- Can Calprotectin Show Subclinical Inflammation in Familial Mediterranean Fever Patients?
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Asan G, Derin ME, DoÄŸan HO, Bayram M, Åžahin M, Åžahin A
- KMID: 2471797
- J Korean Med Sci.
- 2020 Mar;35(10):e63.
- doi: 10.3346/jkms.2020.35.e63
BACKGROUND: Familial Mediterranean fever (FMF) is an autoinflammatory disease that has self-limiting inflammatory attacks during polyserositis. Hepcidin is a protein, and interleukin-6 stimulation increases hepcidin levels. Calprotectin (CLP) is a... -
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- Altered T cell and monocyte subsets in prolonged immune reconstitution inflammatory syndrome related with DRESS (drug reaction with eosinophilia and systemic symptoms)
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Kang SY, Kim J, Ham J, Cho SH, Kang HR, Kim HY
- KMID: 2469855
- Asia Pac Allergy.
- 2020 Jan;10(1):e2.
- doi: 10.5415/apallergy.2020.10.e2
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe cutaneous adverse reaction involving various internal organs. Flare-ups after recovery from the initial presentation of DRESS are caused... -
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- Telomere Biology in Mood Disorders: An Updated, Comprehensive Review of the Literature
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Muneer A, Minhas FA
- KMID: 2457398
- Clin Psychopharmacol Neurosci.
- 2019 Aug;17(3):343-363.
- doi: 10.9758/cpn.2019.17.3.343
Major psychiatric disorders are linked to early mortality and patients afflicted with these ailments demonstrate an increased risk of developing physical diseases that are characteristically seen in the elderly. Psychiatric... -
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- Intravenous Immunoglobulin Controls Th17 Cell-Mediated Osteoclastogenesis
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Kim KW, Kim HR, Kim BM, Won JY, Lee KA, Lee SH
- KMID: 2455937
- Immune Netw.
- 2019 Aug;19(4):e27.
- doi: 10.4110/in.2019.19.e27
The purpose of this study was to determine the regulatory role of intravenous Ig (IVIg) in Th17 cytokine–induced RANK ligand (RANKL) expression and osteoclast (OC) differentiation from OC precursors (pre-OC).... -
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- Risk Factors of Multiple Gastric Polyps according to the Histologic Classification: Prospective Observational Cohort Study
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Jeong CY, Kim N, Lee HS, Yoon H, Shin CM, Park YS, Kim JW, Lee DH
- KMID: 2453255
- Korean J Gastroenterol.
- 2019 Jul;74(1):17-29.
- doi: 10.4166/kjg.2019.74.1.17
BACKGROUND/AIMS: The aim of this study was to determine the risk factors of multiple gastric polyps according to the histological classification of gastric polyps. METHODS: Subjects with multiple gastric polyps (at... -
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- The Platelet-to-Lymphocyte Ratio as an Inflammatory Marker in Rheumatic Diseases
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Gasparyan , Ayvazyan L, Mukanova U, Yessirkepov M, Kitas GD
- KMID: 2438881
- Ann Lab Med.
- 2019 Jul;39(4):345-357.
- doi: 10.3343/alm.2019.39.4.345
The platelet-to-lymphocyte ratio (PLR) has emerged as an informative marker revealing shifts in platelet and lymphocyte counts due to acute inflammatory and prothrombotic states. PLR has been extensively examined in... -
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- Prominent Inflammatory Features of Monocytes/Macrophages in Acute Calcium Pyrophosphate Crystal Arthritis: a Comparison with Acute Gouty Arthritis
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Jeong JH, Jung JH, Lee JS, Oh JS, Kim YG, Lee CK, Yoo B, Hong S
- KMID: 2450206
- Immune Netw.
- 2019 Jun;19(3):e21.
