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Oncological impact of vascular invasion in colon cancer might differ depending on tumor sidedness

Abdelgawaad Shalkamy MS, Bae JH, Lee CS, Han SR, Kim JH, Kye BH, Lee IK, Lee YS

Purpose: Vascular invasion is a well-known independent prognostic factor in colon cancer and tumor sidedness is also being considered a prognostic factor. The aim of this study was to compare...
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Development of the Korean Version of the Gastrointestinal Quality of Life Index Questionnaire

Yang IJ, Oh HK, Lee J, Suh JW, Ahn Hm, Park H, Sim HH, Cho YB, Lee IK, Ryoo S, Lee DW, Kim DW, Kang SB

Purpose: To establish a standardized quality of life measurement that allows global cross-study comparisons, we translated the Gastrointestinal Quality of Life Index (GIQLI) into Korean and linguistically validated the Korean...
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Implementation and improvement of Enhanced Recovery After Surgery protocols for colorectal cancer surgery

Choi BY, Bae JH, Lee CS, Han SR, Lee YS, Lee IK

Purpose: Enhanced Recovery After Surgery (ERAS) reduces postoperative complications and shortens hospital stays. We aimed to describe the implementation and improvement of ERAS protocols in our institution through a multidisciplinary...
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Short- and long-term outcomes of local excision with adjuvant radiotherapy in high-risk T1 rectal cancer patients

Al-Sawat A, Bae JH, Kim HH, Lee CS, Han SR, Lee YS, Cho H, Jang HS, Lee IK

Purpose: The standard of care for early rectal cancer is radical surgery; however, it carries high postoperative morbidity. This study aimed to assess the short-term and oncological outcomes of local...
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Chemical Constituents of the Culture Broth ofPanus rudis

Song JG, Ha LS, Ki DW, Choi DC, Lee IK, Yun BS

In our ongoing search for new secondary metabolites from fungal strains, one novel compound (1) and nine known compounds (2-10) were isolated from the EtOAc-soluble layer of the culture broth...
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Predictive factors of high comprehensive complication index in colorectal cancer patients using Enhanced Recovery After Surgery protocol: role as a safety net in early discharge

Jin HY, Hong I, Bae JH, Lee CS, Han SR, Lee YS, Lee IK

Purpose: This study was performed to evaluate complications using comprehensive complication index (CCI) in colorectal cancer patients with implementation of the Enhanced Recovery After Surgery (ERAS) protocol, and to investigate...
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The additional analgesic effects of transverse abdominis plane block in patients receiving low-dose intrathecal morphine for minimally invasive colorectal surgery: a randomized, single-blinded study

Han SR, Lee CS, Bae JH, Lee HJ, Yoon MR, Lee DS, Lee YS, Al-Sawat A, Shim JW, Hong SH, Lee IK

Purpose: Intrathecal analgesia (ITA) and transverse abdominis plane block (TAPB) are effective pain control methods in abdominal surgery. However, there is still no gold standard for postoperative pain control in...
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Which prognostic factors are important for long-term outcomes in symptomatic obstructive colon cancer? A multi-institutional retrospective cohort study

Kim CH, Bae JH, Lee CS, Han SR, Lee IK, Lee D, Kang WK, Kim JH, Kye BH, Cho HM, Oh ST, Lee SC, Lee YS

Purpose: The prognostic factors in obstructive colon cancer have not been clearly identified. We aimed to identify the prognostic factor to establish optimal treatment strategy in obstructive colon cancer. Methods: Patients...
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Survey on Public Awareness of Neurology in Korea

Park J, Kim H, Park JH, Shin WC, Lee IK, Lim JS, Yang J, Hong SB, Park KH

Background: Neurology in Korea is a field of clinical practice and research that has been developing for over 30 years, but due to its relatively short history, public awareness is...
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Consoramides A–C, New Zwitterionic Alkaloids from the Fungus Irpex consors

Kim JY, Ki DW, Lee YJ, Ha LS, Woo EE, Lee IK, Yun BS

In our ongoing search for new secondary metabolites from fungi, a basidiomycete fungus Irpex consors was selected for mycochemical investigation, and three new zwitterionic alkaloids (1-3) and five known compounds...
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Comparing the Postoperative Outcomes of Single-Incision Laparoscopic Appendectomy and Three Port Appendectomy With Enhanced Recovery After Surgery Protocol for Acute Appendicitis: A Propensity Score Matching Analysis

