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The Nedd8-activating enzyme inhibitor MLN4924 suppresses colon cancer cell growth via triggering autophagy

Lv Y, Li B, Han K, Xiao Y, Yu X, Ma Y, Jiao Z, Gao J

Neddylation is a post-translational protein modification process. MLN4924 is a newly discovered pharmaceutical neddylation inhibitor that suppresses cancer growth with several cancer types. In our study, we first investigated the...
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Anti-arthritic activity of D-carvone against complete Freund’s adjuvant-induced arthritis in rats through modulation of inflammatory cytokines

Chen G, Song Y, Ma F, Ma Y

Chronic joint pain due to loss of cartilage function, degradation of subchondral bone, and related conditions are common plights of an arthritis patient. Antioxidant compounds could solve the problems in arthritic...
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A Novel De Novo Pathogenic Variant in FOXF1 in a Newborn with Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins

Ma Y, Jang MA, Yoo HS, Ahn SY, Sung SI, Chang YS, Ki CS, Park WS

Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is an autosomal dominant, fatal developmental disorder of the lungs, with a mortality rate of about 100%. ACD/MPV is caused by...
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The combination of deoxynivalenol and zearalenone at permitted feed concentrations causes serious physiological effects in young pigs

Chen F, Ma Y, Xue C, Ma J, Xie Q, Wang G, Bi Y, Cao Y

This study was to investigate the effects of the combination of deoxynivalenol (DON) and zearalenone (ZON) on pigs. Twenty-four weaning piglets were divided into a control group fed a diet...
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Radiomics of Non-Contrast-Enhanced T1 Mapping: Diagnostic and Predictive Performance for Myocardial Injury in Acute ST-Segment-Elevation Myocardial Infarction

Ma Q, Ma Y, Yu T, Sun Z, Hou Y

Objective: To evaluate the feasibility of texture analysis on non-contrast-enhanced T1 maps of cardiac magnetic resonance (CMR) imaging for the diagnosis of myocardial injury in acute myocardial infarction (MI). Materials and...
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Aberrant Forms of Escherichia coli in Urine Culture

Ma Y, Lee JH, Lee ST, Ki CS, Lee NY

Bacterial morphology can be altered by various factors, including antibiotics. Unusually shaped, large, swollen organisms were observed in a urine culture obtained from a patient who had no history of...
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Alternatively Polarized Macrophages Regulate the Growth and Differentiation of Ependymal Stem Cells through the SIRT2 Pathway

Ma Y, Deng M, Zhao Xq, Liu M

  • KMID: 2500526
  • Exp Neurobiol.
  • 2020 Apr;29(2):150-163.
  • doi: 10.5607/en19078
Ependymal stem cells (EpSCs) are dormant stem cells in the adult spinal cord that proliferate rapidly and migrate to the site of injury after spinal cord injury (SCI). Although they...
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Electrophysiologic Characteristics of Nitrous-Oxide-Associated Peripheral Neuropathy: A Retrospective Study of 76 Patients

Fang X, Yu M, Zheng D, Gao H, Li W, Ma Y

Background and Purpose The electrophysiologic characteristics of peripheral neuropathy secondary to nitrous oxide (N2O) abuse remain unclear. The paper therefore aimed to summarize the electrophysiologic characteristics of N2O-associated peripheral neuropathy...
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Efficacy and impact of PARPi monotherapy to subsequent platinum-based chemotherapy in BRCA1/2 mutant ovarian cancer patients with secondary platinum-sensitive relapse

Kun S, Ma Y, Bu H, Kong B

Objective The therapeutic effect of poly(ADP-ribose) polymerase inhibitors (PARPi) monotherapy compared with platinum-based chemotherapy, and the impact to subsequent platinum-based chemotherapy after PARPi resistance were inconclusive. Methods BRCA1/2 mutant ovarian cancer patients with...
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Prognostic Value of the Evolution of HER2-Low Expression after Neoadjuvant Chemotherapy

Ma Y, Zhu M, Zhang J, Lv M, Chen X, Liu Z

Purpose Patients with human epidermal growth factor receptor 2 (HER2)–low advanced breast cancer can benefit from trastuzumab deruxtecan. Given the unclear prognostic characteristics of HER2-low breast cancer, we investigated the...
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Efficacy of Different Number of XELOX or SOX Chemotherapy Cycles After D2 Resection for Stage III Gastric Cancer

