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Increased Serum Activity of Matrix Metalloproteinase-9 in Patients with Acute Variceal Bleeding

Kwon OS, Jung HS, Bae KS, Jung YK, Kim YS, Choi DJ, Kim YS, Kim JH

  • KMID: 2284272
  • Gut Liver.
  • 2012 Apr;6(2):249-255.
BACKGROUND/AIMS: Matrix metalloproteinases (MMP)-2 and -9 can degrade essential components of vascular integrity. The aim of this study was to investigate the association between those MMPs and variceal bleeding (VB). METHODS:...
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The Plasma Level of Matrix Metalloproteinase (MMP)-2, -9 between Antepartum and Postpartum Period in Preeclampsia

Chang HJ, Yang JI, Kim HB, Kim HS, Ryu HS, Oh KS

  • KMID: 2077113
  • Korean J Obstet Gynecol.
  • 2004 Aug;47(8):1487-1491.
OBJECTIVE: To evaluate the changes of plasma MMP-2, -9 levels in preeclampsia between antepartum and postpartum periods, and compare with normotensive pregnant. METHODS: Plasma MMP-2, -9 levels were determined with enzyme-linked...
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The Correlation between Tear Matrix Metalloproteinase-9 Concentration and Clinical Findings in Dry Eye Disease

Kim HR, Lee HK

PURPOSE: To investigate the correlation between the matrix metalloproteinase-9 (MMP-9) concentration, and subjective symptoms and objective signs in dry eye patients. METHODS: We retrospectively reviewed the medical records of 134 eyes...
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Expression of Matrix Metalloproteinase-9 Correlates with Poor Prognosis in Human Malignant Fibrous Histiocytoma

Yoo J, Jung JH, Kang SJ, Kang CS

  • KMID: 2166130
  • Cancer Res Treat.
  • 2004 Dec;36(6):384-388.
PURPOSE: 92 kDa matrix metalloproteinase-9 (MMP-9) is believed to play an important role in degrading the matrix and basement membrane, contributing to the invasion and metastasis of malignant solid tumors....
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The Expression of Matrix Metalloproteinase-9 and Tumor Angiogenesis in Human Osteosarcoma

Yoo J, Jung JH, Choi HJ, Kang SJ, Lee A, Seo EJ, Shim SI, Kang CS

  • KMID: 2073757
  • Korean J Pathol.
  • 2005 Dec;39(6):418-423.
BACKGROUND: Matrix metalloproteinase-9 (MMP-9) is a matrix-degrading enzyme that's believed to play a crucial role not only for tumor invasion and metastasis, but also for a variety of stromal...
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Umbilical Cord Blood Matrix Metalloproteinase-9 Levels are associated with Funisitis

Shim SS, Kang HS, Maeng YH, Kim YD

PURPOSE: Intrauterine inflammation (IUI) is a leading cause of preterm delivery. Although matrix metalloproteinase-8 (MMP-8) and intercellular adhesion molecule-1 (ICAM-1) are known to be related with IUI, it has not...
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Study on Association between Single Nucleotide Polymorphisms of MMP7, MMP8, MMP9 Genes and Development of Gastric Cancer and Lymph Node Metastasis

Kim JH, Pyun JA, Lee KJ, Cho SW, Kwack KB

BACKGROUND/AIMS: Matrix metallopeptidase (MMP) is known to be involved in tumor invasion and metastasis of cancer. This study investigated the association of MMP7 rs11568818, MMP8 rs11225395, MMP9 rs17576 and rs2250889...
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Interaction of HIV-1 core p24 antigen with human monocytic cell line THP1 results in TNF-alpha dependent secretion of matrix metalloproteinase-9

Sung JH, Yoo SH, Park HK, Chong YH

  • KMID: 2001249
  • J Korean Soc Microbiol.
  • 2000 Feb;35(1):9-18.
Immunological mechanisms involving the release of inflammatory factors by HIV-1 infected microglia in the brain have been implicated in the pathogenesis of HIV dementia (HIVD). Since the regulation of matrix metalloproteinases (MMPs) activity...
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Novel Suppressive Effects of Ketotifen on Migration and Invasion of MDA-MB-231 and HT-1080 Cancer Cells

Kim HJ, Park MK, Kim SY, Lee CH

The high mortality rates associated with cancer reflect the metastatic spread of tumor cells from the site of their origin. Metastasis, in fact, is the cause of 90% of cancer...
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Functional Polymorphism in the Promoter Region of Matrix Metalloproteinase-9 is Strongly Associated with Acute Myocardial Infarction

Kim PJ, Chang K, Koh YS, Seung KB, Baek SH, Shin WS, Lim SH, Kim JH, Hong SJ, Choi KB

BACKGROUND AND OBJECTIVES: Matrix metalloproteinase-9 (MMP-9) plays an important role in the genesis of atherosclerotic plaque rupture and acute coronary syndrome (ACS), including an acute myocardial infarction (AMI). A single...
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The Pathogenesis of Adenomyosis Through the Immunohistochemical Study with bcl-2 and MMP-9

