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Efficacy of L-carnitine on ribavirin-induced hemolytic anemia in patients with hepatitis C virus infection

Sato S, Moriya K, Furukawa M, Saikawa S, Namisaki T, Kitade M, Kawaratani H, Kaji K, Takaya H, Shimozato , Sawada Y, Seki K, Kitagawa K, Akahane T, Mitoro A, Okura Y, Yamao J, Yoshiji H

BACKGROUND/AIMS: L-carnitine not only alleviates hyperammonemia and reduces muscle cramps in patients with liver cirrhosis, but also improves anemia in patients with chronic hepatitis and renal dysfunction. This study prospectively...
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Elucidation of the pathophysiology of intradialytic muscle cramps: pharmacokinetics applied to translational research

Atkinson A

In the conventional concept of translational research, investigations flow from the laboratory bench to the bedside. However, clinical research can also serve as the starting point for subsequent laboratory investigations...
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Rheumatoid arthritis accompanied by Gitelman syndrome

Park MG, Lee JH, Kim SJ, Park SH, Park SK, Choi JS, Hwang JY

Gitelman syndrome is a condition caused by a mutation of the thiazide sensitive Na-Cl cotransporter gene on the distal convoluted tubule. It results in a variety of clinical features, including...
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A Case of Pseudohypoparathyroidism Type Ib Caused by Aberrant Methylation in the GNAS Complex Locus

Jo SJ, Han E, Jang W, Chae H, Kim Y, Lee GD, Cho WK, Suh BK, Kim M

Pseudohypoparathyroidism (PHP) is a rare disorder caused by genetic and epigenetic aberrations in the GNAS complex locus resulting in impaired expression of stimulatory G protein (Gsα). PHP type Ib (PHP-Ib)...
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Management Dilemma in Olanzapine Induced Restlessness and Cramps in Legs

Kar SK, Singh A

No abstract available.
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A Retrospective Study of Long Acting Risperidone Use to Support Treatment Adherence in Youth with Conduct Disorder

Demirkaya , Aksu H, Özgür BG

OBJECTIVE: Risperidone has been widely used to control aggression and conduct disorder (CD) in youth; however, treatment compliance is a major problem in CD. Our aim is to evaluate the...
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Chemical colitis caused by hydrogen peroxide enema in a child: case report and literature review

Lee JS, Yoo JK

A 2-year-old girl, previously healthy, was brought to the emergency department because of significant cramping abdominal pain with recurrent hematochezia after an accidental hydrogen peroxide enema (35%, 5 mL) by...
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Adjuvant Teriparatide Therapy for Surgical Treatment of Femoral Fractures; Does It Work?

Kim JT, Jeong HJ, Lee SJ, Kim HJ, Yoo JJ

PURPOSE: Atypical femoral fracture (AFF), periprosthetic femoral fracture (PPFF) and femoral nonunion (FNU) are recalcitrant challenges for orthopedic surgeons. Teriparatide (TPTD) had been demonstrated to have anabolic effects on bone...
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A Systematic Review on Drug Safety for Molsidomine, Nicorandil and Trimetazidine

Jeong KH, Lee E

BACKGROUND: Ischemic heart disease is the most common type of heart disease and an important cause of death in Korea. Among marketed anti-anginal medications, molsidomine, nicorandil, and trimetazidine are approved...
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Precise Muscle Selection Using Dynamic Polyelectromyography for Treatment of Post-stroke Dystonia: A Case Report

Jung TM, Kim AR, Lee Y, Kim DH, Kim DY

Dystonia has a wide range of causes, but treatment of dystonia is limited to minimizing the symptoms as there is yet no successful treatment for its cause. One of the...
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Rapid Progression of Sporadic ALS in a Patient Carrying SOD1 p.Gly13Arg Mutation

