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An Anti-Cancer Drug Candidate CYC116 Suppresses Type I Hypersensitive Immune Responses through the Inhibition of Fyn Kinase in Mast Cells

Park YH, Kim HW, Kim HS, Nam ST, Lee D, Lee MB, Min KY, Koo J, Kim SJ, Kim YM, Kim HS, Choi WS

Mast cells are the most prominent effector cells of Type 1 hypersensitivity immune responses. CYC116 [4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin-4-yl)phenyl] pyrimidin-2-amine] is under development to be used as an anti-cancer drug, but the inhibitory...
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Monocentric Derivative Y Chromosome with Duplication of the SRY Gene in an Azoospermic Male

Choi EY, Lee BY, Park JY, Lee YW, Oh AR, Lee SY, Kim SY, Han YJ, Lee MB, Ryu HM, Seo JT, Park SY

  • KMID: 2184483
  • J Genet Med.
  • 2010 Dec;7(2):160-164.
Structural abnormalities of the Y chromosome affect normal testicular differentiation and spermatogenesis. The present case showed a rare monocentric derivative Y chromosome with partial duplication of Yp including the SRY...
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Reduced Number of Endothelial Progenitor Colony-Forming Units in Patients with Preeclampsia

Kim SY, Park SY, Kim JW, Lee MB, Han YJ, Ahn HK, Choi JS, Han JY, Kim MY, Choi KH, Ryu HM

  • KMID: 2184479
  • J Genet Med.
  • 2010 Dec;7(2):138-144.
PURPOSE: Endothelial progenitor cells (EPCs), which mediates neovascularization of uterine endometrium may be involved in the neovascularization in the utero-placental circulation. Low numbers of endothelial progenitor colony-forming unit (CFU) in...
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Pregnancy Outcomes after Peri-conceptional Medication Exposure; 10 Years Experience: Study for Application of Reproductive Toxicity Information

Choi JS, Han JY, Ahn HK, Lee SW, Kim MH, Chung JH, Ryu HM, Kim MY, Yang JH, Choi KH, Han HW, Kim SH, Lee MB, Han YJ, Choi NM, Cho YK, Lee SY, Hong DS, Lim OR, Hong SC

  • KMID: 2072250
  • Korean J Perinatol.
  • 2010 Mar;21(1):48-58.
PURPOSE: In Korea, pregnancy termination is frequently reported among women who took medications for an acute or chronic disease during pregnancy, for fear of teratogenic risk. We have previously shown...
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Comparative analysis of pelvic inflammatory disease with and without Fitz-Hugh-Curtis syndrome

Yoon DK, Seo K, Lee MB, Lee KE, Jeon YE

  • KMID: 2273457
  • Korean J Obstet Gynecol.
  • 2008 Jun;51(6):659-664.
OBJECTIVE: This study was performed to compare the characteristics, hematologic findings, microbiologic results, and radiologic findings of the patients with Fitz-Hugh-Curtis Syndrome (FHCS) to those without perihepatitis. METHODS: From January 2003...
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Perinatal mortality at Yongdong Severance Hospital, 1998~2003

Cho SH, Oh JR, Yoon DK, Chae YH, Lee MB, Lee KE, Lee HS, Chun YE, Hwang JY, Kim JH, Lee BS, Seo K, Lee K

  • KMID: 2280761
  • Korean J Perinatol.
  • 2008 Mar;19(1):11-18.
OBJECTIVE: The aim of this study was to analyze the perinatal mortality rate (PMR) and to evaluate the risk factors of perinatal deaths such as birth weight, gestational age, maternal...
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A Case of Fetal Herpes Simplex Encephalitis Diagnosed Prenatally by Ultrasonography in the Third Trimester

Lee MB, Kim YR, Hwang HS, Park YW, Kim YH

  • KMID: 1512099
  • J Korean Soc Ultrasound Med.
  • 2007 Dec;26(4):207-210.
Almost all reported incidences of herpes simplex virus (HSV) infection in newborns result as a complication of rupture of the amniotic membranes or the delivery of the baby, but infection...
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Laparoscopic management of asymptomatic ovarian steroid cell tumors, not otherwise specified: A case report and literature review

Oh JR, Cho SH, Yoon DK, Cho HB, Lee KE, Lee MB, Hong SW, Lee BS

  • KMID: 2272833
  • Korean J Obstet Gynecol.
  • 2006 Apr;49(4):933-938.
The steroid cell tumor, not otherwise specified, constitutes only 0.1% of ovarian malignancies and was asymptomatic in 3.3-25% In Korea, three reported cases of steroid cell tumors were endocrinologically symptomatic...
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A Research on the Actual Condition of Antenatal Screening Application in Obstetric Clinics in Korea and Suggestions for Preparation of Antenatal Screening Guideline

Chae YH, Seo K, Yoon DK, Oh JR, Lee MB, Lee KE

  • KMID: 2272759
  • Korean J Obstet Gynecol.
  • 2006 Jan;49(1):55-63.
OBJECTIVE: Many countries including U.S. have established their own Antenatal Screening Guideline suitable for their actual state to help Obstetricians detect pregnancy-related problems in clinical conditions. However, even investigations on...
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A Case of Improved Refractory Uveitis in Behcet's Disease after Infliximab Therapy

