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Risk-Scoring System for Prediction of Non-Curative Endoscopic Submucosal Dissection Requiring Additional Gastrectomy in Patients with Early Gastric Cancer

Kim TS, Min BH, Kim KM, Yoo H, Kim K, Min YW, Lee H, Rhee PL, Kim JJ, Lee JH

Purpose: When patients with early gastric cancer (EGC) undergo non-curative endoscopic submucosal dissection requiring gastrectomy (NC-ESD-RG), additional medical resources and expenses are required for surgery. To reduce this burden, predictive...
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Long-term Outcomes of Undifferentiated-Type Early Gastric Cancer with Positive Horizontal Margins after Endoscopic Resection

Yang HJ, Lee WS, Lee BE, Ahn JY, Jang JY, Lim JH, Nam SY, Kim JH, Min BH, Joo MK, Park JM, Shin WG, Lee HL, Gweon TG, Park MI, Choi J, Tae CH, Kim YI, Choi IJ

Background/Aims: This study examined the long-term outcomes of undifferentiated-type early gastric cancer (UD EGC) with positive horizontal margins (HMs) after endoscopic resection (ER) and compared them between additional surgery and...
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Exosomes from IL-1b-Primed Mesenchymal Stem Cells Inhibited IL-1b- and TNF-a-Mediated Inflammatory Responses in Osteoarthritic SW982 Cells

Kim M, Shin DI, Choi BH, Min BH

BACKGROUND: Exosomes from mesenchymal stem cells (MSCs) show anti-inflammatory effect on osteoarthritis (OA); however, their biological effect and mechanism are not yet clearly understood. This study investigated the anti-inflammatory effect and...
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Papillary Adenocarcinoma

Kim TS, Min BH

Gastric papillary adenocarcinoma is one of the histological variants of gastric cancer that shows more aggressive clinicopathological behavior compared to tubular adenocarcinoma. Previous studies have reported higher lymphovascular and submucosal...
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Corneal Repair with Adhesive Cell Sheets of Fetal Cartilage-Derived Stem Cells

Park IS, Kim BK, Truong MD, Yang HS, Park SH, Park HS, Choi BH, Won BH, Min BH

BACKGROUND: Corneal scarring or disease may lead to severe corneal opacification and consequently, severe loss of vision due to the complete loss of corneal epithelial cells. We studied the use...
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Clinical Practice Guideline for the Management of Antithrombotic Agents in Patients Undergoing Gastrointestinal Endoscopy

Lim H, Gong EJ, Min BH, Kang SJ, Shin CM, Byeon JS, Choi M, Park CG, Cho JY, Lee ST, Kim HG, Chun HJ

Antithrombotic agents, including antiplatelet agents and anticoagulants, are increasingly used in South Korea. The management of patients using antithrombotic agents and requiring gastrointestinal endoscopy is an important clinical challenge. Although...
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Clinical Practice Guideline for the Management of Antithrombotic Agents in Patients Undergoing Gastrointestinal Endoscopy

Lim H, Gong EJ, Min BH, Kang SJ, Shin CM, Byeon JS, Choi M, Park CG, Cho JY, Lee ST, Kim HG, Chun HJ

Antithrombotic agents, including antiplatelet agents and anticoagulants, are increasingly used in South Korea. The management of patients using antithrombotic agents and requiring gastrointestinal endoscopy is an important clinical challenge. Although...
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Inhibitory Effect of Topical Cartilage Acellular Matrix Suspension Treatment on Neovascularization in a Rabbit Corneal Model

Yun HW, Choi BH, Park DY, Jin LH, Min BH

BACKGROUND: The extracellular matrix (ECM) of articular cartilage has an inhibitory effect on vascularization, yet clinical utilization has been technically challenging. In this study, we aimed to fabricate a biologically...
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Endoscopic Prediction for Acid Reflux in Patients without Hiatus Hernia

Kim JY, Shin IS, Min YW, Kim K, Lee H, Min BH, Lee JH, Kim JJ, Rhee PL

Background/Aims: A diagnosis of gastroesophageal reflux disease is challenging in patients who have reflux symptoms but do not respond to proton pump inhibitors nor have reflux esophagitis and hiatal hernia...
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In Vivo Bioreactor Using Cellulose Membrane Benefit Engineering Cartilage by Improving the Chondrogenesis and Modulating the Immune Response

Li XG, Park IS, Choi BH, Kim UJ, Min BH

BACKGROUND: To regenerate tissue-engineered cartilage as a source of material for the restoration of cartilage defects, we used a human fetal cartilage progenitor cell pellet to improve chondrogenesis and modulation...
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Impact of Sarcopenia on the Risk of Erosive Esophagitis