Kim MJ, Bae JH, Kim JM, Kim HR, Yoon BN, Sung JJ, Ahn SW

Amyotrophic lateral sclerosis (ALS), the most common adult onset motor neuron disease, is pathologically characterized by progressive loss of the upper and lower motor neurons. Mutations in the Cu/Zn superoxide...
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A novel mutation of CLCNKB in a Korean patient of mixed phenotype of Bartter-Gitelman syndrome

Cho HW, Lee ST, Cho H, Cheong HI

Bartter syndrome (BS) is an inherited renal tubular disorder characterized by low or normal blood pressure, hypokalemic metabolic alkalosis, and hyperreninemic hyperaldosteronism. Type III BS is caused by loss-of-function mutations...
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Clinical and Genetic Characterization of Female Dystrophinopathy

Lee SH, Lee JH, Lee KA, Choi YC

BACKGROUND AND PURPOSE: Duchenne and Becker muscular dystrophies are the most common X-linked recessive muscular dystrophies. Dystrophin gene mutations usually affect men, but reportedly 2.5-7.8% of women are affected and...
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Severe hyponatremia and seizures after bowel preparation with low-volume polyethylene glycol plus ascorbic acid solution

Lee JY, Jang BI, Nam YJ, Song J, Kim MC, Chung SM, Jang JG, Cho JH

The widely used polyethylene glycol (PEG)-based solutions have been proven effective for bowel preparation when 4 L of the solution is administered before colonoscopy. However, large volumes of the solutions...
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Practice patterns in the management of threatened preterm labor in Korea: A multicenter retrospective study

Hwang HS, Na SH, Hur SE, Lee SA, Lee KA, Cho GJ, Oh KY, Jin CH, Lee SM, Shin JE, Park KH, Lim JY, Choi SJ, Lee JH, Choi SK, Shim JY, Jo YS, Choi GY, Kim YH, Kil KC, Kim JW, Kwak DW, Kang YD, Kim YJ

OBJECTIVE: This study aimed to examine clinical practice patterns in the management of pregnant women admitted with threatened preterm labor (TPL) in Korea. METHODS: Data from women admitted with a diagnosis...
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The Overlap between Fibromyalgia Syndrome and Myotonia Congenita

Nam TS, Choi SY, Park DJ, Lee SS, Kim YO, Kim MK

BACKGROUND: Fibromyalgia syndrome (FMS) is a complex disorder characterized by chronic widespread pain (CWP), multiple areas of tenderness, sleep disturbance, fatigue, and mood or cognitive dysfunction. Myotonia congenita (MC) is...
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Use of lenalidomide in the management of relapsed or refractory multiple myeloma: expert recommendations in Korea

Kim HJ, Yoon SS, Eom HS, Kim K, Kim JS, Lee JJ, Bang SM, Min CK, Park JS, Lee JH, Korean Multiple Myeloma Working Party

Multiple myeloma (MM) is the third most common hematologic malignancy in Korea. Historically, the incidence of MM in Korea has been lower than that in Western populations, although there is...
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Decompression of the Sciatic Nerve Entrapment Caused by Post-Inflammatory Scarring

Son BC, Kim DR, Jeun SS, Lee SW

A rare case of chronic pain of entrapment neuropathy of the sciatic nerve successfully relieved by surgical decompression is presented. A 71-year-old male suffered a chronic right buttock pain of...
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A Rare Manifestation of Hypothyroid Myopathy: Hoffmann's Syndrome

Lee KW, Kim SH, Kim KJ, Kim SH, Kim HY, Kim BJ, Kim SG, Choi DS

Hypothyroid myopathy is observed frequently and the resolution of the clinical manifestations of myopathy following thyroid hormone replacement is well known. However, a specific subtype of hypothyroid myopathy, Hoffmann's syndrome,...
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Sleep Disorder Caused by Proctalgia Fugax

Kim KH, Cho KH, Cho YJ, Heo K

Proctalgia fugax is characterized by severe cramp like pain in anorectal area. It is a common functional gastrointestinal disorder, but symptoms of proctalgia fugax are usually too brief and mild...
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