- Technique for orthotopic liver transplantation in cynomolgus monkeys (Macaca fascicularis)
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Lee KW, Cho CW, Park H, Choi GS, Park JB, Kim SJ
- KMID: 2405333
- Ann Surg Treat Res.
- 2018 Jan;94(1):8-12.
- doi: 10.4174/astr.2018.94.1.8
PURPOSE: Recent studies investigating new strategies to modulate the immune system have utilized animal models of liver transplantation (LT). However, the anhepatic phase (AHP) remains a crucial problem in LT.... -
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- Rectal Prolapse Associated with Recurrent Diarrhea in a Laboratory Cynomolgus Monkey (Macaca fascicularis)
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Lee SR, Lee YH, Kim KM, Kim SW, Jung KJ, Kim YH, Son HY, Chang KT
- KMID: 2114713
- Lab Anim Res.
- 2010 Dec;26(4):429-432.
- doi: 10.5625/lar.2010.26.4.429
Rectal prolapse is a protrusion of one or more layers of the rectum through the anus. A 5-year-old laboratory cynomolgus monkey who had suffered from recurrent diarrhea died after surgical... -
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- Reference values of hematological and biochemical parameters in young-adult cynomolgus monkey (Macaca fascicularis) and rhesus monkey (Macaca mulatta) anesthetized with ketamine hydrochloride
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Koo BS, Lee DH, Kang P, Jeong KJ, Lee S, Kim K, Lee Y, Huh JW, Kim YH, Park SJ, Jin YB, Kim SU, Kim JS, Son Y, Lee SR
- KMID: 2470106
- Lab Anim Res.
- 2019 Aug;35(2):39-44.
- doi: 10.1186/s42826-019-0006-0
Nonhuman primate models are valuable in biomedical research. However, reference data for clinical pathology parameters in cynomolgus and rhesus monkeys are limited. In the present study, we established hematologic and... -
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- A Histologic Demonstration of Siliceous Materials in Simian Lung Mite Infected Lung Tissues by Microincineration
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Kim JC, Kim MK
- KMID: 1089400
- J Vet Sci.
- 2003 Aug;4(2):117-123.
Approximately 90% of freshly imported macaques and other Old World Monkeys are known to be infected with respiratory mites. The lung associated pigments are integral components of pulmonary acariasis in... -
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- Evaluation of fecal microbiomes associated with obesity in captive cynomolgus monkeys (Macaca fascicularis)
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Koo BS, Hwang EH, Kim G, Oh H, Son Y, Lee D, Lim KS, Kang P, Lee S, Lee HY, Jeong KJ, Lee Y, Baek SH, Jeon CY, Park SJ, Kim YH, Huh JW, Jin YB, Kim SU, Lee SR, Hong JJ
- KMID: 2448703
- J Vet Sci.
- 2019 May;20(3):e19.
- doi: 10.4142/jvs.2019.20.e19
Microorganisms play important roles in obesity; however, the role of the gut microbiomes in obesity is controversial because of the inconsistent findings. This study investigated the gut microbiome communities in... -
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- Reference values of clinical pathology parameters in cynomolgus monkeys (Macaca fascicularis) used in preclinical studies
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Park HK, Cho JW, Lee BS, Park H, Han JS, Yang MJ, Im WJ, Park DY, Kim WJ, Han SC, Kim YB
- KMID: 2309080
- Lab Anim Res.
- 2016 Jun;32(2):79-86.
- doi: 10.5625/lar.2016.32.2.79
Nonhuman primates are increasingly used in biomedical research since they are highly homologous to humans compared to other rodent animals. However, there is limited reliable reference data of the clinical... -
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- Immobilization with Ketamine HCl and Tiletamine-Zolazepam in Cynomolgus Monkeys
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Lee JI, Hong SH, Lee SJ, Kim YS, Kim MC
- KMID: 1089411
- J Vet Sci.
- 2003 Aug;4(2):187-191.
To compare the effects of ketamine and tiletaminezolazepam (TZ) drugs widely used for the chemical restraint and immobilization of primates, on various physiological parameters and blood gas values in cynomolgus... -
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- Effect of Epinephrine or Pilocarpine on me Ocular Blood Flow
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Lee KW
- KMID: 2107643
- J Korean Ophthalmol Soc.
- 1990 Jun;31(6):767-771.
The ocular vascular resistance of the ciliary choroidal network has been investigated on measurements of pulse amplitude(PA). The ocular pulse is derived from the ciliary choroidal blood flow which account... -
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- Differential Cellular Tropism of Lentivirus and Adeno-Associated Virus in the Brain of Cynomolgus Monkey
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An H, Cho DW, Lee SE, Yang YS, Han SC, Lee CJ
- KMID: 2165578
- Exp Neurobiol.
- 2016 Feb;25(1):48-54.
- doi: 10.5607/en.2016.25.1.48
Many researchers are using viruses to deliver genes of interest into the brains of laboratory animals. However, certain target brain cells are not easily infected by viruses. Moreover, the differential... -
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- The Cholinergic and Adrenergic Nerve Innervation and Nerve Endings of the Iris Muscle in Monkeys
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Lee SH, Pak BG
- KMID: 2122539
- J Korean Ophthalmol Soc.
