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Lipid accumulation product is a predictor of nonalcoholic fatty liver disease in childhood obesity

Özcabı B, Demirhan S, Akyol M, Öztürkmen Akay H, Güven A

BACKGROUND: Lipid accumulation product (LAP) is associated with the presence and severity of nonalcoholic fatty liver disease (NAFLD) in adults. PURPOSE: Here we evaluated the ability of LAP to predict NAFLD...
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Association of serum levels of vascular endothelial growth factor and thrombospondin-1 to body mass index in polycystic ovary syndrome: a case-control study

Tahergorabi Z, Salmani F, Jonaidabad SH, Behdani B, Yazdi P, Zardast M, Moodi M

PURPOSE: Polycystic ovary syndrome (PCOS) is a gynecological endocrine disorder that is characterized by disturbances in ovarian blood flow and angiogenesis. The aim of this study was to determine the...
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The Correlation between the Ratio of Visceral Fat Area to Subcutaneous Fat Area on Computed Tomography and Lipid Accumulation Product as Indexes of Cardiovascular Risk

Kwon S, Han AL

BACKGROUND: Visceral obesity and cardiovascular disease are closely related. Research on relevant indexes of cardiovascular disease is particularly important. One of these indexes is lipid accumulation product (LAP). However, the...
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Effects of different exercise modalities on novel hepatic steatosis indices in overweight women with type 2 diabetes

Banitalebi E, Faramarzi , Nasiri S, Mardaniyan M, Rabiee V

BACKGROUND/AIMS: Fatty liver is a clinical and pathologic condition in individuals with type 2 diabetes (T2D). The purpose of this study is to examine the effects of different exercise modalities...
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Differences in Colistin-resistant Acinetobacter baumannii Clinical Isolates Between Patients With and Without Prior Colistin Treatment

Park YJ, Hong DJ, Yoon EJ, Kim D, Choi MH, Hong JS, Lee H, Yong D, Jeong SH

BACKGROUND: The increasing morbidity and mortality rates associated with Acinetobacter baumannii are due to the emergence of drug resistance and the limited treatment options. We compared characteristics of colistin-resistant Acinetobacter...
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Distinct Effects of Monophosphoryl Lipid A, Oligodeoxynucleotide CpG, and Combination Adjuvants on Modulating Innate and Adaptive Immune Responses to Influenza Vaccination

Ko EJ, Lee YT, Lee Y, Kim KH, Kang SM

Monophosphoryl lipid A (MPL) and oligodeoxynucleotide CpG are toll-like receptor (TLR) 4 and 9 agonist, respectively. Here, we investigated the effects of MPL, CpG, and combination adjuvants on stimulating in...
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Induction of Bronchial Tolerance After 1 Cycle of Monophosphoryl-A-Adjuvanted Specific Immunotherapy in Children With Grass Pollen Allergies

Rosewich M, Girod K, Zielen S, Schubert R, Schulze J

PURPOSE: Subcutaneous allergen-specific immunotherapy (SCIT) is a well-established and clinically effective method to treat allergic diseases, such as rhinitis and asthma. It remains unclear how soon after initiation of an...
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Lipid A as a Drug Target and Therapeutic Molecule

Joo SH

In this review, lipid A, from its discovery to recent findings, is presented as a drug target and therapeutic molecule. First, the biosynthetic pathway for lipid A, the Raetz pathway,...
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Helicobacter pylori Stool Antigen Levels and Serological Biomarkers of Gastric Inflammation are Associated with Cardio-Metabolic Risk Factors in Type 2 Diabetic Patients

Bahadoran , Mirmiran P, Zarif-yeaganeh M, Zojaji H, Azizi F

BACKGROUND: Helicobacter pylori infection and subsequent gastric inflammation have been proposed as risk factors for the development of insulin resistance and cardiovascular disease. In this study we assessed the possible...
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Effect of Intravenous Lipid Emulsion in the Patient with Acute Poisoning : A Systematic Review

Myung J, Ko DR, Kong T, Joo YS, You JS, Chung SP

  • KMID: 1846317
  • J Korean Soc Clin Toxicol.
  • 2015 Jun;13(1):1-10.
PURPOSE: The purpose of this study was to evaluate the usefulness of intravenous lipid emulsion as well as adverse events in acute poisoning patients. METHODS: Literature was accessed through PubMed, EMBASE,...
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Lipid Accumulation Product Is Associated with Insulin Resistance, Lipid Peroxidation, and Systemic Inflammation in Type 2 Diabetic Patients