Kim WJ, Jin HY, Lee H, Bae JH, Koh W, Mun JY, Kim HJ, Lee IK, Lee YS, Lee CS

Purpose: The objective of this study was to compare the perioperative outcomes between single-incision laparoscopic appendectomy (SILA) and 3-port conventional laparoscopic appendectomy (CLA) in enhanced recovery after surgery (ERAS) protocol. Methods:...
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Impact of urgently initiated tele-prescription due to COVID-19 on glycemic control in patients with type 2 diabetes

Park SD, Kim Ny, Jeon JH, Kim JG, Lee IK, Park KG, Choi YK

Background/Aims: Coronavirus disease 2019 (COVID-19) is a global pandemic that had affected more than 13,000 people in South Korea by July 2020. To prevent spread of COVID-19, tele-prescription was permitted...
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Surtuin 1 as a potential prognostic biomarker in very elderly patients with colorectal cancer

Lee GJ, Jung YH, Kim TJ, Chong Y, Jeong SW, Lee IK, Woo IS

Background/Aims: Colorectal cancer (CRC) rate increases with aging. Aging-related proteins, such as sirtuins (SIRTs) may be a potential therapeutic target in the elderly patients with CRC. The clinical implications of...
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The usefulness of transanal tube for reducing anastomotic leak in mid rectal cancer: compared to diverting stoma

Cho SH, Lee IK, Lee YS, Kim MK

Purpose: Diverting stoma (DS) and transanal tube (TAT) are the 2 main procedures for reducing anastomotic leak (AL) in rectal cancer surgery. However, few studies have compared the protective effect...
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Chemical Composition of Artemisia argyi Extract (RW0117) and Protective Effects against Gastric Lesions in vivo

Lee JW, Park SH, Jegal CM, Choi KY, Jung HY, Choi JA, Lee CK, Kim HK, Lee JS, Lee IK

In this study, we investigated the chemical profile and effects of RW0117 (Artemisia argyi 65 .5 % ethanol extract) on gastric lesions in rats. We optimized and validated a method...
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The Effect of Combined Growth Hormone and a Gonadotropin-Releasing Hormone Agonist Therapy on Height in Korean 3-M Syndrome Siblings

Lee IK, Lim HH, Kim YM

3-M syndrome is a rare autosomal recessive growth disorder characterized by severe growth retardation, low birth weight, characteristic facial features, and skeletal anomalies, for which three causative genes (CUL7, OBSL1,...
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Surgical skin adhesive bond is safe and feasible wound closure method to reduce surgical site infection following minimally invasive colorectal cancer surgery

Lee CS, Han SR, Kye BH, Bae JH, Koh W, Lee IK, Lee DS, Lee YS

Purpose: Minimally invasive colorectal surgery had reduced the rate of surgical site infection. The use of surgical skin adhesive bond (2-octyl cyanoacrylate) for wound closure reduces postoperative pain and provides...
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Influence of the Enhanced Recovery After Surgery Protocol on Postoperative Inflammation and Short-term Postoperative Surgical Outcomes After Colorectal Cancer Surgery

Jallounv HE, Lee IK, Kim MK, Sung NY, Turkistani SAA, Park SM, Won DY, Hong SH, Kye BH, Lee YS, Jeon HM

Purpose: Many studies have shown that the enhanced recovery after surgery (ERAS) protocols improve postoperative surgical outcomes. The purpose of this study was to observe the effects on postoperative inflammatory...
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Robotic Lateral Pelvic Lymph Node Dissection: Description of A Technique

Alturkistani SA, Alghanem AM, Lee IK

Different surgical approaches have been reported in the management of lateral pelvic lymph node dissection (LPND) including open, laparoscopic and robotic. Since the introduction of Da Vinci robotic system in...
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Evogliptin, a Dipeptidyl Peptidase-4 Inhibitor, Attenuates Renal Fibrosis Caused by Unilateral Ureteral Obstruction in Mice

Kim MJ, Kim NY, Jung YA, Lee S, Jung GS, Kim JG, Lee IK, Lee S, Choi YK, Park KG

Renal fibrosis is considered to be the final common outcome of chronic kidney disease. Dipeptidyl peptidase-4 (DPP-4) inhibitors have demonstrated protective effects against diabetic kidney disease. However, the anti-fibrotic effect...
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