Han MS, Song GA, Jun HJ, Kim DC, Jeong JS

  • KMID: 2077149
  • Korean J Obstet Gynecol.
  • 2004 Sep;47(9):1714-1718.
OBJECTIVE: To understand the pathogenesis of adenomyosis through the immunohistochemical staining with bcl-2 and matrix metalloproteinase-9 (MMP-9) antibody. METHODS: We selected 45 cases of adenomyosis among the uterine specimens that were...
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Plasma Levels and Diagnostic Utility of Macrophage Colony-Stimulating Factor, Matrix Metalloproteinase-9, and Tissue Inhibitor of Metalloproteinases-1 as New Biomarkers of Breast Cancer

Lawicki S, Glazewska , Sobolewska M, Bedkowska , Szmitkowski M

BACKGROUND: Macrophage colony-stimulating factor (M-CSF), matrix metalloproteinase-9 (MMP-9), and its specific tissue inhibitor - tissue inhibitor of metalloproteinases-1 (TIMP-1) may play an important role in the pathogenesis and spread of...
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Expressions of E-cadherin, Cortactin and MMP-9 in Pseudoepitheliomatous Hyperplasia and Squamous Cell Carcinoma of the Head and Neck: Their Relationships with Clinicopathologic Factors and Prognostic Implication

You TK, Kim KM, Noh SJ, Bae JS, Jang KY, Chung MJ, Moon WS, Kang MJ, Lee DG, Park HS

BACKGROUND: E-cadherin, cortactin, and matrix metalloproteinase (MMP)-9 have roles in tumor development or progression, but their expression has not been fully investigated in pseudoepitheliomatous hyperplasia (PEH) and squamous cell carcinoma...
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Influence of Hepatocyte Growth Factor on its Receptor (c-met) expression and Invasion in HT Cell Line

Shin JC, Lee JH, Yang DE, Oh MJ, Moon HB, Lee Y, Kim SJ, Yi CS, Kim SP

  • KMID: 2262351
  • Korean J Obstet Gynecol.
  • 2001 Aug;44(8):1507-1513.
OBJECTIVE: To evaluate the invasive capacity of trophoblastic cells when treated with HGF, and see whether HGF induces c-met expression in vitro. METHODS: HT cell line was treated with recombinant HGF...
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Effects of Matrix Metalloproteinase Inhibitor on Ventilator-Induced Lung Injury in Rats

Kim JH, Park SY, Hur GY, Lee SH, Lee SY, Park SM, Suh IB, Shin C, Shim JJ, In KH, Kang KH, Yoo SH

BACKGROUND: Many inflammatory mediators and collagenases are involved in the pathogenesis of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). The increase of matrix metalloproteinase-9 (MMP-9, gelatinase-B) produced...
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Plasma Levels of Matrix Metalloproteinase-9 in Children With Chronic Spontaneous Urticaria

Dilek F, Ozceker D, Ozkaya E, Tamay Z, Yazici M, Kesgin S, Kocyigit A, Guler N

PURPOSE: Chronic spontaneous urticaria (CSU) is a disease that is primarily seen in adults and is comparatively rare in children. Consequently, only a few studies have focused on the pathogenesis...
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S100ß, Matrix Metalloproteinase-9, D-dimer, and Heat Shock Protein 70 Are Serologic Biomarkers of Acute Cerebral Infarction in a Mouse Model of Transient MCA Occlusion

Choi JI, Ha SK, Lim DJ, Kim SD, Kim SH

OBJECTIVE: Diagnosing acute cerebral infarction is crucial in determining prognosis of stroke patients. Although many serologic tests for prompt diagnosis are available, the clinical application of serologic tests is currently...
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Diagnosis of Acute Ischemic Stroke using Blood Biologic Markers in the Emergency Department

Yeo WH, Seo DW, Oh BJ, Kim W, Lim KS

  • KMID: 2332583
  • J Korean Soc Emerg Med.
  • 2008 Dec;19(6):731-737.
PURPOSE: In patients with acute neurological symptoms, brain computed tomography (CT) is usually used to exclude hemorrhagic stroke. After CT imaging, there is no rapid, effective biologic marker for differentiating...
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Genetics and Biomarkers of Moyamoya Disease: Significance of RNF213 as a Susceptibility Gene

Fujimura M, Sonobe S, Nishijima , Niizuma K, Sakata H, Kure S, Tominaga T

  • KMID: 2223711
  • J Stroke.
  • 2014 May;16(2):65-72.
Moyamoya disease is characterized by a progressive stenosis at the terminal portion of the internal carotid artery and an abnormal vascular network at the base of the brain. Although its...
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Effect of Helicobacter pylori Eradication According to the IL-8-251 Polymorphism in Koreans

Kang HY, Kim SG, Lee MK, Kim JS, Jung HC, Song IS

Previous studies suggested that polymorphisms of proinflammatory cytokine genes are important host genetic factors in Helicobacter pylori infection. The present study evaluated whether IL-8-251 polymorphism affected H. pylori eradication rate...
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