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Sodium butyrate inhibits high glucose-induced inflammation by controlling the acetylation of NF-κB p65 in human monocytes

Moon HR, Yun JM

BACKGROUND/OBJECTIVES: Hyperglycemia is a major cause of diabetes and diabetesrelated diseases. Sodium butyrate (NaB) is a short-chain fatty acid derivative that produces dietary fiber by anaerobic bacterial fermentation in the...
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MHY2251, a New SIRT1 Inhibitor, Induces Apoptosis via JNK/p53 Pathway in HCT116 Human Colorectal Cancer Cells

Kang YJ, Kwon YH, Jang JY, Lee JH, Lee S, Park Y, Moon HR, Chung HY, Kim ND

Sirtuins (SIRTs) belong to the nicotinamide adenine dinucleotide (NAD+)-dependent class III histone deacetylase family. They are key regulators of cellular and physiological processes, such as cell survival, senescence, differentiation, DNA...
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Effect of the Recombinant Human Epidermal Growth Factor Ointment on Cutaneous Surgical Wounds Compared to Antibiotic Ointment

Ryu SI, Kim KE, Jeong JY, Park Jh, Moon HR, Kim IH

Background: Applying antibiotic ointment after skin surgery can decrease infection and improve scar. Epidermal growth factor (EGF) is known to be able to promote the growth and movement of epidermal...
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Clinico-Dermoscopic Features of Atypical Dermatofibroma

Oh H, Moon HR, Ryu HJ, Kim IH

  • KMID: 2517076
  • Korean J Dermatol.
  • 2021 Jun;59(5):341-347.
Background: Dermatofibroma is a common benign skin neoplasm that is usually easy to recognize; however, in some cases, it is difficult to differentiate it from atypical dermatofibroma. Atypical dermatofibroma is...
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Dermoscopic Findings and the Clinicopathologic Correlation of Pigmented Purpuric Dermatosis: A Retrospective Review of 60 Cases

Kim KE, Moon HR, Ryu HJ

Background: Pigmented purpuric dermatosis (PPD) is known as a chronic recurrent eruption which usually presents with petechiae and pigmented macules on the lower extremities. Dermoscopy is a noninvasive diagnostic tool in...
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A Case of Eccrine Porocarcinoma, Misdiagnosed in Initial Biopsy but Diagnosed with Re-Examination by Dermoscopy

Oh H, Moon HR, Kim IH

  • KMID: 2516148
  • Korean J Dermatol.
  • 2021 May;59(4):314-320.
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Novel SIRT Inhibitor, MHY2256, Induces Cell Cycle Arrest, Apoptosis, and Autophagic Cell Death in HCT116 Human Colorectal Cancer Cells

Kim MJ, Kang YJ, Sung B, Jang JY, Ahn YR, Oh HJ, Choi H, Choi I, Im E, Moon HR, Chung HY, Kim ND

We examined the anticancer effects of a novel sirtuin inhibitor, MHY2256, on HCT116 human colorectal cancer cells to investigate its underlying molecular mechanisms. MHY2256 significantly suppressed the activity of sirtuin...
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A Case of Superficial Basal Cell Carcinoma Not Correctly Diagnosed with Punch Biopsy but Diagnosed with Dermoscopy

Park TJ, Kim KE, Jeong JY, Ryu HJ, Son SW, Kim IH, Moon HR

  • KMID: 2504349
  • Korean J Dermatol.
  • 2020 Jul;58(6):419-422.
Basal cell carcinoma is a common cancer and has been reported to account for approximately 80% of non-melanoma skin cancers. Superficial basal cell carcinoma occurs mainly in the trunk or...
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A Retrospective Study of the Factors Associated with the Effect of Pulsed Dye Laser Treatment in Patients with Capillary Malformation

Park TJ, Moon HR, Son SW, Kim IH, Ryu HJ

  • KMID: 2502804
  • Korean J Dermatol.
  • 2020 Mar;58(3):185-190.
Background: Pulsed dye laser treatment is a proven effective treatment for capillary malformation. Previous studies have shown different responses to pulsed dye laser depending on the anatomical location of the...
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A New Histone Deacetylase Inhibitor, MHY4381, Induces Apoptosis via Generation of Reactive Oxygen Species in Human Prostate Cancer Cells

