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Role of Interleukin-7 in the Development of and Recovery from Radiation-Induced Lymphopenia: A Post-hoc Analysis of a Prospective Cohort

Byun HK, Chung SY, Kim KJ, Seong J

Purpose Radiation-induced lymphopenia is associated with worse outcomes in solid tumors. We assessed the impact of interleukin-7 (IL-7), a key cytokine in lymphocyte homeostasis, on radiation-induced lymphopenia. Materials and Methods A...
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Role of Biochemical Nutritional Parameters as Predictors of Postoperative Morbidity in Major Spine Surgeries

Sugumar D, Arockiaraj J, Amritanand R, David KS, Krishnan V

Study Design: Prospective cohort study. Purpose: To evaluate the association between nutritional parameters related to postoperative surgical site infections and duration of hospital stay and intensive care unit (ICU) stay in...
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Association between absolute lymphocyte count and overall mortality in patients with surgically resected gastric cancer

Park SJ, Lee J, Kim H, Shin K, Lee M, Park JM, Choi MG, Park CH, Song KY, Lee HH, Kim IH

Background/Aims: Lymphocytes are an important component of the cell-mediated immune system. As lymphopenia is reportedly associated with poor prognoses in patients with various cancers, we investigated this notion in patients...
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The role of the neutrophil-to-lymphocyte ratio for the prediction severity in women with acute pyelonephritis in the emergency department

Song BH, Park SH, So BH, Kim SH, Zhu J, Choi SP, Oh JH

  • KMID: 2511369
  • J Korean Soc Emerg Med.
  • 2020 Dec;31(6):562-569.
Objective: It is difficult to predict medical outcomes for acute pyelonephritis (APN) in women. A delay in diagnosis and treatment results in rapid progression to circulatory collapse, multiple organ failure,...
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Effect of Cumulative Dexamethasone Dose during Concomitant Chemoradiation on Lymphopenia in Patients with Newly Diagnosed Glioblastoma

Lee C, Ahn S, Park JS, Song JH, Hong YK, Jeun SS

Background Lymphopenia frequently occurs after concomitant chemoradiation (CCRT) in patients with glioblastoma (GBM) and is associated with worse overall survival (OS). A few studies have tried to identify risk factors...
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Hypoalbuminemia and obesity class II are reliable predictors of peri-prosthetic joint infection in patient undergoing elective total knee arthroplasty

Man SLC, Chau WW, Chung KY, Ho KKW

Background:Malnutrition is a common and modifiable risk factor for postoperative complications and adverse outcomes in orthopedics. The purpose of this study was to identify biomarkers of malnutrition in patients undergoing...
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Usefulness of the neutrophil-to-lmphocyte ratio as a prognostic predictor in elderly patients admitted to the intensive care unit through emergency department

Kim SK, Park JH, Oh S, Park SH, Kim HJ, Kim SH, Kim SW, Zhu J, Choi SP, Oh JH

OBJECTIVE: The purpose of this study was to test the hypothesis that an increase in the neutrophil-to-lymphocyte ratio (NLR) increases the risk of in-hospital density in patients aged 65 and...
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The Platelet-to-Lymphocyte Ratio as an Inflammatory Marker in Rheumatic Diseases

Gasparyan , Ayvazyan L, Mukanova U, Yessirkepov M, Kitas GD

The platelet-to-lymphocyte ratio (PLR) has emerged as an informative marker revealing shifts in platelet and lymphocyte counts due to acute inflammatory and prothrombotic states. PLR has been extensively examined in...
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The Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Are Prognostic Factors in Patients with Locally Advanced Pancreatic Cancer Treated with Chemoradiotherapy

Lee BM, Chung SY, Chang JS, Lee KJ, Seong J

BACKGROUND/AIMS: We investigated whether inflammatory markers such as neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) independently and in combination would be significant prognostic factors for survival in patients with locally...
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Clinical Course of Childhood Immune Thrombocytopenic Purpura and Analysis Predicting Factor of Prognosis

Lee T, Choi J, Lim YJ

BACKGROUND: Immune thrombocytopenic purpura (ITP) is an acquired bleeding disorder in which the immune system destroys platelets. There were many studies which predicted the factors associated with the prognosis of...
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Relationships of Total Lymphocyte Count and Subpopulation Lymphocyte Counts with the Nutritional Status in Patients Undergoing Hemodialysis/Peritoneal Dialysis

