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Optimization of Microenvironments Inducing Differentiation of Tonsil-Derived Mesenchymal Stem Cells into Endothelial Cell-Like Cells

Oh SY, Choi DH, Jin YM, Yu Y, Kim HY, Kim G, Park YS, Jo I

BACKGROUND: Stem cell engineering is appealing consideration for regenerating damaged endothelial cells (ECs) because stem cells can differentiate into EC-like cells. In this study, we demonstrate that tonsil-derived mesenchymal stem...
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Application of Developmental Principles for Functional Regeneration of Salivary Glands

Lee ES, Adhikari N, Jung JK, An CH, Kim JY, Kim JY

Currently, there has been rapid increase in the studies about salivary production because of the hyposalivation, xerostomia, caused by radiotherapy for head and neck cancer, Sjogren syndrome and aging. An...
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Ossification of the Triradiate Cartilage and Posterior Acetabulum

Kim SH, Yoon HK, Han H, Cho S, Seo YK

PURPOSE: This study attempts to evaluate the skeletal maturation patterns of the triradiate cartilage (TRC) and the posterior acetabular wall (PA), which can be easily assessed on body computerized tomography...
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Generation of novel hyaluronic acid biomaterials for study of pain in third molar intervention: a review

Shuborna N, Chaiyasamut T, Sakdajeyont W, Vorakulpipat C, Rojvanakarn M, Wongsirichat N

Hyaluronic acid (HA) has long been studied in diverse applications. It is a naturally occurring linear polysaccharide in a family of unbranched glycosaminoglycans, which consists of repeating di-saccharide units of...
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Scanning electron microscopy of filiform papillae development in Korean native goats (Capra hircus)

Lee SJ, Cho GH, Kim MK, Kim CS, Won CK

The aim of this study was to investigate morphological development of filiform papillae (FP) in Korean native goats by using scanning electron microscopy. Tongues were removed from goat fetuses (days...
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Development of the Three-Dimensional Perfusion Culture Technology for the Salivary Ductal Cells

Kim JW, Kim JM, Choi JS

BACKGROUND AND OBJECTIVES: Salivary hypofunction is one of the common side effects after radioiodine therapy, and its pathophysiology is salivary ductal stenosis resulting from ductal cell injury. This study aimed...
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Genome-Wide Association Studies Associated with Backfat Thickness in Landrace and Yorkshire Pigs

Lee YS, Shin D

Although pork quality traits are important commercially, genome-wide association studies (GWASs) have not well considered Landrace and Yorkshire pigs worldwide. Landrace and Yorkshire pigs are important pork-providing breeds. Although quantitative...
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Troglitazone Inhibits Matrix Metalloproteinase-9 Expression and Invasion of Breast Cancer Cell through a Peroxisome Proliferator-Activated Receptor γ-Dependent Mechanism

Hong OY, Youn HJ, Jang HY, Jung SH, Noh EM, Chae HS, Jeong YJ, Kim W, Kim CH, Kim JS

PURPOSE: Peroxisome proliferator-activated receptor γ (PPARγ) is involved in the pathology of numerous diseases including atherosclerosis, diabetes, obesity, and cancer. Matrix metalloproteinases (MMPs) play a significant role in tissue remodeling...
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Coactosin-like protein 1 inhibits neuronal migration during mouse corticogenesis

Li G, Yin Y, Chen J, Fan Y, Ma J, Huang Y, Chen C, Dai P, Chen S, Zhao S

Coactosin-like protein 1 (Cotl1), a member of the actin-depolymerizing factor (ADF)/cofilin family, was first purified from a soluble fraction of Dictyostelium discoideum cells. Neuronal migration requires cytoskeletal remodeling and actin...
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Identification of the PROM1 Mutation p.R373C in a Korean Patient With Autosomal Dominant Stargardt-like Macular Dystrophy