- 1975 Jun;16(2):91-98.
The cholinergic and adrenergic nerve innervation and nerve endings of the iris muscle in Cynomolgus monkey eye is studied by electron microscopy. In the iris, the sphincter muscle reveals nerve... -
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- Experimental autoimmune encephalomyelitis in cynomolgus monkeys
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Nam KH
- KMID: 1094651
- J Vet Sci.
- 2000 Dec;1(2):127-131.
Experimental autoimmune encephalomyelitis was induced in macaques. T cell clones infiltrated into the brain lesion area were compared with those in blood. Intradermal immunization of macaques with brain white matter... -
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- No expression of porcine endogenous retrovirus after pig to monkey xenotransplantation
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Hwang S, Jung YD, Cho K, Ock SA, Oh KB, Kim HS, Yun IJ, Ahn C, Park JK, Im S
- KMID: 1707449
- Lab Anim Res.
- 2014 Jun;30(2):90-93.
- doi: 10.5625/lar.2014.30.2.90
This study was performed to investigate the expression of two porcine endogenous retrovirus (PERV) elements, PERV gag and full-length conserved PERV, in blood cells collected periodically from organ-recipient monkeys that... -
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- Codelivery of IL-7 Augments Multigenic HCV DNA Vaccine-induced Antibody as well as Broad T Cell Responses in Cynomolgus Monkeys
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Park SH, Song MY, Nam HJ, Im SJ, Sung YC
- KMID: 2150675
- Immune Netw.
- 2010 Dec;10(6):198-205.
- doi: 10.4110/in.2010.10.6.198
BACKGROUND: A crucial limitation of DNA vaccines is its weak immunogenicity, especially in terms of eliciting antibody responses in non-human primates or humans; therefore, it is essential to enhance immune... -
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- Development and Evaluation of Acellular Dermal Matrix Originated from Transgenic Porcine Skin for Primates Skin Graft
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Lee KW, Choi GS, Kim MJ, Lee JS, Yoon H, Chun W
- KMID: 2361631
- J Korean Burn Soc.
- 2016 Dec;19(2):82-87.
- doi: 10.0000/jkbs.2016.19.2.82
This study was performed to compare the healing quality of the allogenic acellular dermal matix (ADM) and xenogenic ADM combined with autologous split thicknessskin graft. Xenogenic ADM was obtained from... -
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- Reference values of hematology, biochemistry, and blood type in cynomolgus monkeys from cambodia origin
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Choi K, Chang J, Lee MJ, Wang S, In K, Galano-tan WC, Jun S, Cho K, Hwang YH, Kim SJ, Park W
- KMID: 2312153
- Lab Anim Res.
- 2016 Mar;32(1):46-55.
- doi: 10.5625/lar.2016.32.1.46
Cynomolgus monkeys as nonhuman primates are valuable animal models because they have a high level of human gene homology. There are many reference values for hematology and biochemistry of Cynomolgus... -
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- Influence of Ovariectomy on Bone Turnover and Trabecular Bone Mass in Mature Cynomolgus Monkeys
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Iwamoto J, Seki A, Matsuura M, Sato Y, Takeda T, Matsumoto , Yeh JK
- KMID: 1758563
- Yonsei Med J.
- 2009 Jun;50(3):358-367.
- doi: 10.3349/ymj.2009.50.3.358
PURPOSE: To examine the influence of ovariectomy (OVX) on bone turnover and trabecular bone mass at the 3 clinically important skeletal sites in mature cynomolgus monkeys. MATERIALS AND METHODS: Six... -
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- Milk Transfer and Toxicokinetics of Valproic Acid in Lactating Cynomolgus Monkeys
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Lee JH, Yu WJ, Jeong EJ, Chung MK
- KMID: 2317816
- Toxicol Res.
- 2013 Mar;29(1):53-60.
Studies on milk transfer of drugs in non-human primates (NHPs) are among the crucial components in the assessment of peri- and postnatal toxicity because of the similarity between NHPs and... -
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- Non-invasive Myocardial Strain Imaging to Evaluate Graft Failure in Cardiac Xenotransplantation
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Yang HS, Chee HK, Kim JS, Kim WS, Park JH, Shin KC, Park KS, Lee SW, Cho KH, Park WJ, Oh KB, Ahn C, Yun IJ
- KMID: 2375677
- J Korean Soc Transplant.
- 2017 Mar;31(1):25-33.
- doi: 10.4285/jkstn.2017.31.1.25
BACKGROUND: The shortage of human hearts for allotransplantation makes xenotransplantation a possible option for controllable organ providers. To detect acute xenograft rejection, invasive biopsy seems inevitable; however, this occasionally results... -
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- Preclinical development of a humanized neutralizing antibody targeting HGF
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Kim H, Hong SH, Kim JY, Kim IC, Park YW, Lee SJ, Song SW, Kim JJ, Park G, Kim TM, Kim YH, Park JB, Chung J, Kim IH
- KMID: 2375796
- Exp Mol Med.
- 2017 Mar;49(3):e309.
- doi: 10.1038/emm.2017.21
Hepatocyte growth factor (HGF) and its receptor, cMET, play critical roles in cell proliferation, angiogenesis and invasion in a wide variety of cancers. We therefore examined the anti-tumor activity of... -
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