This study identifies associated factors of ischemic heart disease (IHD) among post-menopausal Korean women at the biomedical (age, family history of hypertension, dyslipidemia, type 2 diabetes mellitus, or cerebro-cardiovascular...
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Non-fasting triglyceride levels in the Korean population with and without ischemic heart disease and cerebrovascular disease

Lee SY, Koo BK, Moon MK

BACKGROUND/AIMS: Associations between non-fasting triglyceride (TG) levels and a risk of ischemic heart disease (IHD) and cerebrovascular accident (CVA) have been suggested in Caucasians. We aimed to investigate whether non-fasting...
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