Kim JM, Lee C, Lee GI, Kim NK, Ki CS, Park WY, Kim BJ, Kim SJ

Stargardt-like macular dystrophy 4 (STGD4) is a rare macular dystrophy characterized by bull's eye atrophy of the macula and the underlying retinal pigment epithelium. Patients with STGD4 show decreased central...
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Comprehensive Transcriptome Profiling of Balding and Non-Balding Scalps in Trichorhinophalangeal Syndrome Type I Patient

Kim YJ, Yoon B, Han K, Park BC

BACKGROUND: Trichorhinophalangeal syndrome (TRPS) patients tend to have alopecia that appears to be androgenetic, and this genetic model might give clues to the pathogenesis of hair loss or hair morphogenesis. OBJECTIVE:...
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The Role of Autonomous Wntless in Odontoblastic Differentiation of Mouse Dental Pulp Cells

Choi H, Kim TH, Ko SO, Cho ES

PURPOSE: Wnt signaling plays an essential role in the dental epithelium and mesenchyme during tooth morphogenesis. Deletion of the Wntless (Wls) gene in odontoblasts appears to reduce canonical Wnt activity,...
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Extracellular Matrix Revisited: Roles in Tissue Engineering

Kim Y, Ko H, Kwon IK, Shin K

  • KMID: 2309836
  • Int Neurourol J.
  • 2016 May;20(Suppl 1):S23-S29.
The extracellular matrix (ECM) is a heterogeneous, connective network composed of fibrous glycoproteins that coordinate in vivo to provide the physical scaffolding, mechanical stability, and biochemical cues necessary for tissue...
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Development and Growth of the Normal Cranial Vault : An Embryologic Review

Jin SW, Sim KB, Kim SD

Understanding the development of a skull deformity requires an understanding of the normal morphogenesis of the cranium. Craniosynostosis is the premature, pathologic ossification of one or more cranial sutures leading...
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Synthetic Hydrogels with Stiffness Gradients for Durotaxis Study and Tissue Engineering Scaffolds

Whang M, Kim J

Migration of cells along the right direction is of paramount importance in a number of in vivo circumstances such as immune response, embryonic developments, morphogenesis, and healing of wounds and...
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Nfic regulates tooth root patterning and growth

Kim TH, Bae CH, Yang S, Park JC, Cho ES

Molecular interactions between epithelium and mesenchyme are important for root formation. Nuclear factor I-C (Nfic) has been identified as a key regulator of root formation. However, the mechanisms of root...
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Noncompaction of Ventricular Myocardium Involving the Right Ventricle

Saglam M, Saygin H, Kozan H, Ozturk E, Mutlu H

Noncompaction ventricular myocardium is an unusual cause of cardiomyopathy. It is association with congenital heart defects, most often with outflow obstructive lesions or coronary anomalies. However, no factor could explain...
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Gene Expression Profiling by Microarray during Tooth Development of Rats

Yoo HI, Shim HK, Kim SH

Odontogenic cells express many genes spatiotemporally through complex and intricate processes during tooth formation. Therefore, investigating them during the tooth development has been an important subject for the better understanding...
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Extracellular Matrix Metalloproteinase Inducer is Regulated Developmentally and Functionally in the Rat Submandibular Gland

Yoo HI, Suh HY, Kim SH

The salivary gland undergoes complex process of growth and differentiation of the branching morphogenesis of ductal system during the prenatal and early postnatal periods which are regulated by various elements...
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COMP-Ang1 Potentiates EPC Treatment of Ischemic Brain Injury by Enhancing Angiogenesis Through Activating AKT-mTOR Pathway and Promoting Vascular Migration Through Activating Tie2-FAK Pathway

Moon HE, Byun K, Park HW, Kim JH, Hur J, Park JS, Jun JK, Kim HS, Paek SL, Kim IK, Hwang JH, Kim JW, Kim DG, Sung YC, Koh GY, Song CW, Lee B, Paek SH

Successful recovery from brain ischemia is limited due to poor vascularization surrounding the ischemic zone. Cell therapy with strong angiogenic factors could be an effective strategy to rescue the ischemic...
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