Kim YN, Shin HS

OBJECTIVES: Dialysis patients' nutritional indicators are quite subjective and complex and cannot be easily measured in clinical settings. Based on previous reports that total lymphocyte count (TLC) and subpopulation lymphocyte...
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Trend of CD4+ Cell Counts at Diagnosis and Initiation of Highly Active Antiretroviral Therapy (HAART): Korea HIV/AIDS Cohort Study, 1992-2015

Kim MJ, Chang HH, Kim SI, Kim YJ, Park DW, Kang C, Kee MK, Choi JY, Kim SM, Choi BY, Kim WJ, Kim JM, Choi JY, Choi YH, Lee JS, Kim SW, Korea HIV/AIDS Cohort Study

BACKGROUND: CD4+ cell counts reflect immunologic status of human immunodeficiency virus (HIV) patients. Recommended CD4+ cell counts for the initiation of highly active antiretroviral therapy (HAART) has increased over the...
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Effects of Antiretroviral Therapy on the Survival of Human Immunodeficiency Virus-positive Adult Patients in Andhra Pradesh, India: A Retrospective Cohort Study, 2007-2013

Bajpai R, Chaturvedi H, Jayaseelan L, Harvey P, Seguy N, Chavan L, Raj P, Pandey A

OBJECTIVES: The survival outcomes of antiretroviral treatment (ART) programs have not been systematically evaluated at the state level in India. This retrospective study assessed the survival rates and factors associated...
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Sustaining Blood Lymphocyte Count during Preoperative Chemoradiotherapy as a Predictive Marker for Pathologic Complete Response in Locally Advanced Rectal Cancer

Heo J, Chun M, Noh OK, Oh YT, Suh KW, Park JE, Cho O

PURPOSE: The objective of this study was to explore the relationship between the circulating lymphocyte level during preoperative chemoradiotherapy (CRT) and pathologic complete response (pCR) in locally advanced rectal cancer. MATERIALS...
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Frequency of Skin Disorders in HIV-infected Patients and Their Relationship to CD4+ T Lymphocyte Counts

Kim MS, Ahn JY, Shin HS, Park MY

  • KMID: 1864402
  • Korean J Dermatol.
  • 2013 Oct;51(10):771-775.
BACKGROUND: Skin disorders are common in human immunodeficiency virus (HIV)-infected patients in Korea. However, introduction of highly active antiretroviral therapy (HAART) has changed the skin manifestations of HIV infection. OBJECTIVE: We...
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Implication of Early Lymphocyte Recovery after Allogeneic Hematopoietic Stem Cell Transplantation in Children with Leukemia

Han DK, Baek HJ, Kim SY, Hwang TJ, Kook H

PURPOSE: The repopulating lymphocytes after allogeneic hematopoietic stem cell transplantation have an important role not only on the prevention of serious infections in the early transplantation period, but also on...
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The Nutritional Assessment in Children: Understanding of Anthropometric Assessment and Biochemical Indexes in Children

Park KY

  • KMID: 1469219
  • Korean J Pediatr Gastroenterol Nutr.
  • 2009 Nov;12(Suppl 1):S6-S11.
Nutritional assessment is based on anthropometric, clinical, dietary and biochemical data. There is a lack of studies about the propriety of biochemical indexes for the nutritional assessment in children despite...
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Analysis of Otorhinolaryngologic Disease in Patients with Human Immunodeficiency Virus Infection

Cho KS, Lee DG, Park YD, Shin SC, Lee SH, Roh HJ

BACKGROUND AND OBJECTIVES: As human immunodeficiency virus (HIV) infection increases in prevalence and new medical therapies prolong the survival of HIV-infected patients, otolaryngologists will see a larger number of patients...
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Microscopic Colitis: The Pathologic Features of 24 Korean Patients

Lee SA, Kang MJ, Jung SA, Koo H

  • KMID: 2073792
  • Korean J Pathol.
  • 2009 Apr;43(2):133-138.
BACKGROUND: The clinical presentation of microscopic colitis (MC) consists of chronic non-bloody watery diarrhea for weeks or months at a time, abdominal pain, and changes in bowel habits with a...
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The Prognostic Value of the Preoperative Lymphocyte Count in Patients with Gastric Cancer

Kang SY, Yu WS, Chung HY, Park SH

  • KMID: 2372934
  • J Korean Gastric Cancer Assoc.
  • 2009 Mar;9(1):26-30.
PURPOSE: The aim of this study was to evaluate the prognostic value of the peripheral blood lymphocyte count before surgery in those patients with gastric cancer. MATERIALS AND METHODS: The study...
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