- doi: 10.4110/in.2019.19.e21
Calcium pyrophosphate (CPP) crystals can present as acute inflammatory arthritis which is known as an acute CPP crystal arthritis. Although monocytes/macrophages have been shown to play a role in the... -
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- Respiratory Syncytial Virus Fusion Protein-encoding DNA Vaccine Is Less Effective in Conferring Protection against Inflammatory Disease than a Virus-like Particle Platform
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Kwon YM, Hwang HS, Lee YT, Kim KH, Lee Y, Kim MC, Lee YN, Quan FS, Moore ML, Kang SM
- KMID: 2450203
- Immune Netw.
- 2019 Jun;19(3):e18.
- doi: 10.4110/in.2019.19.e18
Formalin-inactivated respiratory syncytial virus (RSV) vaccination causes vaccine-enhanced disease (VED) after RSV infection. It is considered that vaccine platforms enabling endogenous synthesis of RSV immunogens would induce favorable immune responses... -
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- Galectin-4 Interaction with CD14 Triggers the Differentiation of Monocytes into Macrophage-like Cells via the MAPK Signaling Pathway
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Hong SH, Shin JS, Chung H, Park CG
- KMID: 2450202
- Immune Netw.
- 2019 Jun;19(3):e17.
- doi: 10.4110/in.2019.19.e17
Galectin-4 (Gal-4) is a β-galactoside-binding protein mostly expressed in the gastrointestinal tract of animals. Although intensive functional studies have been done for other galectin isoforms, the immunoregulatory function of Gal-4... -
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- Changes of Bax, Bcl-2, CCR-2, MCP-1, and TGF-β1 genes in the left ventricle of spontaneously hypertensive rat after losartan treatment
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Lee H, Kim KC, Hong YM
- KMID: 2447196
- Korean J Pediatr.
- 2019 Mar;62(3):95-101.
- doi: 10.3345/kjp.2018.06856
PURPOSE: Increased apoptosis was recently found in the hypertrophied left ventricle of spontaneously hypertensive rats (SHRs). Although the available evidence suggests that apoptosis can be induced in cardiac cells by... -
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- Comparison Between Signature Cytokines of Nasal Tissues in Subtypes of Chronic Rhinosinusitis
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Kim DK, Eun KM, Kim MK, Cho D, Han SA, Han SY, Seo Y, Lee DH, Cho SH, Kim DW
- KMID: 2431852
- Allergy Asthma Immunol Res.
- 2019 Mar;11(2):201-211.
- doi: 10.4168/aair.2019.11.2.201
PURPOSE: Endotype in chronic rhinosinusitis (CRS) has been established in the last decade. However, the exact immunologic profile of CRS still has controversy because it has a considerable immunologic heterogeneity.... -
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- Development of a Novel Flow Cytometry-Based System for White Blood Cell Differential Counts: 10-color LeukoDiff
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Park D, Chang J, Kahng J, Park H, Jo I, Kim Y, Han K
- KMID: 2425969
- Ann Lab Med.
- 2019 Mar;39(2):141-149.
- doi: 10.3343/alm.2019.39.2.141
BACKGROUND: Flow cytometry (FCM) is commonly used to identify many cell populations. We developed a white blood cell (WBC) differential counting system for detecting abnormal cells using FCM incorporating 10... -
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- Lymphocyte-monocyte ratio at day 14 of first cisplatin-doxorubicin chemotherapy is associated with treatment outcome of pediatric patients with localized osteosarcoma
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Lee JA, Oh HL, Kim DH, Lim JS
- KMID: 2440839
- Korean J Pediatr.
- 2019 Feb;62(2):62-67.
- doi: 10.3345/kjp.2018.06618
PURPOSE: We aimed to determine the prognostic significance of lymphocyte counts and the lymphocytemonocyte ratio (LMR) in pediatric patients with osteosarcoma. METHODS: We retrospectively reviewed the medical records of 27 pediatric... -
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- N-acetyl-l-cysteine controls osteoclastogenesis through regulating Th17 differentiation and RANKL in rheumatoid arthritis
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Kim HR, Kim KW, Kim BM, Lee KA, Lee SH
- KMID: 2452505
- Korean J Intern Med.
