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Distinct Repopulation Activity in Hu-Mice between CBand LPB-CD34 Cells by Enrichment of Transcription Factors

Han AR, Lee JE, Lee MJ, Ko SY, Shin HS, Lee JY, Lee DR

Background and Objectives: Human CD34+hematopoietic stem cells can reconstitute the human hematopoietic system when transplanted into immunocompromised mice after irradiation. Human leukapheresis peripheral blood (LPB)-and cord blood (CB)-derived CD34+ cells...
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Trajectories of Body Mass Index and Their Associations with Mortality among Older Adults in Korea: Analysis of the Korean Longitudinal Study of Aging

Kong JW, Park T, Lee DR, Lee J

Background: Weight change is a known risk factor for mortality. Previous Korean studies only considered mortality consequences of weight change between two time points over relatively short periods. This study...
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Anti-fracture Efficacy of Monthly Risedronate Compared with That of Weekly Risedronate in Postmenopausal Korean Women with Osteoporosis: A Nationwide Cohort Study

Cho YH, Bae KH, Lee DR, Lee J

Background: Intermittent dosing regimens for oral risedronate (once-monthly and once-weekly) were developed for patient convenience. While several studies have reported the anti-fracture efficacy of weekly dosing, few have assessed monthly...
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Fear of Falling and Mortality among Older Adults in Korea: Analysis of the Korean Longitudinal Study of Aging

Lee A, Lee J, Lee G, Lee DR

Background: The fear of falling (FOF) has been reported in a high percentage of elderly people. An excessive FOF is a major concern among the elderly because it can lead...
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Analysis of the characteristics of unplanned admission to the intensive care unit after general surgery

Kim J, Kim YD, Lee DR, Kim KM, Lee WY, Lee S

BACKGROUND: Unplanned intensive care unit admission (UIA) is associated with perioperative morbidity and mortality, and can be used as a surrogate marker for patient safety. This study aimed to compare...
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A case of Castleman disease that improved after kidney transplantation

Lee HR, An JM, Lee DR, Choi HW, Oh JS, Kim JK

This is a case of a 56-year-old man with Castleman disease (CD) who improved after kidney transplantation (KTP). CD is an uncommon lymphoproliferative disorder that was found incidentally on biopsy...
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The Relationship between Handgrip Strength and Cognitive Function in Elderly Koreans over 8 Years: A Prospective Population-Based Study Using Korean Longitudinal Study of Ageing

Kim KH, Park SK, Lee DR, Lee J

BACKGROUND: Decreased physical performance, such as weakened handgrip strength and cognitive decline, is associated with disability and premature death in old age. We investigated the association between handgrip strength and...
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The Role of Beta-Tricalcium Phosphate-Hydrogel Scaffold and Mesenchymal Stem Cells on Neogenic Bone Formation

Lee DR, Kang YK

PURPOSE: The purpose of this paper was to determine the ability of a mixture consisting of mesenchymal stem cells, beta-tricalcium phosphate β-TCP), and hydrogel, to support cells and form new...
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Effect of Fenofibrate Medication on Renal Function

Kim S, Ko K, Park S, Lee DR, Lee J

BACKGROUND: Fibrates are widely used to treat hypertriglyceridemia, a risk factor for arteriosclerosis, but these compounds have been associated with renal dysfunction. This study aimed to investigate the effects of...
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Transcriptional regulatory networks underlying the reprogramming of spermatogonial stem cells to multipotent stem cells

Jeong HS, Bhin J, Kim HJ, Hwang D, Lee DR, Kim KS

Spermatogonial stem cells (SSCs) are germline stem cells located along the basement membrane of seminiferous tubules in testes. Recently, SSCs were shown to be reprogrammed into multipotent SSCs (mSSCs). However,...
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Knowledge, Current Status, and Barriers toward Healthcare Worker Vaccination among Family Medicine Resident Participants in a Web-Based Survey in Korea

