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Cognition enhancing effect of panax ginseng in Korean volunteers with mild cognitive impairment: a randomized, double-blind, placebo-controlled clinical trial

Park KC, Jin H, Zheng R, Kim S, Lee SE, Kim BH, Yim SV

This study aimed to investigate the cognition-enhancing effect of Panax ginseng. A randomized, double-blind, placebo-controlled clinical trial was conducted to address the cognition-enhancing effects of Panax ginseng. A total of...
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The Effect of Daily Low Dose Tadalafil on Cerebral Perfusion and Cognition in Patients with Erectile Dysfunction and Mild Cognitive Impairment

Choi JB, Cho KJ, Kim JC, Kim CH, Chung YA, Jeong HS, Shim YS, Koh JS

OBJECTIVE: The aims of this study were to investigate the effects of daily low-dose tadalafil on cognitive function and to examine whether there was a change in cerebral blood flow...
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Clinical Characteristics of Non-Amnestic Mild Cognitive Impairment: A Single-Center Experience

Oh E, Shin CW, Kim BJ, Hwang KJ, Heo SH, Ahn TB, Chang DI, Yoon SS, Park KC, Lee JS

BACKGROUND: To evaluate the clinical characteristics of patients with non-amnestic mild cognitive impairment (naMCI) in a memory disorder clinic at a single center. METHODS: A retrospective study was conducted involving 312...
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Validation Study of the Chinese Version of Addenbrooke's Cognitive Examination III for Diagnosing Mild Cognitive Impairment and Mild Dementia

Li X, Yang L, Yin J, Yu N, Ye F

BACKGROUND AND PURPOSE: There are only a few cognitive screening tests for the Chinese-speaking population, and so this study aimed to validate the Chinese version of Addenbrooke's Cognitive Examination III...
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Effects of Subjective Memory Complaints, Depression and Executive Function on Activities of Daily Living in Individuals with Mild Cognitive Impairment

Jung MS, Oh EY, Chung EY

PURPOSE: This study aimed to examine the effects of subjective memory complaints, depression and cognitive function on performance of activities of daily living (ADL) in individuals with mild cognitive impairment...
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Association between Thyroid-Related Hormones and Cognitive Function in Patients with Alzheimer's Disease and Mild Cognitive Impairment

Park DY, Kim H, Lee KJ

OBJECTIVES: The association between thyroid-related hormones and cognitive function has been controversial. The purpose of this study is to compare the levels of thyroid-related hormones in patients with Alzheimer's disease...
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Development and Evaluation of a Community based Multifaceted Cognitive Training Program for the Elderly with Mild Cognitive Impairment

Park Y, Oh H

PURPOSE: The purpose of this study is to develop and evaluate the effects of a multifaceted cognitive training program on cognitive function, depression, and instrumental activities of daily living (IADL)...
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Clustering and Switching Patterns in Semantic Fluency and Their Relationship to Working Memory in Mild Cognitive Impairment

Oh SJ, Sung JE, Choi SJ, Jeong JH

BACKGROUND AND PURPOSE: Semantic verbal fluency test is a neuropsychological assessment that can sensitively detect neuropathological changes. Considering its multifactorial features tapping various cognitive domains such as semantic memory, executive...
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Central Auditory Processing Tests as Diagnostic Tools for the Early Identification of Elderly Individuals with Mild Cognitive Impairment

Jalaei B, Valadbeigi A, Panahi R, Nahrani MH, Arefi HN, Zia M, Ranjbar N

BACKGROUND AND OBJECTIVES: Mild cognitive impairment (MCI) is a disorder that usually occurs in the elderly, leading to dementia in some progressive cases. The purpose of this study is to...
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A Comparison of Memory Beliefs, Cognitive Activity, and Depression Among Healthy Older Adults, Amnestic Mild Cognitive Impairment, and Patient with Alzheimer's Disease

Park J, Im JJ, Song IU, Kang Y

BACKGROUND: Amnestic mild cognitive impairment (aMCI) is highly likely to progress to dementia of the Alzheimer type (DAT). One of the most frequently reported symptoms in aMCI and DAT patients...
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The Association of Plasma Inflammatory Cytokines with Dementia and Mild Cognitive Impairment