Choi JW, Choi YJ, Ye YM, Kim SH, Nam DH, Park HS, Lee MB, Yoo HM, Suh CH

  • KMID: 2334831
  • J Korean Rheum Assoc.
  • 2005 Dec;12(4):320-323.
Behcet's disease is a multisystemic, chronic relapsing inflammatory disease characterized by vasculitides, mucocutaneous lesions, thrombophlebitis, arthritis. Among them, the ocular involvement is usual (50~70%) and the most serious morbidity is...
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Effects of 20% Aluminum Chloride Hexahydrate in Compensatory Hyperhidrosis

Lee SY, Lee SJ, Lee MB, Lee KR

  • KMID: 2289237
  • Korean J Thorac Cardiovasc Surg.
  • 2001 Jan;34(1):80-84.
BACKGROUND: Compensatory hyperhidrosis is the most common complication after thoracoscopic sympathetic operation in hyperhidrosis. It is not only decrease patient's satisfaction but also gives another burdens to the patients. Unfortunately...
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Tracheal Laceration Due to Thyroid Cartilage Fracture: One Case Report

Lee SY, Her K, Lee MB, Lee KR

  • KMID: 2062541
  • Korean J Thorac Cardiovasc Surg.
  • 2000 Nov;33(11):919-921.
A 50-year-old male visited the emergency room due to the cervical edema caused by a traffic accident. At the cervial CT, diagnosis was confirmed as extensive cervical subcutaneous emphysema secondary...
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A Experimental Study for the Effect of Sodium Carboxymethyl Cellulose on Prevention of Percardial Adhesion

Lee SY, Jeon CW, Lee MB, Lee KR, Koh ES, Uhm YI

  • KMID: 1987698
  • Korean J Thorac Cardiovasc Surg.
  • 2000 Jul;33(7):541-546.
BACKGROUND: Pericardial adhesion poses a major problem during re-operative cardiac surgery. The purpose of this study was to determine the effect of sodium carboxymethol cellulose on experimental pericardial adhesions. MATERIAL AND...
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Guidelines for the Adequate Initial Electric Stimuli in Bilateral ECT Using MECTA Device

Lee MB, Ahn JH, Lee C, Han OS, Kim CY

  • KMID: 1554199
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):138-142.
OBJECTIVE: In applying Electro-Convulsive Therapy(ECT) to patients, initial electric stimuli have been often determined without the adequate guidelines. This study was designed to determine adequate numerical value of parameters for...
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Metastatic Malignant Fibrous Histiocytoma in Lung: One Case Report

Lee SY, Lee MB, Lee KR, Ko ES

  • KMID: 2062226
  • Korean J Thorac Cardiovasc Surg.
  • 1999 Jul;32(7):671-674.
At OPD follow-up in December 1998, chest x-ray of a 42-year-old female showed a solit ary pulmonary nodule at a superior basal segment in the right lower lobe. After percut...
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Bilateral Large Thoracic Neuofibromas in Type I Neurofibromatosis

Park SQ, Chang JC, Doh JW, Kim BT, Shin WH, Choi SK, Byun BJ, Lee MB, Koh ES

  • KMID: 1955461
  • J Korean Neurosurg Soc.
  • 1999 Jan;28(1):92-96.
Type 1 Neurofibromatosis(von Recklinghausen's disease) characterized by cafe-au-lait spot and multiple skin nodules, may involve any part of the body. The incidence of multiple spinal neurofibromas is about 15% of...
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Central Vein Occlusion Secondary to Hemodialysis Catheterization in Chronic Renal Failure Patient: One Case Report

Lee SY, Lee JB, Lee MB, Yum W, Lee KR

  • KMID: 2062122
  • Korean J Thorac Cardiovasc Surg.
  • 1998 Jun;31(6):619-623.
A 51-year-old male with chronic renal failure had marked swelling and tenderness of the right arm. Venography revealed central vein occlusion involving stenosis of right proximal subclavian vein, right internal...
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An Epidemiologic Investigation of Typhoid Fever Outbreak in Pusan, 1996

Shin HR, Suh BS, Song JB, Lee DH, Lee MB, Park JH, Kim MS, Shin YH, Lee SW, Ohrr HC

  • KMID: 2304057
  • Korean J Epidemiol.
  • 1997 Dec;19(2):122-130.
An epidemiologic investigation was carried out to identify the source of infection of typhoid fever outbreak, which was occurred in Nam-Gu, Pusan city from April 20 to June 28, 1996....
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Effect of Recovery of Pulmonary Function in Hypothermic Lung Preservation

Lee MB, Kim WJ, Kang CH, Lee KR

  • KMID: 2061888
  • Korean J Thorac Cardiovasc Surg.
  • 1997 Mar;30(3):253-262.
Hypothermia during lung preservation decreases metabolic processes. After the rabbit lung was flushed with modified Euro-Collins solution, heart-lung block was harvested and the left lung was assessed after ligation of...
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