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Comparison of Metastatic Patterns Among Neuroendocrine Tumors, Neuroendocrine Carcinomas, and Nonneuroendocrine Carcinomas of Various Primary Organs

Park HK, Kwon GY

Background: Both neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs) exhibit neuroendocrine differentiation and are classified as neuroendocrine neoplasms (NENs). NECs and nonneuroendocrine neoplasms (non-NENs), such as adenocarcinoma, have similar mutational profiles....
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Cerebral Metastases in Appendiceal Cancer: Comprehensive Review and Report of Rare Medullary Carcinoma Histology

Mackel C, Rosenberg H, Varma H, Vega R, Stippler M

Appendiceal cancer is an extremely rare malignancy, and its metastatic spread to the brain is even more unusual. We describe a 47-year-old female who presented with a rare cerebral appendiceal...
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Concurrent Medullary Thyroid Carcinoma and Primary Thyroid Lymphoma (Diffuse Large B Cell Lymphoma): the First Case Report

Han Y, Kim YH, Kim HJ, Choi IH

Cases of simultaneously occurring medullary thyroid carcinoma (MTC) and lymphoma are extremely rare. An 84-year-old woman visited the hospital due to dyspnea, resulting from rapidly aggravated enlarged neck mass. Ultrasonography...
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Comparison of the Characteristics of Medullary Breast Carcinoma and Invasive Ductal Carcinoma

Park I, Kim J, Kim M, Bae SY, Lee SK, Kil WH, Lee JE, Nam SJ

PURPOSE: Medullary breast carcinomas (MBC) have been known to represent a rare breast cancer subtype associated with a more favorable prognosis than invasive ductal carcinomas (IDC). The purpose of this...
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A Case of Concurrent Papillary and Medullary Thyroid Carcinomas Detected as Recurrent Medullary Carcinoma after Initial Surgery for Papillary Carcinoma

Ahn D, Sohn JH, Park JY

As the prevalence of thyroid carcinoma is rapidly increasing, coexisting subtypes of thyroid carcinomas are often found. However, concurrent papillary and medullary carcinomas in the thyroid gland are extremely rare....
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Granular Cell Tumor of Thyroid Gland That Was Concomitant with Papillary Thyroid Carcinoma: A Case Report

Jang EJ, Seo AN, Lee SJ, Park JY

Granular cell tumor (GCT) of the thyroid is rare and histogenesis of the carcinoma still remains poorly understood. Here in this study, we report a case of perithyroidal granular cell...
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Clinicopathological Characteristics and Prognostic Factors of Medullary Thyroid Carcinoma

Jang HW, Lee JI, Hur KY, Kim JH, Kim SW, Min YK, Lee MS, Lee MK, Kim KW, Chung JH

BACKGROUND: Studies on the clinicopathological characteristics and prognostic factors of medullary thyroid carcinoma (MTC) in Korea are very rare. METHODS: We enrolled 56 MTC patients who underwent surgery at Samsung Medical...
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Clinical Analysis of Medullary Carcinoma of the Breast

Oh JW, Park S, Kim JH, Koo JS, Hur H, Yang WI, Park BW, Lee KS

PURPOSE: Medullary carcinoma of the breast is a variant of breast cancer characterized by the histologic appearance of poorly differentiated cells surrounded by a prominent lymphoid stroma. Medullary carcinoma has...
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DNA Copy Number Changes in Thyroid Medullary Carcinomas Determined by Comparative Genomic Hybridization

Kim HJ, Jee KJ, Shong YK, Hong SJ, Gong G

  • KMID: 1163282
  • Korean J Pathol.
  • 2008 Feb;42(1):27-32.
BACKGROUND: A point mutation in the RET proto-oncogene, in medullary thyroid carcinoma (MTC) is well known, but no other genetic causes of MTC have been found. This study was...
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Metastatic Medullary Carcinoma of Thyroid to Breast; A Case Initially Diagnosed as Primary Invasive Lobular Carcinoma: A Case Report

Lee Y, An J, Kim CH, Yeom BW, Choi JS, Chae YS

  • KMID: 1521616
  • Korean J Pathol.
  • 2007 Dec;41(6):412-415.
Metastasis to the breast from medullary carcinoma of the thyroid is extremely rare. We report a case of metastatic medullary carcinoma of the thyroid which presented as multiple breast masses...
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A Locally Advanced Breast Cancer with Difficult Differential Diagnosis of Carcinosarcoma and Atypical Medullary Carcinoma, which had Poor Response to Adriamycin- and Taxane-based Neoadjuvant Chemotherapy: A Case Report