Son KH, Seong SJ, Lee WJ, Hwang JY, Han JH, Jeon YJ, Han CH

OBJECTIVES: The aim of this study was to investigate the association of plasma levels of inflammatory cytokines with dementia and mild cognitive impairment. METHODS: We compared serum levels of tumor necrosis...
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Association between Cognitive function, Behavioral and Psychological Symptoms of Dementia and Temporal Lobe Atrophy in Patients with Alzheimer's Disease and Mild Cognitive Impairment

Jeong JY, Lee KJ, Kim H

OBJECTIVES: The aim of this study was to compare severity, neurocognitive functions, and behavioral and psychological symptoms of dementia (BPSD) according to the degree of temporal lobe atrophy (MTA) in...
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The Effect of Clinical Characteristics and Subtypes on Amyloid Positivity in Patients with Amnestic Mild Cognitive Impairment

Kim JY, Lim JH, Jeong YJ, Kang DY, Park KW

BACKGROUND AND PURPOSE: Mild cognitive impairment (MCI) is a prodromal stage of dementia. Amyloid deposits in positron-emission tomography (PET) imaging of MCI patients imply a higher risk for advancing to...
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Group-Based Cognitive Intervention for People Affected with Leprosy and Mild Cognitive Impairment: A Clinic Based Study

Lee MW

BACKGROUND: Mild cognitive impairment represents a cognitive state between the subject memory impairment and early dementia. Proper cognitive interventions at this period can delay its development into dementia. However, it...
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Electrophysiological Characteristics of Mild Cognitive Impairment Patients during Semantic Memory Process

Lee K, Han JW, Lee S, Kim GE, Na E, Suh SW, Kim KW

OBJECTIVES: Mild cognitive impairment (MCI) patients show decreased semantic memory-processing ability including that for naming objects. We examined event-related potentials (ERPs) associated with the semantic processing of MCI patients and...
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Impact of Repetitive Transcranial Magnetic Stimulation with Computerized Cognitive Enhancement Training on Change in Cognitive Function of Mild Cognitive Impairment Patients : Existing, Sham Treatment Controlled, Pilot Study

Lee SE, Moon HS, Chung ST, Lee CU, Kang DW

OBJECTIVE: This study aimed to investigate the effects of repetitive transcranial magnetic stimulation (rTMS) and computerized cognitive enhancement training combined treatment on cognitive function in mild cognitive impairment (MCI) patients,...
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Plasma Fibrinogen and C-Reactive Protein Levels in Alzheimer's Disease and Mild Cognitive Impairment

Jang WJ, Kim H, Lee KJ

OBJECTIVE: The aim of this study was to measure and compare the levels of fibrinogen and C-reactive protein (CRP) in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI)...
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Distinct Neural Correlates of Executive Function by Amyloid Positivity and Associations with Clinical Progression in Mild Cognitive Impairment

Yoon HJ, Kim SG, Kim SH, Choo IH, Park SH, Seo EH, For the Alzheimer's Disease Neuroimaging Initiative

PURPOSE: This study aimed to identify the neural basis of executive function (EF) in amnestic mild cognitive impairment (aMCI) according to beta-amyloid (Aβ) positivity. Furthermore, we explored if the identified...
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Qualitative Comparison of Semantic Memory Impairment in Patients with Amnestic Mild Cognitive Impairment Based on β-Amyloid Status

Kim JE, Park SH, Hong YJ, Hwang J, Han NE, Lee SM, Roh JH, Kim JS, Lee JH

BACKGROUND AND PURPOSE: Semantic memory remains more stable than episodic memory across the lifespan, which makes it potentially useful as a marker for distinguishing pathological aging from normal senescence. To...
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Prospective Memory Loss and Related White Matter Changes in Patients with Amnestic Mild Cognitive Impairment

Yoon B, Ryu SY, Yoon SJ

BACKGROUND AND PURPOSE: Prospective memory (PM) has a known relationship with frontal function, and PM decline has been observed in amnestic mild cognitive impairment (aMCI). Cerebral small vessel disease, as...
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