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The effect of periodontal flap surgery on Matrix metalloproteinases (MMPs) and Tissue inhibitors of matrix metalloproteinase-1 (TIMP-1) levels in gingival crevicular fluids of periodontitis patients

Kim JH, Ko JS, Kim HM, Kim TI, Seol YJ, Lee YM, Ku Y, Chung CP, Han SB, Rhyu IC

No abstract available.
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The Roles of Matrix Metalloproteinase-1, -2 in the Degenerative Spinal Diseases

Kim KY, Cho KH, Kim JY, Park SW, Ahn YH, Ahn YM, Yoon SH, Cho KG, Shim C

  • KMID: 1546445
  • J Korean Neurosurg Soc.
  • 2000 Feb;29(2):180-187.
No abstract available.
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The Effects of Hantaan Virus on Fibronectin and Matrix Metalloproteinase-3

Park HS

  • KMID: 1573029
  • J Bacteriol Virol.
  • 2002 Jun;32(2):195-202.
The clinical symptoms and signs of hemorrhagic fever with renal syndrome (HFRS) are well known, but the pathophysiology caused by Hantaan virus is not fully understood yet. This study was...
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Matrix Metalloproteinase-1 and Tissue Inhibitor of Metalloproteinase-1 levels in Exudative Pleural Effusions

Cho JH, Nam JH, Lee KH, Yoon BK, Ryu JS, Kwak SM, Lee HL

  • KMID: 2318695
  • Tuberc Respir Dis.
  • 2005 Nov;59(5):517-521.
BACKGROUND: The balances of the proteinases and antiproteinases system have been implicated in the pathogenesis of various exudative pleural effusions. The aim of this study was to examine the matrix...
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The Differential expression of matrix metalloproteinase and their tissue inhibitors in myometrium and leiomyoma

Yoo EH, Whang EM, Yu HK, Kim SB

  • KMID: 2261615
  • Korean J Obstet Gynecol.
  • 1999 Dec;42(12):2806-2814.
OBJECTIVES: To determine the level of mRNA expression of various members of the matrix metalloproteinase and tissue inhibitors in uterine leiomyoma compared with unaffected myometrium. Materials & Method: 30 cases of...
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Effects of Hepatocyte Growth Factor on Collagen Synthesis and Matrix Metalloproteinase Production in Keloids

Lee WJ, Park SE, Rah DK

Keloids are pathologic proliferations of the dermal layer of the skin resulting from excessive collagen production and deposition. Hepatocyte growth factor (HGF) increases the expression of matrix metalloproteinase (MMP)-1 and...
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Membrane-type Matrix Metalloproteinase-1 Induced Invasive and Angiogenic Activities in Chick Chorioallantoic Membrane (CAM) Model

Jeong JW, Sohn TK, Yu DY, Kim KW

  • KMID: 2007126
  • J Korean Cancer Assoc.
  • 2001 Feb;33(1):49-55.
PURPOSE: Matrix metalloproteinases (MMPs) have been reported to play critical roles in the endothelial cell migration and matrix remodeling during angiogenic process. To investigate the roles of the membrane type...
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Immunohistochemical study of metalloproteinase-1 and tissue inhibitor of matrix metalloproteinase-1, -2 in the idiopathic interstitial pneumonia

Kyung SY, Lim YH, An CH, Park JW, Jeong SH, Shin EK, Ha SY, Lee JW

  • KMID: 1620613
  • Korean J Med.
  • 2003 Aug;65(2):196-204.
BACKGROUND: In the idiopathic interstitial pneumonia (IIP), it has been known that imbalance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) is important factor for abnormal remodeling of...
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Changes of Matrix Metalloproteinase-9 and Tissue Inhibitor of Matrix Metalloproteinase-1 in Sputum from Moderate to Severe Acute Asthma after Corticosteroid Therapy

Lee JH, Lee JH, Song DY, Baek SH, Kang IJ

  • KMID: 2314400
  • Pediatr Allergy Respir Dis.
  • 2005 Dec;15(4):389-398.
PURPOSE: Bronchial asthma is an inflammatory respiratory disease characterized by the activation of inflammatory cells and its infiltration. It has been recently reported that MMP- 9 dose an importance role...
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Matrix metalloproteinase-9/tissue inhibitor of matrix metalloproteinase-1 in induced sputum of bronchial asthmatics

Kim CW, Kim HJ, Park JW, Hong CS

  • KMID: 1563749
  • J Asthma Allergy Clin Immunol.
  • 2000 Dec;20(6):916-926.
BACKGROUND: Bronchial asthma is a chronic inflammatory disease of the airways characterized by inflammatory cell infiltrations, which require extracellular matrix (ECM) breakdown and inflammatory cell migration. Airway remodeling with ECM...
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p-Coumaric Acid Attenuates UVB-Induced Release of Stratifin from Keratinocytes and Indirectly Regulates Matrix Metalloproteinase 1 Release from Fibroblasts