- 2019 Jan;34(1):210-219.
- doi: 10.3904/kjim.2016.329
BACKGROUND/AIMS: This study aimed to determine the regulatory role of N-acetyl-l-cysteine (NAC), an antioxidant, in interleukin 17 (IL-17)-induced osteoclast differentiation in rheumatoid arthritis (RA). METHODS: After RA synovial fibroblasts were stimulated... -
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- Sodium Chloride Aggravates Arthritis via Th17 Polarization
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Jung SM, Kim Y, Kim J, Jung H, Yi H, Rim YA, Park N, Kwok SK, Park SH, Ju JH
- KMID: 2428282
- Yonsei Med J.
- 2019 Jan;60(1):88-97.
- doi: 10.3349/ymj.2019.60.1.88
PURPOSE: Sodium chloride (NaCl) has been proposed as a driving factor in autoimmune diseases through the induction of pathogenic CD4+ T helper cells that produce interleukin-17 (Th17 cells). This study... -
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- L-plastin: Structure, Regulation, and Roles in Cancer Invasion and in Macrophages
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Kim HJ, Lee HH
- KMID: 2452070
- J Bacteriol Virol.
- 2018 Dec;48(4):175-180.
- doi: 10.4167/jbv.2018.48.4.175
The cytoskeleton consists of 3 filamentous components: intermediate filaments, microtubules, and actin filaments. Actin filaments continuously assemble and disassemble far out of equilibrium to adapt cells in response to external... -
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- Effect of Various Agents on Oral Bacterial Phagocytosis in THP-1 Cells
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Song Y, Lee HA, Na HS, Chung J
- KMID: 2437339
- Int J Oral Biol.
- 2018 Dec;43(4):217-222.
- doi: 10.11620/IJOB.2018.43.4.217
Phagocytosis is a fundamental process in which phagocytes capture and ingest foreign particles including pathogenic bacteria. Several oral pathogens have anti-phagocytic strategies, which allow them to escape from and survive... -
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- Inhibitory Effects of CD99-derived Peptide CD99CRIII3 on the Extravasation of Monocytes and Inflammatory Reactions in Contact Dermatitis Mouse Model
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Ju HM, Park KH
- KMID: 2430459
- Korean J Phys Anthropol.
- 2018 Dec;31(4):143-149.
- doi: 10.11637/kjpa.2018.31.4.143
Leucocyte extravasation has been known to play an important role in inflammatory reactions including contact dermatitis. Previous studies suggested that CD99 regulates β1 integrin activity and may be a novel... -
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- Complete Blood Count Reference Intervals and Patterns of Changes Across Pediatric, Adult, and Geriatric Ages in Korea
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Nah EH, Kim S, Cho S, Cho HI
- KMID: 2429114
- Ann Lab Med.
- 2018 Nov;38(6):503-511.
- doi: 10.3343/alm.2018.38.6.503
BACKGROUND: Sampling a healthy reference population to generate reference intervals (RIs) for complete blood count (CBC) parameters is not common for pediatric and geriatric ages. We established age- and sex-specific... -
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- Antiviral and Anti-Inflammatory Activities of Pochonin D, a Heat Shock Protein 90 Inhibitor, against Rhinovirus Infection
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Song JH, Shim A, Kim YJ, Ahn JH, Kwon BE, Pham TT, Lee J, Chang SY, Ko HJ
- KMID: 2427511
- Biomol Ther.
- 2018 Nov;26(6):576-583.
- doi: 10.4062/biomolther.2017.233
Human rhinoviruses (HRV) are one of the major causes of common cold in humans and are also associated with acute asthma and bronchial illness. Heat-shock protein 90 (Hsp90), a molecular... -
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