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Renal Effects of Prostaglandins and Cyclooxygenase-2 Inhibitors

Kim GH

Prostaglandins (PGs) with best-defined renal functions are PGE2 and prostacyclin (PGI2). These vasodilatory PGs increase renal blood flow and glomerular filtration rate under conditions associated with decreased actual or effective...
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Effect of Furosemide on the Renal Guanylate Cyclase in Rat

Kim HS, Chun CS

  • KMID: 1912430
  • Korean J Urol.
  • 1987 Aug;28(4):488-494.
Furosemide acts primarily on the thick ascending limb of the loop of Henle and inhibits the chloride transport in this site, which is the main mechanism of diuretic action of...
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An experimental study on renal damage induced by ionic contrast media in relation to iodine concentration

Sung DW, Yoon Y, Lim JH, Yang MH

Renal injury caused by iodinated contrast media has been widely known, but there has been few papers regardingthe pathological change. A series of rat kidneys after injection of iodinated contrast...
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Renal Handling of Ammonium and Acid Base Regulation

Kim HY

Renal ammonium metabolism is the primary component of net acid excretion and thereby is critical for acid - base homeostasis. Briefly, ammonium is produced from glutamine in the proximal tubule...
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A Case of Adult onset Bartter Syndrome with Nephrocalcinosis

Park MG, Lim TW, Oh HT, Song SU, Heo D, Rim H

Bartter syndrome is a renal tubular defect in electrolyte transport characterized by hypokalemia, metabolic alkalosis, hyperreninemia, hyperaldosteronism, normal blood pressure, and other clinical symptoms. As a clinical and genetical heterogeneous disorder,...
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Expression of Occludin in Porcine Renal Epithelial Cells

Lee SY, Han KH

  • KMID: 1472503
  • Korean J Anat.
  • 2009 Mar;42(1):11-17.
Occludin is a cell adhesion molecule that is abundantly expressed in the kidney. However, the expression pattern in various renal epithelial cells is not well established. The purpose of this...
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Two Cases of Gitelman's Syndrome Diagnosed by Renal Clearance Study

Ki JY, Kim HY, Im JM, Oh KS, Park YS, Kwon SG, Shin JS, Kim MS, Ji JH, Earm JH

  • KMID: 2079213
  • Korean J Nephrol.
  • 2001 Nov;20(6):1064-1069.
We have experienced two patients who had hypokalemic metabolic alkalosis as well as hypomagnesemia and hypocalciuria with elevated plasma renin activity. We have performed renal clearance study after water loading,...
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An Adult Case of Bartter Syndrome Type III Presenting with Proteinuria

Cha EJ, Hwang WM, Yun SR, Park MH

Bartter syndrome (BS) I-IV is a rare autosomal recessive disorder affecting salt reabsorption in the thick ascending limb of the loop of Henle. This report highlights clinicopathological findings and genetic...
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Expression of H(+)-ATPase in Inner Medullary Collecting Duct Cells of Aquaporin-3-Deficient Mice

Lee EJ, Kim WY, Han KH, Kim H, Kim J

  • KMID: 2092814
  • Korean J Anat.
  • 2003 Oct;36(5):443-455.
It has been reported that the decrease in urinary pH observed in AQP1 null mice with a urinary concentrating defect is due to upregulation of H(+)-ATPase in the IMCD. This...
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Autosomal dominant hypocalcemia with Bartter syndrome due to a novel activating mutation of calcium sensing receptor, Y829C

Choi KH, Shin CH, Yang SW, Cheong HI

The calcium sensing receptor (CaSR) plays an important role in calcium homeostasis. Activating mutations of CaSR cause autosomal dominant hypocalcemia by affecting parathyroid hormone secretion in parathyroid gland and calcium...
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Localization of E-cadherin Along the Nephron Segments in the Rat Kidney

Hwang IA, Ha H, Han KH

  • KMID: 2092913
  • Korean J Anat.
  • 2008 Mar;41(1):13-20.
E-cadherin is a cell adhesion molecule that is expressed abundantly in the kidney. However, the expression pattern in various renal epithelial cells is not well established. The purpose of this...
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Effects of Bilateral Ureteral Obstruction on Renal Aquaporin Expression

Jeong SJ, Chung SY, Nam KI, Lee SW, Park SS, Ahn KY

  • KMID: 2254387
  • Korean J Nephrol.
  • 2002 Jul;21(4):516-524.
BACKGROUND: Obstruction of urinary tract is common cause of renal disfunction. Recent discovery of aquaporin water channels expressed in the kidney and various organs has faciliated our understanding of water...
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Ultrastructural Changes of the Uriniferous Tubules after Ureteral Ligation in Rabbits

Yoon KH, Lim SK

  • KMID: 1911876
  • Korean J Urol.
  • 1986 Feb;27(1):15-31.
This study attempted to clarify the morphological changes of the uriniferous tubules in the postobstructed kidneys of rabbits by electron microscopy. A total of l3 rabbits weighing about 2.5 kg...
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Expression of ciliary neurotrophic factor and its receptor in experimental obstructive nephropathy

Lee BS, Choi JY, Cha JH

Ciliary neurotrophic factor (CNTF) is well known as a growth/survival factor of neuronal tissue. We investigated the expression of CNTF and its specific receptor alpha (CNTFRalpha) in a unilateral ureteral...
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Proper Use of Diuretics

Choi KH

Diuretics are among the most commonly used drugs. They primarily block active reabsorption of sodium at different sites in the nephron, thereby increasing urinary losses of NaCl and H2O. This...
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Alterations of Aquaporin-1, 2, 3 Protein Expression in Pregnant Rat Kidney

Cho HJ, Lee CB, Ahn KY

  • KMID: 2092953
  • Korean J Anat.
  • 2008 Dec;41(4):289-298.
The pregnancy causes the marked change in maternal renal hemodynamic and volume homeostasis. During pregnancy, renal sodium and water retention result in an expansion of extracellular fluid and plamsma volume....
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Alterations of Aquaporin mRNA and Protein Expression in Hypokalemic Rat Kidney

Kim DS, Lee CB, Bae CS, Kim BY, Park SS, Ahn KY

  • KMID: 1472505
  • Korean J Anat.
  • 2009 Mar;42(1):31-39.
There has been a general agreement that potassium depletion causes metabolic alkalosis and substantial morphological changes in kidney structure, and is associated with renal functional abnormalities, including a decrease in...
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Regulation of salt and volume transport along the nephron during acute systolic hypertension

McDonough , Zhang Y, Magyar CE, Mircheff A

  • KMID: 2071533
  • Korean J Physiol Pharmacol.
  • 1998 Oct;2(5):541-547.
DISCUSSION Acute regulation of sodium pump activity There is a burgeoning literature on mechanisms responsible for short term regulation of Na,K-ATPase activity (Aperia et al, 1996, 1994; Boron et al,...
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