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Effect of melatonin on the onset of puberty in male juvenile rats

Venugopal

Melatonin or N-acetyl-5-methoxytryptamine, the fascinating molecule secreted by the pineal gland. Melatonin has a close interaction with hypothalamic-pituitary-gonadal axis. In non-seasonal breeders like rat its exact role in reproduction is...
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A Patient with the Disrupted Sleep-Wake Rhythm after Traumatic Brain Injury

Kim E, Kim S, Lee JH

Many patients with a traumatic brain injury (TBI) experience a range of sleep problems. Although some studies investigated the pathophysiology of sleep-wake cycle disturbances in TBI patients, it has not...
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Changes of the Melatonergic System in Bipolar Disorder: A Literature Review

Lee JH, Moon E

Recently, melatonergic agents have been gaining much interest in the treatment of mood disorders. The elucidation of the underlying biological mechanisms related to the melatonergic system in mood disorders is...
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Melatonin inhibits nicotinic acetylcholine receptor functions in bovine chromaffin cells

Jo SH, Lee SH, Kim KT, Choi SY

Melatonin is a neurotransmitter that modulates various physiological phenomena including regulation and maintenance of the circadian rhythm. Nicotinic acetylcholine receptors (nAChRs) play an important role in oral functions including orofacial...
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The Evaluation of Exogenous Melatonin Administration in Supraspinatus Overuse Tendinopathy in an Experimental Rat Model

Kocadal O, Pepe M, Akyurek N, Gunes Z, Surer H, Aksahin E, Ogut B, Aktekin CN

BACKGROUND: Increased oxidative stress and inflammation play a critical role in the etiopathogenesis of chronic tendinopathy. Melatonin is an endogenous molecule that exhibits antioxidant and anti-inflammatory activity. The aim of...
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An Integrative Review on Alterations of Sleep after Cataract Surgery

An GJ

PURPOSE: The purpose of this study was to review previous literature with an aim to explore the sleep disturbance level after a patient undergoes cataract surgery using an integrative review. METHODS:...
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Chronic oral administration of Passiflora incarnata extract has no abnormal effects on metabolic and behavioral parameters in mice, except to induce sleep

Kim GH, Yi SS

Although the number of prescriptions and dependence on sleeping pills are increasing, the associations with unexpected abnormal behaviors and metabolic diseases caused by the overuse of sleeping pills are not...
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Live birth outcomes of vitrified embryos generated under growth hormone stimulation are improved for women categorized as poor-prognosis

Keane KN, Ye Y, Hinchliffe PM, Regan SL, Dhaliwal S, Yovich JL

OBJECTIVE: To determine the clinical pregnancy (CP) and live birth (LB) rates arising from frozen embryo transfers (FETs) that had been generated under the influence of in vitro fertilization (IVF)...
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Evaluation of drug interventions for the treatment of sleep disorders in children with autism spectrum disorders: a systematic review

Jenabi E, Ataei S, Bashirian

A structured review study of drug interventions on sleep disorders in patients with autism spectrum disorders (ASD) has not been published to date. This systematic review aimed to investigate drug...
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Tryptophan Metabolites in Irritable Bowel Syndrome: An Overnight Time-course Study

Burr RL, Gu H, Cain K, Djukovic D, Zhang X, Han C, Callan N, Raftery D, Heitkemper M

  • KMID: 2460485
  • J Neurogastroenterol Motil.
  • 2019 Oct;25(4):551-562.
  • doi: 10.5056/jnm19042
BACKGROUND/AIMS: Patients with irritable bowel syndrome (IBS) often report poor sleep quality. Whether poor sleep is associated with tryptophan (Trp) metabolites is unknown. We compared serum Trp metabolites in women...
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Does Melatonin and Melatonin Agonists Improve the Metabolic Side Effects of Atypical Antipsychotics?: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Igwe SC, Brigo F

Atypical antipsychotics (AAPs) are increasingly used for the treatment of psychotic disorders but are known to be associated with metabolic abnormalities. This study is a systematic review and meta-analysis of...
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Melatonin Rescues Mesenchymal Stem Cells from Senescence Induced by the Uremic Toxin p-Cresol via Inhibiting mTOR-Dependent Autophagy

Yun SP, Han YS, Lee JH, Kim SM, Lee SH

p-Cresol, found at high concentrations in the serum of chronic kidney failure patients, is known to cause cell senescence and other complications in different parts of the body. p-Cresol is...
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A Case of Circadian Rhythm Sleep-Wake Disorder in Partial Blindness

Kim H, Park J, Kim JB

Although it is well known that sleep disturbances can be developed in complete blindness, normally entrained circadian rhythm was observed in the majority of patients with partial blindness. Here, we...
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Field Study of Effects of Night Shifts on Cognitive Performance, Salivary Melatonin, and Sleep

Kazemi R, Motamedzade M, Golmohammadi R, Mokarami H, Hemmatjo R, Heidarimoghadam R

BACKGROUND: Night shift work is associated with many problems such as sleep deprivation, sleepiness, decreased cognitive performance, increased human errors, and fatigue. This study set out to measure cognitive performance,...
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Impact of Exposure to Dim Light at Night on Sleep in Female and Comparison with Male Subjects

Cho CH, Yoon HK, Kang SG, Kim L, Lee EI, Lee HJ

OBJECTIVE: Light pollution has become a social and health issue. We performed an experimental study to investigate impact of dim light at night (dLAN) on sleep in female subjects, with...
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Literature Review of Forest Healing Therapy on Korean Adults

Chae YR, Kim JH, Kang H

PURPOSE: This study was conducted to ascertain the effectiveness of forest healing therapy by analyzing researches on forest healing therapy applied to Korean adults and to confirm that forest healing...
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Melatonin for Treatment of Delirium in Hospitalized Patients : Retrospective Trial

Yang JW, Kim JW, Kang WS, Lee SM, Kim YJ, Paik JW

OBJECTIVES: Delirium is one of the most common mental illnesses that can affect cognitive function. Melatonin has been shown to be effective in the treatment of insomnia, and recent studies...
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Night shift preparation, performance, and perception: are there differences between emergency medicine nurses, residents, and faculty?

Richards J, Stayton TL, Wells JA, Parikh AK, Laurin EG

OBJECTIVE: Determine differences between faculty, residents, and nurses regarding night shift preparation, performance, recovery, and perception of emotional and physical health effects. METHODS: Survey study performed at an urban university medical...
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A Comparative Analysis of the Metabolic and Coagulative Profiles in Patients with Idiopathic Scoliosis, Congenital Scoliosis and Healthy Controls: A Case–Control Study

Ahuja K, Garg B, Chowdhuri , Yadav RK, Chaturvedi PK

STUDY DESIGN: Single-center, observational, case–control study. PURPOSE: Comparison and analysis of the metabolic and coagulative profiles in patients with idiopathic scoliosis, patients with congenital scoliosis, and healthy controls. OVERVIEW OF LITERATURE: Serum...
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The effect of melatonin on cardio fibrosis in juvenile rats with pressure overload and deregulation of HDACs

Wu Y, Si F, Luo L, Jing F, Jiang K, Zhou J, Yi Q

The effect of melatonin on juveniles with cardio fibrosis is poorly understood. We investigated whether HDACs participate in the anti-fibrotic processes regulated by melatonin during hypertrophic remodeling. Abdominal aortic constriction...
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