- Establishment of NOAEL for intracavernous injections of human bone marrow-derived mesenchymal stem cells in rats
-
Kim JK, Jang MJ, Kim BH, Choi KR, Song G, Shin HC, Suh N, Kim YM, You D, Ahn TY, Kim CS
- KMID: 2466797
- Investig Clin Urol.
- 2020 Jan;61(1):88-98.
- doi: 10.4111/icu.2020.61.1.88
PURPOSE: To assess the possible negative health effects of human bone marrow-derived mesenchymal stem cells (hBMSCs) on fertility and early embryonic development following intracavernous injections in rats. MATERIALS AND METHODS: A... -
- CITED
-
- Close
- SHARE
-
- Close
- Clinical Use of Mesenchymal Stem Cells in Bone Regeneration
-
Park CW, Lim SJ, Park YS
- KMID: 2469880
- J Korean Orthop Assoc.
- 2019 Dec;54(6):490-497.
- doi: 10.4055/jkoa.2019.54.6.490
Owing to the recent advances in biological knowledge on stem cells, many efforts are being made to apply them to clinical practice. Although mesenchymal stem cells were first found in... -
- CITED
-
- Close
- SHARE
-
- Close
- Optimization of Microenvironments Inducing Differentiation of Tonsil-Derived Mesenchymal Stem Cells into Endothelial Cell-Like Cells
-
Oh SY, Choi DH, Jin YM, Yu Y, Kim HY, Kim G, Park YS, Jo I
- KMID: 2467055
- Tissue Eng Regen Med.
- 2019 Dec;16(6):631-643.
- doi: 10.1007/s13770-019-00221-y
BACKGROUND: Stem cell engineering is appealing consideration for regenerating damaged endothelial cells (ECs) because stem cells can differentiate into EC-like cells. In this study, we demonstrate that tonsil-derived mesenchymal stem... -
- CITED
-
- Close
- SHARE
-
- Close
- Spreading Shape and Area Regulate the Osteogenesis of Mesenchymal Stem Cells
-
Zhao Y, Sun Q, Wang S, Huo B
- KMID: 2467050
- Tissue Eng Regen Med.
- 2019 Dec;16(6):573-583.
- doi: 10.1007/s13770-019-00213-y
BACKGROUND: Mesenchymal stem cells (MSCs) have strong self-renewal ability and multiple differentiation potential. Some studies confirmed that spreading shape and area of single MSCs influence cell differentiation, but few studies... -
- CITED
-
- Close
- SHARE
-
- Close
- Potential biomarkers and antagonists for fluoranthene-induced cellular toxicity of bone marrow derived mesenchymal stem cells
-
Hoque MM, Lee YE, Kim HR, Shin MG
- KMID: 2466590
- Blood Res.
- 2019 Dec;54(4):253-261.
- doi: 10.5045/br.2019.54.4.253
BACKGROUND: Fluoranthene (FR) is a common environmental pollutant that exists in a complex mixture with other polycyclic aromatic hydrocarbons (PAHs). We identified biomarkers for monitoring FR exposure and investigated the... -
- CITED
-
- Close
- SHARE
-
- Close
- MicroRNA-138 Suppresses Adipogenic Differentiation in Human Adipose Tissue-Derived Mesenchymal Stem Cells by Targeting Lipoprotein Lipase
-
Wang Y, Lin L, Huang Y, Sun J, Wang X, Wang P
- KMID: 2463798
- Yonsei Med J.
- 2019 Dec;60(12):1187-1194.
- doi: 10.3349/ymj.2019.60.12.1187
PURPOSE: Adipogenic differentiation of adipose tissue-derived mesenchymal stem cells (AMSCs) is critical to many disease-related disorders, such as obesity and diabetes. Studies have demonstrated that miRNA-138 (miR-138) is closely involved... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparison of the Cardiomyogenic Potency of Human Amniotic Fluid and Bone Marrow Mesenchymal Stem Cells
-
Jain M, Minocha E, Tripathy N, Singh N, Chaturvedi CP, Nityanand
- KMID: 2465885
- Int J Stem Cells.
- 2019 Nov;12(3):449-456.
- doi: 10.15283/ijsc18087
BACKGROUND AND OBJECTIVES: Most studies in cardiac regeneration have explored bone marrow mesenchymal stem cells (BM-MSC) with variable therapeutic effects. Amniotic fluid MSC (AF-MSC) having extended self-renewal and multi-potent properties... -
- CITED
-
- Close
- SHARE
-
- Close
- Immunosuppressive Effect of Exosomes from Mesenchymal Stromal Cells in Defined Medium on Experimental Colitis
-
Ma ZJ, Wang YH, Li ZG, Wang Y, Li BY, Kang HY, Wu XY
- KMID: 2465884
- Int J Stem Cells.