Seok JK, Boo YC

Ultraviolet (UV) radiation-induced loss of dermal extracellular matrix is associated with skin photoaging. Recent studies demonstrated that keratinocyte-releasable stratifin (SFN) plays a critical role in skin collagen metabolism by inducing...
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Effects of H2O2 and chlorhexidine on MMP-1, TIMP-1,2, Type 1 collagen, fibronectin and UNCL expressions in human periodontal ligament fibroblasts

Choi SM, Jang HS, Kim BO

PURPOSE: To evaulate the effects of chlorhexidine and H2O2 on matrix metalloproteinase-1 (MMP-1), tissue inhibitor of metalloproteinase(TIMP-1, TIMP-2), Type 1 collagen, fibronectin and UNCL expressions in human periodontal ligament fibroblasts...
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Esculetin Prevents the Induction of Matrix Metalloproteinase-1 by Hydrogen Peroxide in Skin Keratinocytes

Zhen AX, Piao MJ, Kang KA, Fernando P, Kang HK, Koh YS, Hyun JW

BACKGROUND: Reactive oxygen species (ROS) are involved in various cellular diseases. Excessive ROS can cause intracellular oxidative stress, resulting in a calcium imbalance and even aging. In this study, we...
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Characterization of the cytokine profile of platelet rich plasma (PRP) and PRP-induced cell proliferation and migration: Upregulation of matrix metalloproteinase-1 and -9 in HaCaT cells

Park HB, Yang JH, Chung KH

BACKGROUND: The underlying rationale of platelet rich plasma (PRP) therapy is that an injection of concentrated PRP at the site of injury may promote tissue repair via cytokine release from...
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Changes of Sputum Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinase-1 by Antibiotic Treatment in Acute Exacerbation of Chronic Bronchitis

Yoon HK, Ahn JH, Kim CH, Kwon SS, Kim YK, Kim KH, Moon HS, Park SH, Song JS

BACKGROUND: Excessive extracellular matrix (ECM) deposition by airway inflammation is presumed to play an important role in the pathogenesis of worsening airflow obstruction (Ed- acceptable three-word noun) seen during acute...
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Expression of Matrix-Metalloproteinase-2, Urokinase-Type Plasminogen Activator and Plasminogen Activator Inhibitor-1 in Invasion Mode and Lymph Node Metastasis of Laryngeal Squamous Cell Carcinoma

Jin SM, Lee SH, Choi G, Choi JO

  • KMID: 2274480
  • Korean J Otolaryngol-Head Neck Surg.
  • 1998 Sep;41(9):1169-1173.
BACKGROUND AND OBJECTIVES: Metastatic process of carcinoma cells involves dissolution of tumor matrix and penetration of the basement membrane (BM) which involves the active proteolysis of type IV collagen, proteoglycan,...
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Expression of matrix metalloproteinase-1 and -2 mRNA in retrodiscal tissue of the temporomandibular joint

Huh JK, Park KK, Choi MA, Kim HG

  • KMID: 2137008
  • J Korean Assoc Oral Maxillofac Surg.
  • 2003 Aug;29(4):212-218.
Matrix metalloproteinases (MMPs) play an important role in the normal morphogenesis, maintenance, and repair of matrix and also have important functions in pathologic conditions characterized by excessive degradation of extracellular...
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Effect of Vitamin C, Silicon and Iron on Collagen Synthesis and Break-Down Enzyme Expression in the Human Dermal Fibroblast Cell (HS27)

Kim JE, Lee J, Kim H, Kim J, Cho Y

Collagen is the major matrix protein in dermis and consists of proline and lysine, which are hydroxylated by prolyl hydroxylase (PH) and lysyl hydroxylase (LH) with cofactors such as vitamin...
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Effect of Relaxin Expression from an Alginate Gel-Encapsulated Adenovirus on Scar Remodeling in a Pig Model

Yun IS, Kang E, Ahn HM, Kim YO, Rah DK, Roh TS, Lee WJ, Yun CO

PURPOSE: Relaxin (RLX) is a transforming growth factor-β1 (TGF-β1) antagonist that is believed to function as a potent collagen re-arranger and a major suppressor of extracellular matrix components. Adenoviruses (Ads)...
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Differences in the Histopathology and Matrix Metalloproteinase Expression in Tenon's Tissue of Primary Open-Angle Glaucoma and Primary Angle-Closure Glaucoma

Seo JH, Park KH, Kim YJ, Yoo YC, Kang SH, Kim DM

PURPOSE: To investigate the differences in the histopathology and matrix metalloproteinase (MMP) expression in the Tenon's tissue of primary open-angle glaucoma (POAG) patients, primary angle-closure glaucoma (PACG) patients, and...
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