Ko K, Kim S, Kim SH, Son KY, Lee J, Lee DR

BACKGROUND: We investigated the knowledge, status, and barriers toward healthcare workers receiving vaccinations among Korean family medicine residents. To date, a systematic study has not been conducted among medical practitioners...
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Clinical outcomes of single versus double blastocyst transfer in fresh and vitrified-warmed cycles

Eum JH, Park JK, Kim SY, Paek SK, Seok HH, Chang EM, Lee DR, Lee WS

OBJECTIVE: Assisted reproductive technology has been associated with an increase in multiple pregnancies. The most effective strategy for reducing multiple pregnancies is single embryo transfer. Beginning in October 2015, the...
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Application of serum anti-Müllerian hormone levels in selecting patients with polycystic ovary syndrome for in vitro maturation treatment

Seok HH, Song H, Lyu SW, Kim YS, Lee DR, Lee WS, Yoon TK

OBJECTIVE: The purpose of this study was to identify useful clinical factors for the identification of patients with polycystic ovary syndrome (PCOS) who would benefit from in vitro maturation (IVM)...
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De Novo AL Amyloidosis in a Renal Allograft

Hwang JY, Lee DR, An JM, Kim SJ, Kim DK, Park MG, Park SH

Amyloidosis is characterized by the extracellular deposition of amyloid in various tissues and organs, particularly the kidney and heart. The estimated incidence of systemic amyloidosis is at least 8 per...
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Association Between Exposure to Environmental Tobacco Smoke at the Workplace and Risk for Developing a Colorectal Adenoma: A Cross-Sectional Study

Lee SH, Hong JY, Lee JU, Lee DR

PURPOSE: A colorectal adenoma (CRA) is a well-defined precursor to colorectal cancer (CRC). Additionally, smoking is a potent risk factor for developing a CRA, as well as CRC. However, the...
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The Change of Surface Temperature in Healing Process of Wound and Burn in Porcine Model

Kim SH, Lee DR, Song KJ, Lee SJ, Shin MH, Oh SB, Kwon IS, Hwang TS

PURPOSE: The goal of wound managements are to prevent further tissue injury during dressing changes, and absorb the excessive exudates, provide moist condition, reduce the infection. But the usual dressing...
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Preventable Trauma Death Rate in Daegu, South Korea

Moon S, Lee SH, Ryoo HW, Kim JK, Ahn JY, Kim SJ, Jeon JC, Lee KW, Sung AJ, Kim YJ, Lee DR, Do BS, Park SR, Lee JS

PURPOSE: This study was performed to investigate the preventable death rate (PDR) in Daegu, South Korea, and to assess both its affecting- and preventable-factors to improve the treatment of regional...
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Cutaneous and Systemic Plasmacytosis Associated with Renal Amyloidosis

Lee TG, Jeong WS, Moon SH, Hwangbo H, Lee SK, Lee DR, Kwon TG

Cutaneous and systemic plasmacytosis (CSP) is a rare disorder of unknown etiology characterized by cutaneous polyclonal plasma cell infiltrates associated with various extracutaneous involvement and polyclonal hypergammaglobulinemia. Here, we report...
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The effect of dexmedetomidine sedation on patient and surgeon satisfaction during retinal surgery under sub-tenon's anesthesia: a randomized controlled trial

Yoo JH, Kim SI, Cho A, Lee SJ, Sun HJ, Cho HB, Lee DR

BACKGROUND: The purpose of this study was to evaluate the effect of intraoperative dexmedetomidine sedation on patient's and surgeon's satisfaction during retinal surgery under sub-tenon's anesthesia. METHODS: Forty-four patients scheduled for...
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Clinical characteristics of children and adolescents with croup and epiglottitis who visited 146 Emergency Departments in Korea

Lee DR, Lee CH, Won YK, Suh DI, Roh EJ, Lee MH, Chung EH

PURPOSE: Croup is a common pediatric respiratory illness with symptoms of varying severity. Moreover, epiglottitis is a rare disease that can rapidly progress to life-threatening airway obstruction. Although the clinical...
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