- 2019 Nov;12(3):440-448.
- doi: 10.15283/ijsc18139
BACKGROUND AND OBJECTIVES: The exosomes released by mesenchymal stromal cells (MSCs) in classical FBS-containing media have been demonstrated as an alternative, cell-free therapy in various diseases including inflammatory bowel disease... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effect of Mesenchymal Stem Cells Derived Microvesicles on the Treatment of Experimental CCL4 Induced Liver Fibrosis in Rats
-
Sabry D, Mohamed A, Monir M, Ibrahim HA
- KMID: 2465880
- Int J Stem Cells.
- 2019 Nov;12(3):400-409.
- doi: 10.15283/ijsc18143
BACKGROUND AND OBJECTIVES: The release of microvesicles (MVs) from mesenchymal stem cells (MSCs) has been implicated in intercellular communication, and may contribute to beneficial paracrine effects of stem cell-based therapies.... -
- CITED
-
- Close
- SHARE
-
- Close
- Improvement of Human Sperm Vacuolization and DNA Fragmentation Co-Cultured with Adipose-Derived Mesenchymal Stem Cell Secretome: In Vitro Effect
-
Bader R, Ibrahim JN, Mourad A, Moussa M, Azoury J, Azoury J, Alaaeddine N
- KMID: 2465879
- Int J Stem Cells.
- 2019 Nov;12(3):388-399.
- doi: 10.15283/ijsc19047
BACKGROUND AND OBJECTIVES: Oxidative stress (OS) is known to be an important factor of male infertility. Adipose-derived mesenchymal stem cells (AD-MSCs) are known to have immune-modulatory and anti-oxidant effects through... -
- CITED
-
- Close
- SHARE
-
- Close
- Frozen-thawed gelatin-induced osteogenic cell sheets of canine adipose-derived mesenchymal stromal cells improved fracture healing in canine model
-
Yoon Y, Jung T, Afan Shahid M, Khan IU, Kim WH, Kweon OK
- KMID: 2464079
- J Vet Sci.
- 2019 Nov;20(6):e63.
- doi: 10.4142/jvs.2019.20.e63
We assessed the efficacy of frozen-thawed gelatin-induced osteogenic cell sheet (FT-GCS) compared to that of fresh gelatin-induced osteogenic cell sheet (F-GCS) with adipose-derived mesenchymal stromal cells (Ad-MSCs) used as the... -
- CITED
-
- Close
- SHARE
-
- Close
- Safety and Biodistribution of Human Bone Marrow-Derived Mesenchymal Stromal Cells Injected Intrathecally in Non-Obese Diabetic Severe Combined Immunodefi ciency Mice: Preclinical Study
-
Quesada MP, GarcÃa-Bernal D, Pastor D, Estirado A, Blanquer M, GarcÃa-Hernández AM, Moraleda J, MartÃnez
- KMID: 2464072
- Tissue Eng Regen Med.
- 2019 Oct;16(5):525-538.
- doi: 10.1007/s13770-019-00202-1
BACKGROUND: Mesenchymal stromal cells (MSCs) have potent immunomodulatory and neuroprotective properties, and have been tested in neurodegenerative diseases resulting in meaningful clinical improvements. Regulatory guidelines specify the need to perform... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparison of Transforming Growth Factor-Beta1 and Lovastatin on Differentiating Mesenchymal Stem Cells toward Nucleus Pulposus-like Phenotype: An In Vitro Cell Culture Study
-
Yang SH, Yang KC, Chen CW, Huang TC, Sun YH, Hu MH
- KMID: 2461998
- Asian Spine J.
- 2019 Oct;13(5):705-712.
- doi: 10.31616/asj.2018.0257
STUDY DESIGN: In Vitro cell culture study. PURPOSE: This study aims to investigate the impact of transforming growth factor-beta1 (TGF-β1) and lovastatin on differentiating human mesenchymal stem cells (MSCs) toward nucleus... -
- CITED
-
- Close
- SHARE
-
- Close
- Mesenchymal Stem Cells Ameliorate Renal Inflammation in Adriamycin-induced Nephropathy
-
Kim HS, Lee JS, Lee HK, Park EJ, Jeon HW, Kang YJ, Lee TY, Kim KS, Bae SC, Park JH, Han SB
- KMID: 2461200
- Immune Netw.