Richa S, Dey P, Park C, Yang J, Son JY, Park JH, Lee SH, Ahn MY, Kim IS, Moon HR, Kim HS

Histone deacetylase (HDAC) inhibitors represent a novel class of anticancer agents, which can be used to inhibit cell proliferation and induce apoptosis in several types of cancer cells. In this...
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An Extradigital Glomus Tumor on the Back, Mimicking a Keloid Scar

Ryu SI, Oh H, Ryu HJ, Son SW, Kim IH, Moon HR

  • KMID: 2454383
  • Korean J Dermatol.
  • 2019 Jul;57(6):349-350.
No abstract available.
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Metformin, an Activator of AMPK, Promotes the Growth of Hair Follicles via the AMPK/β-catenin Signaling Pathway

Moon HR, Park KY, Kang HJ, Lee WJ, Won CH, Chang SE, Lee MW, Choi JH, Park GH

  • KMID: 2449198
  • Korean J Dermatol.
  • 2019 May;57(4):175-181.
BACKGROUND: AMP-activated protein kinase (AMPK) is a serine/threonine protein kinase that plays a pivotal role in the balance of cellular energy metabolism. Recent studies have reported that AMPK has numerous...
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Childhood Granulomatous Periorificial Dermatitis of 2 Years Duration Treated by Tetracycline

Kim BY, Ryu SI, Park JH, Moon HR, Kim IH

  • KMID: 2436885
  • Korean J Dermatol.
  • 2018 Sep;56(8):508-510.
No abstract available.
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Atypical Proliferative Nodule with Melanocytic Intraepidermal Pagetoid Spreading Arising within a Congenital Melanocytic Nevus in a Pregnant Woman

Moon HR, Lee MH, Won CH, Chang SE, Lee MW, Choi JH, Moon KC

No abstract available.
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A New Histone Deacetylase Inhibitor, MHY219, Inhibits the Migration of Human Prostate Cancer Cells via HDAC1

De U, Kundu S, Patra N, Ahn MY, Ahn JH, Son JY, Yoon JH, Moon HR, Lee BM, Kim HS

Histone deacetylase (HDAC) inhibitors are considered novel agents for cancer chemotherapy. We previously investigated MHY219, a new HDAC inhibitor, and its potent anticancer activity in human prostate cancer cells. In...
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Treatment with the Pinhole Technique Using Erbium-Doped Yttrium Aluminium Garnet Laser for a Cafe au Lait Macule and Carbon Dioxide Laser for Facial Telangiectasia

Chung BY, Han SS, Moon HR, Lee MW, Chang SE

No abstract available.
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Recent Chemotherapy Reduces the Maximum-Standardized Uptake Value of 18F-Fluoro-Deoxyglucose Positron Emission Tomography in Colorectal Cancer

Lee M, Yeum TS, Kim JW, Oh S, Lee SA, Moon HR, Choi YH, Han YM, Choi JM, Jang DK

  • KMID: 1774558
  • Gut Liver.
  • 2014 May;8(3):254-264.
BACKGROUND/AIMS: The aim of this study was to evaluate the influence of recent chemotherapy on the patterns of the maximum-standardized uptake value (M-SUV) and sensitivity of 18F-fluoro-deoxyglucose positron emission tomography/computed...
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Grover's Disease in a Liver Transplant Patient

Moon HR, Lee JH, Rhee DY, Won CH, Chang SE, Lee MW, Choi JH, Moon KC

No abstract available.
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Dermatomyositis First Presenting as Panniculitis

Moon HR, Won KH, Won CH, Chang S, Lee MW, Choi JH, Moon KC

  • KMID: 1427492
  • Korean J Dermatol.
  • 2013 Apr;51(4):284-287.
Panniculitis is a rare cutaneous finding in dermatomyositis (DM), presenting as tender subcutaneous nodules. Because panniculitis may precede other symptoms of DM, and its complications, including pain, lipoatrophy and carcinosis,...
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A Case of Melanoma in situ in a Child Presented with Melanonychia

Lee SM, Moon HR, Jung JM, Won CH, Chang SE, Lee MW, Choi JH, Moon KC

  • KMID: 2247242
  • Korean J Dermatol.
  • 2013 Mar;51(3):211-214.
Melanonychia is a darkening of the nails and its importance is that it may indicate the presence of a subungual malignant melanoma. Because the incidence of malignant melanoma is quite...
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