Yu Y, Zhang Z, Meng Q, Wang K, Li Q, Ma Y, Yao Y, Sun J, Wang G

Purpose: We aimed to explore whether the prognosis of patients treated with capecitabine and oxaliplatin (XELOX) or S-1 and oxaliplatin (SOX) regimens who received fewer cycles of chemotherapy after D2...
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Acquired Factor X Deficiency in Light Chain Amyloidosis: A Report of 2 Korean Cases

Ma Y, Kwon EH, Lee JE, Kim K, Kim HJ, Kim SH

Amyloidosis is a heterogeneous group of diseases in which misfolding of extracellular proteins is the pathogenic factor. Light chain amyloidosis (AL) is the most common form of amyloidosis, and the...
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Serum leptin, adiponectin and endometrial cancer risk in Chinese women

Ma Y, Liu Z, Zhang Y, Lu B

OBJECTIVE: To investigate the relationship between serum concentrations of leptin or adiponectin, and endometrial carcinoma in Chinese women. METHODS: We conducted a case-control study of a total of 516 Chinese women...
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A Case with Multiple Fungal Coinfections in a Patient who Presented with Pancoast Syndrome

Jin H, Kim D, Choi Js, Huh HJ, Lee NY, Han J, Cho HW, Ma Y, Jeon TY, Yoo SY, Yoo KH, Koo HH, Kim YJ

Invasive fungal infection (IFI) is a serious threat to pediatric patients with cancer given high morbidity and mortality. We present an 18-year-old male with precursor T-cell lymphoblastic leukemia who developed...
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Outcomes of Anti-CD19 CAR-T Treatment of Pediatric B-ALL with Bone Marrow and Extramedullary Relapse

Wan X, Yang X, Yang F, Wang T, Ding L, Song L, Miao Y, Wang X, Ma Y, Luo C, Tang J, Gu L, Chen J, Tang Y, Lu J, Li B

Purpose Anti-CD19 chimeric antigen receptor T-cell immunotherapy (19CAR-T) has achieved impressive clinical results in adult and pediatric relapsed/refractory (r/r) B-lineage acute lymphoblastic leukemia (B-ALL). However, the application and effect of CAR-T...
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Anterior Gradient 3 Promotes Breast Cancer Development and Chemotherapy Response

Xu Q, Shao Y, Zhang J, Zhang H, Zhao Y, Liu X, Guo Z, Chong W, Gu F, Ma Y

Purpose Anterior gradient 3 (AGR3) belongs to human anterior gradient (AGR) family. The function of AGR3 on cancer remains unknown. This research aimed to investigate if AGR3 had prognostic values in...
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Mycobacterium vaccae induces a strong Th1 response that subsequently declines in C57BL/6 mice

Zhang L, Jiang Y, Cui Z, Yang W, Yue L, Ma Y, Shi S, Wang C, Wang C, Qian A

Mycobacterium (M.) vaccae is a fast-growing species of saprophytic bacteria that is widely distributed. To understand the host immune responses induced by M. vaccae isolated from bovine submaxillary lymph nodes,...
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Clinical Significance of Random Urinary Vanillylmandelic Acid in Patients with Neuroblastoma

Park E, Park H, Cho H, Ma Y, Lee SY, Lee JW, Yoo KH, Sung KW, Koo HH

BACKGROUND: To evaluate the value of random urinary vanillylmandelic acid (VMA) as a surrogate marker for monitoring tumor response and predicting outcome in patients with neuroblastoma (NB). METHODS: Medical records of...
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Integrin β1 in Adipose-Derived Stem Cells Accelerates Wound Healing via Activating PI3K/AKT Pathway

Wang Q, Zhang N, Hu L, Xi Y, Mi W, Ma Y

Background: This study aims to investigate the effect of integrin β1 on wound healing induced by adipose-derived stem cells (ADSCs), as well as the corresponding mechanism. Methods: Integrin β1 was overexpressed...
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Treatment Outcomes in Children and Adolescents with Relapsed or Progressed Solid Tumors: a 20-year, Single-Center Study

Cho HW, Lee JW, Ma Y, Yoo KH, Sung KW, Koo HH

BACKGROUND: By estimating the survival rates and exploring prognostic factors in pediatric patients with relapsed or progressed solid tumors, our purpose was to generate background data for future studies. METHODS: We...
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