- 2019 Oct;19(5):e36.
- doi: 10.4110/in.2019.19.e36
Mesenchymal stem cells (MSCs) ameliorate the renal injury in Adriamycin (ADR)-induced nephropathy, but the mechanisms underlying their efficacy remain incompletely understood. In this study, we demonstrated that MSCs increased the... -
- CITED
-
- Close
- SHARE
-
- Close
- Mesenchymal stem cells in acute myeloid leukemia: a focus on mechanisms involved and therapeutic concepts
-
Fathi E, Sanaat Z, Farahzadi
- KMID: 2459381
- Blood Res.
- 2019 Sep;54(3):165-174.
- doi: 10.5045/br.2019.54.3.165
Drug resistance in cancer, especially in leukemia, creates a dilemma in treatment planning. Consequently, studies related to the mechanisms underlying drug resistance, the molecular pathways involved in this phenomenon, and... -
- CITED
-
- Close
- SHARE
-
- Close
- Mesenchymal Stem Cell Transplantation Promotes Functional Recovery through MMP2/STAT3 Related Astrogliosis after Spinal Cord Injury
-
Kim C, Kim HJ, Lee H, Lee H, Lee SJ, Lee ST, Yang SR, Chung CK
- KMID: 2465902
- Int J Stem Cells.
- 2019 Jul;12(2):331-339.
- doi: 10.15283/ijsc18133
BACKGROUND AND OBJECTIVES: Treatment with mesenchymal stem cells (MSC) in spinal cord injury (SCI) has been highlighted as therapeutic candidate for SCI. Although astrogliosis is a major phenomenon after SCI,... -
- CITED
-
- Close
- SHARE
-
- Close
- A Novel Immunomodulatory Mechanism Dependent on Acetylcholine Secreted by Human Bone Marrow-derived Mesenchymal Stem Cells
-
Yi TG, Cho YK, Lee HJ, Kim J, Jeon MS, Ham DS, Kim WC, Song SU
- KMID: 2465901
- Int J Stem Cells.
- 2019 Jul;12(2):315-330.
- doi: 10.15283/ijsc18098
BACKGROUND AND OBJECTIVES: Mesenchymal stem cells (MSCs) are used to treat autoimmune or inflammatory diseases. Our aim was to determine the immunomodulatory mechanisms elicited by MSCs during inflammation. METHODS AND RESULTS:... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Bone Marrow-Derived Mesenchymal Stem Cells on Ischaemic-Reperfused Hearts in Adult Rats with Established Chronic Kidney Disease
-
Hamed GM, Morsy WE, Abd-El Hamid MS, Hassan AA, Abu Zahra
- KMID: 2465900
- Int J Stem Cells.
- 2019 Jul;12(2):304-314.
- doi: 10.15283/ijsc18114
BACKGROUND AND OBJECTIVES: Bone marrow-derived mesenchymal stem cells (BM-MSCs) are adult multipotent non-haematopoietic stem cells that have regeneration potential. The current study aimed to detect the ability of BM-MSCs to... -
- CITED
-
- Close
- SHARE
-
- Close
- Enhanced Anti-Cancer Effects of Conditioned Medium from Hypoxic Human Umbilical Cord–Derived Mesenchymal Stem Cells
-
Han KH, Kim AK, Jeong GJ, Jeon HR, Bhang SH, Kim DI
- KMID: 2465899
- Int J Stem Cells.
- 2019 Jul;12(2):291-303.
- doi: 10.15283/ijsc19002
BACKGROUND AND OBJECTIVES: There have been contradictory reports on the pro-cancer or anti-cancer effects of mesenchymal stem cells. In this study, we investigated whether conditioned medium (CM) from hypoxic human... -
- CITED
-
- Close
- SHARE
-
- Close
- FGF-17 from Hypoxic Human Wharton's Jelly-Derived Mesenchymal Stem Cells Is Responsible for Maintenance of Cell Proliferation at Late Passages
-
Han KH, Kim MH, Jeong GJ, Kim AK, Chang JW, Kim DI
- KMID: 2465898
- Int J Stem Cells.
- 2019 Jul;12(2):279-290.
- doi: 10.15283/ijsc18042
BACKGROUND AND OBJECTIVES: Although it is well known that hypoxic culture conditions enhance proliferation of human mesenchymal stem cells, the exact mechanism is not fully understood. In this study, we... -
- CITED
-
- Close
- SHARE
-
- Close
