- Alzheimer's Disease Diagnosis Using Misfolding Proteins in Blood
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Lee H, Ugay D, Hong S, Kim Y
- KMID: 2471931
- Dement Neurocogn Disord.
- 2020 Mar;19(1):1-18.
- doi: 10.12779/dnd.2020.19.1.1
Alzheimer's disease (AD) is pathologically characterized by a long progressive phase of neuronal changes, including accumulation of extracellular amyloid-β (Aβ) and intracellular neurofibrillary tangles, before the onset of observable symptoms.... -
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- Carbon-Fiber Based Microelectrode Array Embedded with a Biodegradable Silk Support for In Vivo Neural Recording
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Lee Y, Kong C, Chang JW, Jun SB
- KMID: 2432104
- J Korean Med Sci.
- 2019 Jan;34(4):e24.
- doi: 10.3346/jkms.2019.34.e24
BACKGROUND: Recently, carbon fibers have been utilized to develop a depth-type microelectrode array for chronic neural recording. Since the diameter of carbon fibers is smaller than the conventional electrodes made... -
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- Characterization of Tetrodes Coated with Au Nanoparticles (AuNPs) and PEDOT and Their Application to Thalamic Neural Signal Detection in vivo
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Lee D, Moon HC, Tran BT, Kwon DH, Kim YH, Jung SD, Joo JH, Park YS
- KMID: 2430114
- Exp Neurobiol.
- 2018 Dec;27(6):593-604.
- doi: 10.5607/en.2018.27.6.593
Tetrodes, consisting of four twisted micro-wires can simultaneously record the number of neurons in the brain. To improve the quality of neuronal activity detection, the tetrode tips should be modified... -
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- Electrical Activity of the Bladder Is Attenuated by Intravesical Inhibition of P2X2/3 Receptors During Micturition in Female Rats
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Salazar BH, Hoffman KA, Zhang C, Kavanagh A, Zhang Y, Boone TB, Munoz A
- KMID: 2400893
- Int Neurourol J.
- 2017 Dec;21(4):259-269.
- doi: 10.5213/inj.1734998.499
PURPOSE: To simultaneously monitor electrical discharges in various bladder regions and the external urethral sphincter (EUS) during voiding contractions, and to assess the functional role of myogenic modulation of the... -
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- Electrophysiological and Mechanical Characteristics in Human Ileal Motility: Recordings of Slow Waves Conductions and Contractions, In vitro
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Ryoo SB, Oh HK, Moon SH, Choe EK, Yu SA, Park SH, Park KJ
- KMID: 2070793
- Korean J Physiol Pharmacol.
- 2015 Nov;19(6):533-542.
- doi: 10.4196/kjpp.2015.19.6.533
Little human tissue data are available for slow waves and migrating motor complexes, which are the main components of small bowel motility. We investigated the electrophysiological and mechanical characteristics of... -
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- Emerging Neural Stimulation Technologies for Bladder Dysfunctions
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Lee JW, Kim D, Yoo S, Lee H, Lee GH, Nam Y
- KMID: 2380820
- Int Neurourol J.
- 2015 Mar;19(1):3-11.
- doi: 10.5213/inj.2015.19.1.3
In the neural engineering field, physiological dysfunctions are approached by identifying the target nerves and providing artificial stimulation to restore the function. Neural stimulation and recording technologies play a central... -
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- The Effects of Eupatilin (Stillen(R)) on Motility of Human Lower Gastrointestinal Tracts
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Ryoo SB, Oh HK, Yu SA, Moon SH, Choe EK, Oh TY, Park KJ
- KMID: 2285536
- Korean J Physiol Pharmacol.
- 2014 Oct;18(5):383-390.
- doi: 10.4196/kjpp.2014.18.5.383
Gastrointestinal motility consists of phasic slow-wave contractions and the migrating motor complex (MMC). Eupatilin (Stillen(R)) has been widely used to treat gastritis and peptic ulcers, and various cytokines and neuropeptides... -
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- Influence of Propofol and Fentanyl on Deep Brain Stimulation of the Subthalamic Nucleus
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Kim W, Song IH, Lim YH, Kim MR, Kim YE, Hwang JH, Kim IK, Song SW, Kim JW, Lee WW, Kim HJ, Kim C, Kim HC, Kim IY, Park HP, Kim DG, Jeon BS, Paek SH
- KMID: 1794608
- J Korean Med Sci.
- 2014 Sep;29(9):1278-1286.
- doi: 10.3346/jkms.2014.29.9.1278
We investigated the effect of propofol and fentanyl on microelectrode recording (MER) and its clinical applicability during subthalamic nucleus (STN) deep brain stimulation (DBS) surgery. We analyzed 8 patients with... -
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- Deep Brain Stimulation of the Globus Pallidus in a 7-Year-Old Girl with DYT1 Generalized Dystonia
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Jin ST, Lee MK, Ghang JY, Jeon SM
- KMID: 2339949
- J Korean Neurosurg Soc.
- 2012 Sep;52(3):261-263.
The experience of pediatric deep brain stimulation (DBS) of the globus pallidus internus (GPi) in the treatment of early-onset DYT1 generalized dystonia is still limited. Here, we report the surgical... -
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- Methionine Enhances the Contractile Activity of Human Colon Circular Smooth Muscle In Vitro
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Choe EK, Moon JS, Park KJ
- KMID: 2157923
- J Korean Med Sci.
