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Role of ascorbic acid in dapsone induced methemoglobinemia

Sahu KK, Mishra AK

No abstract available.
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Therapeutic effect of ascorbic acid on dapsone-induced methemoglobinemia in rats

Kang C, Kim DH, Kim T, Lee SH, Jeong JH, Lee SB, Kim JH, Jung MH, Lee KW, Park IS

OBJECTIVE: Dapsone (diaminodiphenyl sulfone, DDS) is currently used to treat leprosy, malaria, dermatitis herpetiformis, and other diseases. It is also used to treat pneumocystis pneumonia and Toxoplasma gondii infection in...
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Benzocaine, Methemoglobinemia and Methylene Blue

Lee J, Kim J

The aim of this review is to introduce about the issue of benzocaine and methemoglobinemia. Through blocking the pain during dental treatment, fear and anxiety of patients will be reduced....
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A Case of a Herbicide Poisoning Induced Methemoglobinemia Patient Treated with High-dose Vitamin C

Sun KH, Kim JK, Ryu CY, Kim SJ, Jo HK, Yoo TH, Park YJ, Kim SP

Methemoglobinemia is a condition in which the iron portion of hemoglobin, which binds to oxygen, is oxidized to produce methemoglobin, which increases blood concentration. There are many causes of methemoglobinemia,...
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A Case of Methemoglobinemia Caused by Primaquine

Lee JY, Kim SH, An S, Oh HS, Yi SY, Lee HH, Han DJ

Primaquine is often administered for the hypnozoite stage of Plasmodium vivax and Plasmodium ovale. Primaquine (with clindamycin) is also an alternative drug for treatment of pneumocystis pneumonia when trimethoprim/sulfamethoxazole cannot...
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Methemoglobinemia Caused by an Inert Ingredient after Intentional Ingestion of Pesticide

Jeong RB, Sohn CH, Seo DW, Kim WY, Ryoo SM, Oh BJ, Lim KS

We report two cases of toxic methemoglobinemia caused by an inert ingredient in pesticide product after intentional ingestion of pesticide. First, 51-year-old male visited to the emergency department (ED) after...
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High-dose Vitamin C therapy in Methemoglobinemia

Lee KW, Kang TS, Park SY

  • KMID: 2333826
  • J Korean Soc Emerg Med.
  • 2014 Apr;25(2):202-205.
Methylene blue is the first choice antidote for management of methemoglobinemia, however, some patients are refractory to methylene blue and in most cases, methylene blue cannot be available instantly in...
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A Patient with "Rebound Methemoglobinemia" during Treatment of Methemoglobinemia Caused by Propanil Intoxication

Seon KH, Park YJ, Cho SH

  • KMID: 2333585
  • J Korean Soc Emerg Med.
  • 2013 Dec;24(6):775-779.
Methemoglobinemia results from the oxidation of ferrous iron (Fe++) to ferric iron (Fe+++) within hemoglobin. It is caused by various etiologies, including the herbicide Propanil. Patients with low levels of...
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Antidote for acquired methemoglobinemia: methylene blue

Lee KW, Lee JB

Methylene blue (MB) is an effective antidote for methemoglobinemia. MB is a basic dye, yielding a blue solution. In the human body, hemoglobin is the oxygen-carrying protein including a ferrous...
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Two Cases of Methemoglobinemia Induced by the Exposure to Nitrobenzene and Aniline

Lee CH, Kim SH, Kwon DH, Jang KH, Chung YH, Moon JD

  • KMID: 2379977
  • Ann Occup Environ Med.
  • 2013 ;25(1):31.
OBJECTIVE: To report two cases of methemoglobinemia induced by inhaled nitrobenzene and dermally absorbed aniline. METHODS: We have evaluated a 37-year-old male worker exposed to nitrobenzene by inhalation while conducting maintenance...
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Fatal Propanil Pesticide Poisoning Presenting with Methemoglobinemia

Woo SH, So BH, Choi KH, Park KN, Lee WJ

  • KMID: 1898816
  • J Korean Soc Emerg Med.
  • 2006 Jun;17(3):268-272.
Acute propanil pesticide poisoning is rare and propanil is known to have a low toxicity. Propanil metabolite induces the conversion of Fe2+ in hemoglobin to Fe3+, forming methemoglobin. Patients with...
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Relationship Between the Methemoglobin Level and Oxygen Saturation on a Pulse Oximeter in Cases of Acute Methemoglobinemia

