- Picropodophyllotoxin Inhibits Cell Growth and Induces Apoptosis in Gefitinib-Resistant Non-Small Lung Cancer Cells by Dual-Targeting EGFR and MET
-
Lee JY, Kang BY, Jung SJ, Kwak AW, Lee SO, Park JW, Joo SH, Yoon G, Lee MH, Shim JH
- KMID: 2539589
- Biomol Ther.
- 2023 Mar;31(2):200-209.
- doi: 10.4062/biomolther.2022.113
Patients with non-small-cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) amplification or sensitive muta-tions initially respond to the tyrosine kinase inhibitor gefitinib, however, the treatment becomes less effective... -
- CITED
-
- Close
- SHARE
-
- Close
- Real-World Study of Osimertinib in Korean Patients with Epidermal Growth Factor Receptor T790M Mutation–Positive Non–Small Cell Lung Cancer
-
Lee JH, Kim EY, Park CK, Lee SY, Lee Mk, Yoon SH, Lee JE, Lee SH, Kim SJ, Lee SY, Lim JH, Jang TW, Jang SH, Lee KY, Lee SH, Yang SH, Park DW, Park CK, Kang HS, Yeo CD, Choi CM, Lee JC
- KMID: 2537997
- Cancer Res Treat.
- 2023 Jan;55(1):112-122.
- doi: 10.4143/crt.2022.381
Purpose Although osimertinib is the standard-of-care treatment of epidermal growth factor receptor (EGFR) T790M mutation–positive non–small cell lung cancer, real-world evidence on the efficacy of osimertinib is not enough to... -
- CITED
-
- Close
- SHARE
-
- Close
- Concurrent Primary Carcinoma and Metastatic Lesions of the Thyroid
-
Lee JS, Lee JS, Yun HJ, Lee YS, Chang HS
- KMID: 2538527
- J Endocr Surg.
- 2022 Dec;22(4):127-130.
- doi: 10.16956/jes.2022.22.4.127
The thyroid gland is an infrequent site of metastases from other primary sites. Furthermore, concurrent primary carcinoma and metastatic disease of the thyroid gland is extremely rare. We report a case... -
- CITED
-
- Close
- SHARE
-
- Close
- Association of Fluorodeoxyglucose Positron Emission Tomography Radiomics Features with Clinicopathological Factors and Prognosis in Lung Squamous Cell Cancer
-
Erol M, Önner H, Küçükosmanoğlu
- KMID: 2537090
- Nucl Med Mol Imaging.
- 2022 Dec;56(6):306-312.
- doi: 10.1007/s13139-022-00774-2
Aim To evaluate the role of fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) radiomics features (RFs) for predicting clinicopathological factors (CPFs) and prognosis in patients with resected lung squamous... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Afatinib for Lung Cancer on Papillary Thyroid Carcinoma
-
Cho SH, Lee JS, Yun HJ, Lee YS, Chang HS
- KMID: 2536500
- Int J Thyroidol.
- 2022 Nov;15(2):131-134.
- doi: 10.11106/ijt.2022.15.2.131
Papillary thyroid carcinoma is the most common type of thyroid cancer, for which surgery following preoperative staging and risk assessment is the standard treatment. Afatinib is an orally active irreversible... -
- CITED
-
- Close
- SHARE
-
- Close
- Adverse Effects of Air Pollution on Pulmonary Diseases
-
Ko UW, Kyung SY
- KMID: 2533835
- Tuberc Respir Dis.
- 2022 Oct;85(4):313-319.
- doi: 10.4046/trd.2022.0116
Environmental exposure to air pollution is known to have adverse effects on various organs. Air pollution has greater effects on the pulmonary system as the lungs are directly exposed to... -
- CITED
-
- Close
- SHARE
-
- Close
- Artificial Intelligence-Based Identification of Normal Chest Radiographs: A Simulation Study in a Multicenter Health Screening Cohort
-
Yoo H, Kim EY, Kim H, Choi YR, Kim MY, Hwang SH, Kim YJ, Cho YJ, Jin KN
- KMID: 2533353
- Korean J Radiol.
- 2022 Oct;23(10):1009-1018.