Mirmiran P, Bahadoran , Azizi F

BACKGROUND: Lipid accumulation product (LAP) is a novel biomarker of central lipid accumulation related to risk of diabetes and cardiovascular disease. In this study, we assessed the association of LAP...
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Clinical and Biochemical Profiles according to Homeostasis Model Assessment-insulin Resistance (HOMA-IR) in Korean Women with Polycystic Ovary Syndrome

Lee DE, Park SY, Park SY, Lee SR, Chung HW, Jeong K

OBJECTIVES: The aim of this study was to investigate the clinical and biochemical profiles according to homeostasis model assessment of insulin resistance (HOMA-IR) in Korean polycystic ovary syndrome (PCOS) patients. METHODS:...
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Genetic Variants Associated with Calorie and Macronutrient Intake in a Genome-Wide Association Study

Baik I, Ahn Y, Lee SK, Kim S, Han BG, Shin C

There has been no genome-wide association study (GWAS) for macronutrient intake as a quantitative trait. To explore genetic loci associated with total calorie and macronutrient intake, genome-wide association data of...
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Vaccination with a Human Papillomavirus (HPV)-16/18 AS04-Adjuvanted Cervical Cancer Vaccine in Korean Girls Aged 10-14 Years

Kim YJ, Kim KT, Kim JH, Cha SD, Kim JW, Bae DS, Nam JH, Ahn WS, Choi HS

The human papillomavirus (HPV)-16/18 AS04-adjuvanted cervical cancer vaccine has been demonstrated to be highly efficacious and immunogenic with a favorable safety profile. This study assessed the immunogenicity and safety of...
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Discovery of Diagnostic Biomarkers for Legionnaires' Disease: Virulence Gene Expression Profiling of Legionella pneumophila serogroup 1 in A/J Mouse Model

Kim SM, Sim HS, Kim HS, Shim HK, Yoon YK, Kim JY, Park YS, Park DW, Sohn JW, Kim MJ

BACKGROUND: Legionella pneumophila is the causative agent of Legionnaires' disease, a severe form of pneumonia. After L. pneumophila is inhaled through contaminated aerosols, it is phagocytized by alveolar macrophages, multiplies...
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A Current Research Insight into Function and Development of Adjuvants

Sohn ES, Son E, Pyo S

In recent years, adjuvants have received much attention because of the development of purified subunit and synthetic vaccines which are poor immunogens and require adjuvants to evoke the immune response....
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In-vivo 1H MR Spectroscopy in Abscessess Induced in Rabbit Thighs: Evaluation of Treatment Effect

Goo JM, Chang KH, Lee KH, Han MH, Song IC

  • KMID: 1516297
  • J Korean Soc Magn Reson Med.
  • 2003 Jun;7(1):31-38.
PURPOSE: To analyze the serial changes of proton magnetic resonance (MR) spectra in the abscess and to determine the effect of the antibiotic treatment on the metabolite patterns. MATERIALS AND...
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Monophosphoryl lipid A (MPL) upregulates major histocompatibility complex (MHC) class I expression by increasing interferon-gamma (IFN-gamma)

Cho CH, Lee BK, Kwak SM, Kim JD

Tumor immunity is primarily mediated by cells as CD8+ cytotoxic T lymphocytes (CTL) recognize tumor antigen by MHC class I molecules. But most tumors are associated with a...
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Identification of a Lymphocyte Mitogenic Factor Produced by Actinobacillus actinomycetemcomitans

Seo SY, Jeong SJ, Yoo SH, Park SM, Jeong MH, Yee ST, Kim JM, Song JM, Jo WS, Lee SH

  • KMID: 2099300
  • J Korean Soc Microbiol.
  • 1998 Oct;33(5):521-535.
Actinobacillus actinomycetemcomitans, a gram-negative, capnophiTic bacterium, is associated with several human diseases including periodontal disease. Products of A. actinomycetemcomitans exert immunomodulatory effects on various lymphoid populations, some of which may...
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Regulation of mouse macrophage Fc receptor-mediated phagocytosis by interferon-r, lipid a and tumor necrosis factor

Kim JG

  • KMID: 1690586
  • Korean J Immunol.
  • 1993 May;15(1):45-51.
No abstract available.
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