Heo CM, Kim TJ, Lee H, Pyo JH, Min YW, Min BH, Lee JH, Son HJ, Baek SY, Kim K, Ryu S, Rhee PL, Kim JJ

BACKGROUND/AIMS: An association between obesity and erosive esophagitis has been reported, but the effects of sarcopenia and obesity on erosive esophagitis are unknown. This study examined the relationship between obesity,...
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Obstetrical Vacuum Extraction for Ping-Pong Fracture of Newborn

Min BH, Cho YJ, Yoon SH, Shim GH, Kim M, Ko JK, Lee C, Cho YK, Choi H

Depressed skull fracture is an inward buckling of the skull bones. It is referred to as a ping-pong fracture in neonates. It is usually not associated with significant neurological injury....
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Combined Multichannel Intraluminal Impedance and High-resolution Manometry Improves Detection of Clinically Relevant Esophagogastric Junction Outflow Obstruction

Song BG, Min YW, Lee H, Min BH, Lee JH, Rhee PL, Kim JJ

  • KMID: 2433500
  • J Neurogastroenterol Motil.
  • 2019 Jan;25(1):75-81.
  • doi: 10.5056/jnm18148
BACKGROUND/AIMS: Esophagogastric junction outflow obstruction (EGJOO) is a diagnostically heterogeneous group with variable clinical relevance. We studied whether evaluation of bolus transit by multichannel intraluminal impedance (MII) is useful for...
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Characterization of Human Fetal Cartilage Progenitor Cells During Long-Term Expansion in a Xeno-Free Medium

Kim HR, Kim J, Park SR, Min BH, Choi BH

BACKGROUND: Stem cell therapy requires a serum-free and/or chemically-defined medium for commercialization, but it is difficult to find one that supports long-term expansion of cells without compromising their stemness, particularly...
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Electrostatically Interactive Injectable Hydrogels for Drug Delivery

Seo JY, Lee B, Kang TW, Noh JH, Kim MJ, Ji YB, Ju HJ, Min BH, Kim MS

BACKGROUND: Several injectable hydrogels have been developed extensively for a broad range of biomedical applications. Injectable hydrogels forming in situ through the change in external stimuli have the distinct properties...
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Three-Dimensional Spheroid Culture Increases Exosome Secretion from Mesenchymal Stem Cells

Kim M, Yun HW, Park DY, Choi BH, Min BH

BACKGROUND: Mass production of exosomes is a prerequisite for their commercial utilization. This study investigated whether three-dimensional (3D) spheroid culture of mesenchymal stem cells (MSCs) could improve the production efficiency...
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Lack of Association between Helicobacter pylori Infection and Various Markers of Systemic Inflammation in Asymptomatic Adults

Kim TJ, Pyo JH, Lee H, Baek SY, Ahn SH, Min YW, Min BH, Lee JH, Son HJ, Rhee PL, Kim JJ

BACKGROUND/AIMS: Helicobacter pylori (H. pylori) infection has been known to cause various extra-gastric diseases, which may be mediated by an increase in systemic inflammation. Thus, we examined the association between...
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Nondestructive Assessment of Glycosaminoglycans in Engineered Cartilages Using Hexabrix-Enhanced Micro-Computed Tomography

Jin LH, Choi BH, Kim YJ, Oh HJ, Kim BJ, Yin XY, Min BH

It is very useful to evaluate the content and 3D distribution of extracellular matrix non-destructively in tissue engineering. This study evaluated the feasibility of using micro-computed tomography (µCT) with Hexabrix...
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Mechanically Reinforced Extracellular Matrix Scaffold for Application of Cartilage Tissue Engineering

Oh HJ, Kim SH, Cho JH, Park SH, Min BH

Scaffolds with cartilage-like environment and suitable physical properties are critical for tissue-engineered cartilage repair. In this study, decellularized porcine cartilage-derived extracellular matrix (ECM) was utilized to fabricate ECM scaffolds. Mechanically...
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Outcomes of Endoscopic Submucosal Dissection for Early Gastric Cancer with Undifferentiated-Type Histology: A Clinical Simulation Using a Non-Selected Surgical Cohort

Kwak DS, Min YW, Lee JH, Kang SH, Jang SH, Lee H, Min BH, Kim JJ, Kim KM, Sohn TS, Kim S

BACKGROUND/AIMS: Outcomes of endoscopic submucosal dissection (ESD) for undifferentiated-type early gastric cancer (EGC) need to be further evaluated. We aimed to simulate the outcomes of ESD for undifferentiated-type EGC from...
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