- doi: 10.3348/kjr.2022.0189
Objective: This study aimed to investigate the feasibility of using artificial intelligence (AI) to identify normal chest radiography (CXR) from the worklist of radiologists in a health-screening environment. Materials and Methods:... -
- CITED
-
- Close
- SHARE
-
- Close
- Lazertinib: on the Way to Its Throne
-
Lee J, Hong MH, Cho BC
- KMID: 2532714
- Yonsei Med J.
- 2022 Sep;63(9):799-805.
- doi: 10.3349/ymj.2022.63.9.799
Lazertinib is an oral, irreversible, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that forms an irreversible covalent bond to the Cys797 residue in the ATP-binding site of... -
- CITED
-
- Close
- SHARE
-
- Close
- Survival Outcomes and Predictors for Recurrence of Surgically Treated Brain Metastasis From Non-Small Cell Lung Cancer
-
Byun J, Kim JH, Kim M, Lee S, Kim YH, Hong CK, Kim JH
- KMID: 2532251
- Brain Tumor Res Treat.
- 2022 Jul;10(3):172-182.
- doi: 10.14791/btrt.2022.0016
Background There are numerous factors to consider in deciding whether to undergo surgical treatment for brain metastasis from lung cancer. Herein, we aimed to analyze the survival outcome and predictors... -
- CITED
-
- Close
- SHARE
-
- Close
- Clinical Efficacy of Immune Checkpoint Inhibitors in Non–Small Cell Lung Cancer Patients with Liver Metastases: A Network Meta-Analysis of Nine Randomized Controlled Trials
-
Yin Q, Dai L, Sun R, Ke P, Liu L, Jiang B
- KMID: 2531326
- Cancer Res Treat.
- 2022 Jul;54(3):803-816.
- doi: 10.4143/crt.2021.764
Purpose This network meta-analysis (NMA) was conducted to compare the efficacy of immune checkpoint inhibitors in advanced non–small cell lung cancer (NSCLC) patients with liver metastases. Materials and Methods English literature... -
- CITED
-
- Close
- SHARE
-
- Close
- The Feasibility of Using Biomarkers Derived from Circulating Tumor DNA Sequencing as Predictive Classifiers in Patients with Small-Cell Lung Cancer
-
Feng Y, Liu Y, Yuan M, Dong G, Zhang H, Zhang T, Chang L, Xia X, Li L, Zhu H, Xing P, Wang H, Shi Y, Wang Z, Hu X
- KMID: 2531322
- Cancer Res Treat.
- 2022 Jul;54(3):753-766.
- doi: 10.4143/crt.2021.905
Purpose To investigate the feasibility of biomarkers based on dynamic circulating tumor DNA (ctDNA) to classify small cell lung cancer (SCLC) into different subtypes. Materials and Methods Tumor and longitudinal... -
- CITED
-
- Close
- SHARE
-
- Close
- Diagnosis of Lung Cancer in a Patient with Chronic Knee Pain Caused by Hypertrophic Osteoarthropathy
-
Heo DJ, Kang JH, Cho BJ, Kim JM
- KMID: 2530778
- Clin Pain.
- 2022 Jun;21(1):46-49.
- doi: 10.35827/cp.2022.21.1.46
Patients with chronic knee pain are common, and symptoms are usually caused by degenerative disorders of the knee joint. Although hypertrophic osteoarthropathy (HOA) is a rare cause of knee pain... -
- CITED
-
- Close
- SHARE
-
- Close
- Epithelial-Mesenchymal Transition-Inducing Factors Involved in the Progression of Lung Cancers
-
Nam MW, Kim CW, Choi KC
- KMID: 2529886
- Biomol Ther.
- 2022 May;30(3):213-220.
- doi: 10.4062/biomolther.2021.178
Although there have been advances in cancer therapy and surgical improvement, lung cancer has the lowest survival rate (19%) at all stages. This is because most patients are diagnosed with... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparison of the Predictive Power of a Combination versus Individual Biomarker Testing in Non–Small Cell Lung Cancer Patients Treated with Immune Checkpoint Inhibitors
-
Kim H, Kwon HJ, Kim ES, Kwon S, Suh KJ, Kim SH, Kim YJ, Lee JS, Chung JH
- KMID: 2528212
- Cancer Res Treat.