Kim SH, Chung HC, Jeong J, Kim JH, Rha SY, Ahn JB, Cho NH, Jeung HC

  • KMID: 1522937
  • Cancer Res Treat.
  • 2007 Sep;39(3):134-137.
Atypical medullary carcinomas and carcinosarcoma have unique histopathological features. Here we present a case with a breast malignancy that had pathological characteristics of both. A 54-year old patient with a...
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Concurrence of Spatially Separated Medullary Carcinoma and Papillary Carcinoma of the Thyroid Gland: A Report of Three Cases

Yoo C, Jung CK, Kwon HS, Kim SH, Kim MS, Kim SN, Lee KY

  • KMID: 1521674
  • Korean J Pathol.
  • 2007 Jun;41(3):207-212.
Although medullary thyroid carcinoma (MTC) may coexist with papillary thyroid carcinoma (PTC) as a collision tumor within the same nodule or as two or more spatially separated tumors, these two...
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A Patient with Concurrent Medullary and Papillary Carcinoma of the Thyroid

Yoo SH, Lim KJ, Lee SH, Kim JH, Hong SH, Cho JH, Jung CK, Kwon HS, Yoon KH, Kim MS, Cha BY, Son HY

The origin of medullary thyroid carcinoma and papillary thyroid carcinoma are embryogenically different, so these tumors have been thought to be independent of each other. We experienced a case of...
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Analysis of RET Gene Point Mutation in a Family with Familial Medullary Thyroid Carcinoma

Lee KD, Mun HS, Kim JY, Chung H, Choi SH, Ha NW, Uchino S

  • KMID: 2276221
  • Korean J Otolaryngol-Head Neck Surg.
  • 2004 Sep;47(9):904-910.
BACKGROUND AND OBJECTIVES: Hereditary medullary thyroid carcinoma is presented as a part of MEN2A (65-75%) or MEN2B, but can also be inherited alone, which is called familial medullary thyroid carcinoma....
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Huge Exophytic Atypical Medullary Breast Cancer

Chang MC, Kim CD, Roh HR, Chae GB, Park WS, Min DW, Shin HS, Yang DH, Choi WJ

  • KMID: 2209892
  • J Korean Surg Soc.
  • 2003 Oct;65(4):353-355.
A medullary carcinoma of the breast is an uncommon breast cancer subtype, but has a fair prognosis. The histopathological criteria for a medullary carcinoma were delineated by Ridolfi et al....
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Multiple Endocrine Neoplasia Type IIa Report of three cases

Park JH, Lee HK, Nam SJ, Jung JH, Lee MS, Yang JH

  • KMID: 1895988
  • J Korean Surg Soc.
  • 2000 Jul;59(1):115-123.
PURPOSE: Multiple endocrine neoplasia (MEN) type IIa is a syndrome composed of pheochromocytoma, a medullary thyroid carcinoma, and parathyroid hyperplasia with autosomal dominant inheritance. The syndrome is rare, but has...
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Comparison of Adolescent Minimal Change Nephrotie Syndrome with Childood Minimal Change Nephrotic Syndrome

Choi CY, Kim JH, Kim PK

  • KMID: 1543942
  • J Korean Soc Pediatr Nephrol.
  • 1999 May;3(1):11-19.
Primary non-Hodgkin's lymphoma of the lung is rare among extranodal lymphomas. The most common form is low grade B-cell type originated from the mucosa-associated lymphoid tissue (MALT) of the lung...
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Concurrent Medullay and Papillary Carcinoma of the Thyroid

Hong SJ, Gong KY, Song YK, Ryu JS, Kim KS, Lee JH

  • KMID: 1944223
  • J Korean Soc Endocrinol.
  • 1998 Dec;13(4):634-639.
The origins of medullary carcinoma and papillary carcinoma of thyroid are embryologically different. We report a case of simultaneous occurrence of medullary carcinoma and papillary carcinoma of the thyroid in...
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Clinical Analysis of Typical Medullary Carcinoma of the Breast

Choi KH, Noh WC, Paik NS, Moon NM, Bang HY, Choi DW, Lee JI, Moon SM

  • KMID: 2175443
  • J Korean Cancer Assoc.
  • 1998 Feb;30(1):113-118.
PURPOSE: Medullary carcinoma of the breast is an uncommon subtype of infiltrating ductal carcinoma and its incidence in different series ranges between 2% and 8% of all breast canoers. The...
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Reclassification of the Medullary Carcinoma and It's Clinical Characteristics

Kim SK, Sohn CY, Kang KJ, Kim YS, Chang ES

  • KMID: 2059141
  • J Korean Cancer Assoc.
  • 1997 Oct;29(5):748-753.
PURPOSE: Reclassfication of the medullary carcinoma using a strict histologic criteria and analysis of the clinical and pathological characteristics of the medullary carcinoma. MATERIAL & METHODS: Thirty-seven cases of the...
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