Shim JC, Ryu HH, Lee YJ, Kim YS, Youm KI, Moon JM, Chun BJ, Min YI, Koh YS

  • KMID: 2193736
  • J Korean Soc Emerg Med.
  • 2005 Oct;16(5):588-594.
PURPOSE: Methemoglobinemia is a disorder caused by over accumulation of methemoglobin in the red blood cells of circulating blood, prohibiting adequate supply of oxygen to organs. The seriousness of its...
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Methemoglobinemia Associated with Diarrheal Disease before 2 Months of Age

Jung JA, Lee JW, Seo JW

  • KMID: 2335542
  • J Korean Pediatr Soc.
  • 2001 Dec;44(12):1387-1394.
PURPOSE: Methemoglobinemia has been observed during a diarrheal illness among those who were not exposed to oxidizing agents in neonates and young infants. We performed the study to determine predisposing...
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A Case of Congenital Methemoglobinemia Due to NADH-Methemoglobin Reductase Deficiency

Kim DH, Lee JA, Lee SJ, Jo HS, Lee YK, Park JD, Kim BI, Choi JH, Lee DS, Cho HI, Park KR

  • KMID: 1606285
  • J Korean Pediatr Soc.
  • 2001 Jun;44(6):699-704.
Congenital methemoglobinemia is caused by NADH-methemoglobin reductase deficiency in more than half of the total reported cases. NADH-methemoglobin reductase deficiency is an uncommon hereditary disorder producing methemoglobinemia and cyanosis in...
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Changes in Incidence of Infantile Transient Methemoglobinemia Associated with Infectious Diarrhea during 1989-1999 in Kyungnam Province

Kim YS, Kim EA, Lim JY, Choi MB, Park CH, Woo HO, Park BK, Youn HS, Jung YS, Lee DJ, Kim JH, Kim EJ, Kim CK

  • KMID: 2104497
  • J Korean Pediatr Soc.
  • 2000 Dec;43(12):1569-1575.
PURPOSE: Infantile transient methemoglobinemia(ITM) may develop in association with infectious diarrhea without exposure to any toxic oxidizing agents. We observed that the number of ITM associated with infectious diarrhea have...
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Inaccurate Reading of Pulse Oximeter Due to Methemoglobinemia: A case report

Kim KH, Choi HS

Pulse oximeters measure the arterial oxygenation by determining the color of the blood between a light source and a photodetector. The light source consists of two light-emitting diodes (LEDs) that...
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Clincal Features of Methemoglobinemia in Newborn Diarrhea Infant

Kim HG, Kim CS, Lee SL

  • KMID: 1898301
  • J Korean Soc Neonatol.
  • 1997 Nov;4(2):238-245.
PURPOSE: Newborn infants with diarrhea, metabolic acidosis and dehydration may develop methemoglobinemia without exposure to oxidizing agents. This study was undertaken to investigate clinical features in the development of methemoglobinemia...
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Effect of N-acetylcysteine on Dapsone-Induced Methemoglobinemia

Chang WJ, Kim SH, Lee HS

  • KMID: 2194612
  • J Korean Soc Emerg Med.
  • 1997 Jun;8(2):150-154.
BACKGROUND: To determine whether N-acetylcysteine(NAC) reduces methemoglobin. METHOD: We carried out an in vivo experiment in rats, weighed about 300g. Each rat was ingested 200mg of dapsone(4,4'diaminodiphenyl sulphone) to induce methemo-...
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A Case of Acute Hemolytic Anemia and Methemoglobinemia Induced by Massive Dapsone Intoxication

Seong NH, Kim YW, Heo WJ, Lim CH, Kim JS, Paek SK, Park KS, Lee CI

  • KMID: 2083358
  • Korean J Hematol.
  • 1997 May;32(1):106-111.
Dapsone toxicity is evidenced by varying clinical pictures ranging from deep cyanosis in an otherwise alert normal appearing individual to restlessness, dyspnea, extensive hemolytic anemia, methemoglobinemia, sulfhemoglobinemia and serious central...
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Analysis of Contaminated Ground Water Inducing Methemoglobinemia and Epidemiologic Investigation of Contaminated Ground Water

Lee BH, Suh JY, Kim NS, Lee H, Kim YY, Choi BY, park HB, Kim MY, Yeo IH

  • KMID: 2208306
  • J Korean Pediatr Soc.
  • 1995 Apr;38(4):507-512.
PURPOSE: Drining of Nitrate-contaminated water has been the most common cause of acquired methemoglobinemia. We had cyanotic infant diagnosed as methemoglobinemia caused by feeding with powdered formula mixed with nitrate-contaminated...
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