- 2022 Apr;54(2):424-433.
- doi: 10.4143/crt.2021.583
Purpose Since tumor mutational burden (TMB) and gene expression profiling (GEP) have complementary effects, they may have improved predictive power when used in combination. Here, we investigated the ability of... -
- CITED
-
- Close
- SHARE
-
- Close
- A Case of Lichenoid Drug Eruption in a Patient Treated with Pembrolizumab for Lung Cancer
-
Kim D, Kim SM, Park SH, Hong D, Lee Y, Seo YJ, Jung KE
- KMID: 2527686
- Korean J Dermatol.
- 2022 Mar;60(3):194-195.
-
- CITED
-
- Close
- SHARE
-
- Close
- Optimal positive lymph node ratio showing the benefit of postoperative radiotherapy in pathologic N2 non-small cell lung cancer: an exploratory study using the Surveillance, Epidemiology, and End Results data
-
Lee S, Noh OK
- KMID: 2527627
- Radiat Oncol J.
- 2022 Mar;40(1):37-44.
- doi: 10.3857/roj.2021.00969
Purpose: This study aimed to identify the clinical parameters having the beneficial effect of postoperative radiotherapy (PORT) in pathologic N2 (pN2) non-small cell lung cancer (NSCLC) using the Surveillance, Epidemiology,... -
- CITED
-
- Close
- SHARE
-
- Close
- Immunomodulatory effect of splenectomy in lung cancer mouse xenograft models receiving radiation therapy
-
Kim Y, Choi C, Park JH, Ahn WG, Shin SW, Kim SY, Noh JM
- KMID: 2527629
- Radiat Oncol J.
- 2022 Mar;40(1):53-65.
- doi: 10.3857/roj.2021.00885
Purpose: This study aims to investigate the effect of splenectomy on radiation-mediated growth inhibition and immune modulation in lung cancer xenograft models. Materials and Methods: Human non-small cell lung cancer... -
- CITED
-
- Close
- SHARE
-
- Close
- MEG3 LncRNA from Exosomes Released from Cancer-Associated Fibroblasts Enhances Cisplatin Chemoresistance in SCLC via a MiR-15a-5p/CCNE1 Axis
-
Sun Y, Hao G, Zhuang M, Lv H, Liu C, Su K
- KMID: 2526555
- Yonsei Med J.
- 2022 Mar;63(3):229-240.
- doi: 10.3349/ymj.2022.63.3.229
Purpose: Long non-coding RNAs (lncRNAs) may act as oncogenes in small-cell lung cancer (SCLC). Exosomes containing lncRNAs released from cancer-associated fibroblasts (CAF) accelerate tumorigenesis and confer chemoresistance. This study aimed... -
- CITED
-
- Close
- SHARE
-
- Close
- Clinical Features, Treatments, and Prognosis of Intramedullary Spinal Cord Metastases From Lung Cancer: A Case Series and Systematic Review
-
Wu L, Wang L, Yang J, Jia W, Xu Y
- KMID: 2528379
- Neurospine.
- 2022 Mar;19(1):65-76.
- doi: 10.14245/ns.2142910.455
Objective: Intramedullary spinal cord metastasis from lung cancer (ISCM-LC) are increasing in prevalence. We aim to investigate its clinical features, treatments and prognosis. Methods: We reported 6 ISCM-LC cases and conducted... -
- CITED
-
- Close
- SHARE
-
- Close
- Gallic Acid Hindered Lung Cancer Progression by Inducing Cell Cycle Arrest and Apoptosis in A549 Lung Cancer Cells via PI3K/Akt Pathway
-
Ko EB, Jang YG, Kim CW, Go RE, Lee HK, Choi KC
- KMID: 2526817
- Biomol Ther.
- 2022 Mar;30(2):151-161.
- doi: 10.4062/biomolther.2021.074
This study elucidates the anti-cancer potential of gallic acid (GA) as a promising therapeutic agent that exerts its effect by regulating the PI3K/Akt pathway. To prove our research rationale, we... -
- CITED
-
- Close
- SHARE
-
- Close