- 2012 Jul;27(7):777-783.
- doi: 10.3346/jkms.2012.27.7.777
Effective drug to manage constipation has been unsatisfactory. We sought to determine whether methionine has effect on the human colon. Human colon tissues were obtained from the specimens of colon... -
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- Spontaneous Oscillatory Rhythm in Retinal Activities of Two Retinal Degeneration (rd1 and rd10) Mice
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Goo YS, Ahn KN, Song YJ, Ahn SH, Han SK, Ryu SB, Kim KH
- KMID: 2285429
- Korean J Physiol Pharmacol.
- 2011 Dec;15(6):415-422.
- doi: 10.4196/kjpp.2011.15.6.415
Previously, we reported that besides retinal ganglion cell (RGC) spike, there is ~ 10 Hz oscillatory rhythmic activity in local field potential (LFP) in retinal degeneration model, rd1 mice. The... -
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- Measurement of Bladder Volume Using an Implantable Volume Sensor in Rats
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Lee DS, Kim SJ, Sohn DW, Yoo JM, Choi BK, Lee MK, Lee SJ, Kim SW
- KMID: 2298752
- Korean J Androl.
- 2010 Dec;28(3):169-174.
PURPOSE: Real-time monitoring of urinary bladder volume can not only provide information on urinary bladder function more precisely in laboratories and in the setting of intravesical pressure monitoring, but can... -
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- Outcome of Pallidal Deep Brain Stimulation in Meige Syndrome
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Ghang JY, Lee MK, Jun SM, Ghang CG
- KMID: 2138390
- J Korean Neurosurg Soc.
- 2010 Aug;48(2):134-138.
- doi: 10.3340/jkns.2010.48.2.134
OBJECTIVE: Meige syndrome is the combination of blepharospasm and oromandibular dystonia. We assessed the surgical results of bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) in patients with medically... -
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- Electrophysiological Characteristics of Human Colon Circular Muscle
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Choe EK, Ryoo SB, Moon SH, Moon JS, Park KJ
- KMID: 2198805
- J Korean Soc Coloproctol.
- 2010 Apr;26(2):105-110.
- doi: 10.3393/jksc.2010.26.2.105
PURPOSE: Interstitial cells of Cajal (ICC) play a core function in colonic motility as a pacemaker by regulating the slow wave. We intended to investigate the electrophysiological characteristics of the... -
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- Pallidal Deep Brain Stimulation in Primary Cervical Dystonia with Phasic Type : Clinical Outcome and Postoperative Course
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Jeong SG, Lee MK, Kang JY, Jun SM, Lee WH, Ghang CG
- KMID: 2066691
- J Korean Neurosurg Soc.
- 2009 Oct;46(4):346-350.
- doi: 10.3340/jkns.2009.46.4.346
OBJECTIVE: The purpose of this study was to analyze in detail the relationship between outcome and time course of effect in medically refractory primary cervical dystonia (CD) with phasic type... -
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- Comparison of Retinal Waveform between Normal and rd/rd Mouse
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Ye JH, Seo JH, Goo YS
- KMID: 1482431
- Korean J Med Phys.
- 2008 Sep;19(3):157-163.
Retinal prosthesis is regarded as the most feasible method for the blind caused by retinal diseases such as retinitis pigmentosa or age-related macular degeneration. One of the prerequisites for the... -
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- STN DBS of Advanced Parkinson's Disease Experienced in a Specialized Monitoring Unit with a Prospective Protocol
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Lee JY, Han JH, Kim HJ, Jeon BS, Kim DG, Paek SH
- KMID: 2189477
- J Korean Neurosurg Soc.
- 2008 Jul;44(1):26-35.
- doi: 10.3340/jkns.2008.44.1.26
OBJECTIVE: In the evaluation of patients with Parkinson's disease (PD), most neurologists only see their patients during a limited period of their fluctuating 24-hour-a-day lives. This study aimed to assess... -
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- Electrical Stimulation Parameters in Normal andDegenerate Rabbit Retina
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Jin GH, Goo YS
- KMID: 1482454
- Korean J Med Phys.
- 2008 Mar;19(1):73-79.
Retinal prosthesis is regarded as the most feasible method for the blind caused by retinal diseases such as retinitis pigmentosa (RP) or age related macular degeneration (AMD). Recently Korean consortium... -
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- The Effect of Low-Level Laser Irradiation on Activities of Dorsal Horn Neurons in Rats with Experimental Muscle Pain
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Sohn MK, Yoon YS, Lee SH, Kang SK, Kim BO, Sohn JH
- KMID: 2324267
- J Korean Acad Rehabil Med.
- 2005 Oct;29(5):513-520.
OBJECTIVE: This study was performed to investigate the effects of low-level laser irradiation on the dorsal horn cell activities in the rats with experimental muscle pain. METHOD: Experimental muscle pain... -
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- Waveform Sorting of Rabbit Retinal Ganglion Cell Activity Recorded with Multielectrode Array
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Jin GH, Lee TS, Goo YS
- KMID: 2080301
- Korean J Med Phys.
- 2005 Sep;16(3):148-154.
Since the output of retina for visual stimulus is carried by neurons of very diverse functional properties, it is not adequate to use conventional single electrode for recording the retinal... -
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