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Alterations in lung and gut microbiota reduce diversity in patients with nontuberculous mycobacterial pulmonary disease

Choi JY, Shim B, Park Y, Kang YA

Background/Aims: Although the incidence of nontuberculous mycobacteria pulmonary disease (NTM-PD), a chronic infectious disease, is increasing, lung and gut microbiota dysbiosis in NTM patients has rarely been studied and was...
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Distinct Effects of Non-absorbed Agents Rifaximin and Berberine on the Microbiota-Gut-Brain Axis in Dysbiosis-induced Visceral Hypersensitivity in Rats

Zhang J, Zhang C, Zhang T, Zhang L, Duan L

  • KMID: 2546976
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):520-531.
  • doi: 10.5056/jnm22182
Background/Aims Irritable bowel syndrome (IBS) is accepted as a disorder of gut-brain interactions. Berberine and rifaximin are non-absorbed antibiotics and have been confirmed effective for IBS treatment, but there is still...
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The Effect of Curcumin on the Gut-Brain Axis: Therapeutic Implications

Enayati A, Soghi A, Butler AE, Rizzo M, Sahebkar A

  • KMID: 2546964
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):409-418.
  • doi: 10.5056/jnm23065
The gut-brain axis describes the bidirectional communication between the gut, the enteric nervous system, and the central nervous system. The gut-brain axis has attracted increasing attention owing to its regulatory...
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Human Immunodeficiency Virus Infection and Gut Microbiota: A Review on Gut Microbiome Associated with Immune Activation and Metabolic Diseases

Joo EJ

This review provides the complex interaction between human immunodeficiency virus (HIV) infection and gut microbiota. HIV infection exerts chronic effects by impairing the immune system, closely linked with alterations in...
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Probiotic supplementation has sexdependent effects on immune responses in association with the gut microbiota in community-dwelling older adults: a randomized, double-blind, placebocontrolled, multicenter trial

Kim CS, Jung MH, Choi EY, Shin DM

BACKGROUND/OBJECTIVES: Probiotics have been suggested as potent modulators of agerelated disorders in immunological functions, yet little is known about sex-dependent effects of probiotic supplements. Therefore, we aimed to investigate sex-dependent...
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Gut microbiota and nonalcoholic fatty liver disease

Kim B, Kim B

The gut microbiota has been reported to exert a significant influence on various physiological responses of hosts. Extensive evidence has recently emerged linking metabolic and cardiovascular disorders to the gut...
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Ischemic colitis complicated by Clostridioides difficile infection treated with fecal microbiota transplantation

Kang SH, Gweon TG, Hwang H, Baeg MK

Ischemic colitis is an inflammatory condition of the colon that results from insufficient blood supply commonly caused by enterocolitis, vessel occlusion, or shock. In contrast, pseudomembranous colitis is a clinical...
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Impact of Diet on Colorectal Cancer Progression and Prevention: From Nutrients to Neoplasms

Kim SH, Park DH, Lim YJ

Colorectal cancer (CRC), one of the most common cancers worldwide, continues to increase in incidence and mortality rates. This trend is closely linked to changes in dietary habits, which are...
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Gut Microbiome and Colorectal Cancer

Gweon TG

Colorectal cancer (CRC) is one of the most common cancers in Korea. A majority of CRCs are caused by progressive genomic alterations referred to as the adenoma-carcinoma sequence. The factors...
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A ketogenic diet reduces body weight gain and alters insulin sensitivity and gut microbiota in a mouse model of diet-induced obesity

Heo S, Yang SJ

Purpose: Ketogenic diets (KDs) have anti-obesity effects that may be related to glucose control and the gut microbiota. This paper hypothesizes that KD reduces body weight and changes the insulin...
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6-Shogaol, an Active Ingredient of Ginger, Improves Intestinal and Brain Abnormalities in Proteus Mirabilis-Induced Parkinson’s Disease Mouse Model

Huh E, Choi JG, Choi Y, Ju IG, Noh D, Shin Dy, Kim DH, Park HJ, Oh MS

Parkinson’s disease (PD) which has various pathological mechanisms, recently, it is attracting attention to the mechanism via microbiome-gut-brain axis. 6-Shogaol, a representative compound of ginger, have been known for improving...
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Gut microbiota affects brain development and behavior

Kim GH, Shim JO

The gut covers a large surface area of the body and faces various external factors. The brain works in concert with commensal microbes in the gut to efficiently process the...
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Research progress and treatment of radiation enteritis and gut microbiota

Ren H, Wu Q, Sun Z, Fang M, Liu J, Luo J

Radiation enteritis is a kind of intestinal radiation injury in patients with pelvic and retroperitoneal malignancies after radiotherapy, and its occurrence and development process are very complicated. At present, studies...
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Revolutionizing gut health: exploring the role of gut microbiota and the potential of microbiome-based therapies in lower gastrointestinal diseases

Park YE, Kim JH

The gut microbiota comprises a collection of microorganisms residing in the human digestive system, including bacteria, viruses, and fungi. These microbes have critical roles in food breakdown, immune system regulation,...
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Cobalt-induced neuro-behavioural alterations are accompanied by profound Purkinje cell and gut-associated responses in rats

Akinrinde A, Adigun K, Mustapha O

Metal ions including cobalt (Co) ions reportedly exhibit neurotoxic and antimicrobial properties. We hypothesized that oral exposure to Co may have implications for gut-dysbiosis with possible alterations of microbiota-gut-brain signaling...
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Effect of preoperative immunonutrition on fecal microbiota in colon cancer patients: a secondary analysis of a randomized controlled trial

Lee SY, Lee J, Park Hm, Kim CH, Kim HR

BACKGROUND/OBJECTIVES: This study aimed to evaluate the effect of preoperative immunonutrition on the composition of fecal microbiota following a colon cancer surgery. MATERIALS/METHODS: This study was a secondary analysis of a...
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Cellular and Molecular Mechanisms of Intestinal Fibrosis

Wu X, Lin X, Tan J, Liu Z, He J, Hu F, Wang, Y, Chen M, Liu F, Mao R

Intestinal fibrosis associated stricture is a common complication of inflammatory bowel disease usually requiring endoscopic or surgical intervention. Effective anti-fibrotic agents aiming to control or reverse intestinal fibrosis are still...
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Differences in Urine Microbiome of Acute Cystitis and Chronic Recurrent Cystitis in Women

Kim WB

The diagnosis of urinary tract infection (UTI) relies on urine culture tests to identify aerobic or anaerobic urinary tract pathogens. This method has limitations in identifying anaerobic bacteria, and there...
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Total Transit Time and Probiotic Persistence in Healthy Adults: A Pilot Study

Tremblay A, Auger J, Alyousif Z, Caballero Calero SE, Mathieu O, Rivero-Mendoza D, Elmaoui A, Dahl W, Tompkins TA

  • KMID: 2541574
  • J Neurogastroenterol Motil.
  • 2023 Apr;29(2):218-228.
  • doi: 10.5056/jnm22031
Background/Aims Motility, stool characteristics, and microbiota composition are expected to modulate probiotics’ passage through the gut but their effects on persistence after intake cessation remain uncharacterized. This pilot, open-label study aims...
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Brain–Gut–Microbiota Axis

Lee A, Lee JY, Jung SW, Shin SY, Ryu HS, Jang SH, Kwon JG, Kim YS

Patients frequently report that stress causes or exacerbates gastrointestinal (GI) symptoms, indicating a functional relationship between the brain and the GI tract. The brain and GI tract are closely related...
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