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Effects of Novel Probiotics in a Murine Model of Irritable Bowel Syndrome

Chung HG, Min YW, Lee C, Hong SN, Won JY, Jang JA, Kim CH, Chang DK

BACKGROUND/AIMS: Dysbiosis is an important factor in the pathogenesis of irritable bowel syndrome (IBS). Several studies have reported promising results using probiotics for the treatment of IBS. This study evaluated...
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Minocycline and Its Impact on Microbial Dysbiosis in the Skin and Gastrointestinal Tract of Acne Patients

Thompson K, Rainer BM, Antonescu , Florea L, Mongodin E, Kang S, Chien AL

BACKGROUND: Associations between acne and gastrointestinal comorbidities suggest that microbial dysbiosis and intestinal permeability may promote inflammatory acne, a condition often managed with oral antibiotics. OBJECTIVE: We performed a case-control study...
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Risk and Protective Factors for Gastrointestinal Symptoms associated with Antibiotic Treatment in Children: A Population Study

Baù M, Moretti A, Bertoni E, Vazzoler V, Luini C, Agosti M, Salvatore

PURPOSE: Gastrointestinal symptoms are often related to antibiotic treatment. Their incidence, risk and protective conditions in children are not well defined and represent the aims of this study. METHODS: We prospectively...
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Sex-related Alterations of Gut Microbiota in the C57BL/6 Mouse Model of Inflammatory Bowel Disease

Son HJ, Kim N, Song CH, Nam RH, Choi SI, Kim JS, Lee DH

BACKGROUND: Gut microbiota is closely associated with development and exacerbation of inflammatory bowel diseases (IBD). The aim of this study was to investigate differences in gut microbiota depending on sex...
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Assessment of bacterial contamination of toothbrushes using Illumina MiSeq

Lee SY, Lee SY

Toothbrushes are commonly used to remove dental plaque, and the presence of bacteria on toothbrushes has been previously reported. Toothbrushes are contaminated by many bacteria after brushing, and contaminated toothbrushes...
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Analysis of Correlation among Oral Environment, Oral Myofunction, and Oral Microorganisms

Kim SH

BACKGROUND: Factors affecting oral function include tooth number, oral muscle strength, and oral diseases. This study aimed to investigate the relationship among oral environment, muscle, and microbiology. METHODS: Fifty-six elderly individuals...
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The role of Lactobacillus reuteri DSM 17938 for the absorption of iron preparations in children with iron deficiency anemia

Manoppo J, Tasiringan H, Wahani A, Umboh A, Mantik M

PURPOSE: To determine whether Lactobacillus reuteri DSM 17938 plays a role in absorption of iron preparations given to children with iron deficiency anemia (IDA). METHODS: We performed a quasi-experimental study involving...
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Extracellular Vesicles Derived from Lactobacillus plantarum Increase BDNF Expression in Cultured Hippocampal Neurons and Produce Antidepressant-like Effects in Mice

Choi J, Kim YK, Han PL

Gut microbiota play a role in regulating mental disorders, but the mechanism by which gut microbiota regulate brain function remains unclear. Gram negative and positive gut bacteria release membrane-derived extracellular...
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Dietary effect of Lactobacillus plantarum CJLP55 isolated from kimchi on skin pH and its related biomarker levels in adult subjects

Han S, Shin J, Lim S, Ahn HY, Kim B, Cho Y

PURPOSE: The skin pH is maintained by epidermal lactate, free fatty acids (FFAs), and free amino acids (FAAs). As a significant determinant of skin health, the skin pH is increased...
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Additive effect of Lactobacillus acidophilus L-92 on children with atopic dermatitis concomitant with food allergy

Nakata J, Hirota T, Umemura H, Nakagawa T, Kando N, Futamura M, Nakamura Y, Ito K

BACKGROUND: Atopic dermatitis (AD) in infants is often related to food allergies (FA). The beneficial effects of lactic acid bacteria towards allergic diseases have been reported, but there are few...
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Assessment of bacterial contamination of mobile phones of dentists and dental hygienists by Illumina MiSeq

Lee SY, Lee SY

In a clinical environment, medical staffs often use their mobile phones with their bare hands, thereby possibly exposing them to bacteria contamination. Cross-contamination could occur, where bacteria may be transferred...
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Clinical Characteristics of Infantile Colic

Nam SK, Park S, Lee J, Jun YH

PURPOSE: To diagnose infantile colic from parent questionnaires, as well as investigating the risk factors and clinical course of infantile colic. METHODS: We retrospectively reviewed the medical records of 462 infants,...
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Endodontic biofilms: contemporary and future treatment options

Yoo YJ, Perinpanayagam H, Oh S, Kim AR, Han SH, Kum KY

Apical periodontitis is a biofilm-mediated infection. The biofilm protects bacteria from host defenses and increase their resistance to intracanal disinfecting protocols. Understanding the virulence of these endodontic microbiota within biofilm...
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High-quality draft genome and characterization of commercially potent probiotic Lactobacillus strains

Sulthana A, Lakshmi SG, Madempudi

Lactobacillus acidophilus UBLA-34, L. paracasei UBLPC-35, L. plantarum UBLP-40, and L. reuteri UBLRU-87 were isolated from different varieties of fermented foods. To determine the probiotic safety at the strain level,...
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Lactobacillus pentosus Modulates Immune Response by Inducing IL-10 Producing Tr1 Cells

Kim JE, Sharma A, Sharma G, Lee SY, Shin HS, Rudra D, Im SH

Several gut commensals have been shown to modulate host immune response. Recently, many food derived microbes have also been reported to affect the immune system. However, a mechanism to identify...
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Characteristics of Vegetable Juice Fermented with Lactobacillus plantarum MKHA15 and Leuconostoc mesenteroids MKSR

Jang H, Kim M

The objective of this study was to develop fermented vegetable juices that possess antidiabetic and antioxidant activities. Lactobacillus plantarum MKHA15 (MKHA15) and Leuconostoc mesenteroides MKSR (MKSR) were applied to ferment...
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Lactobacillus reuteri DSM 17938 Improves Feeding Intolerance in Preterm Infants

Kaban RK, Wardhana , Hegar B, Rohsiswatmo R, Handryastuti S, Amelia N, Muktiarti , Indrio F, Vandenplas Y

PURPOSE: Feeding tolerance is extremely important in preterm infants. This study aimed to evaluate whether preterm infants receiving Lactobacillus reuteri DSM 17938 would develop fewer symptoms of feeding intolerance. Secondary...
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A phase 1/2a, dose-escalation, safety and preliminary efficacy study of oral therapeutic vaccine in subjects with cervical intraepithelial neoplasia 3

Park YC, Ouh YT, Sung MH, Park HG, Kim TJ, Cho CH, Park JS, Lee JK

OBJECTIVE: Persistent infection of HPV increases the chance of carcinoma in situ of cervix through stages of cervical intraepithelial neoplasia (CIN) 1, 2, and 3, and finally progresses into cervical...
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Differential Effects of Lactobacillus casei Strain Shirota on Patients With Constipation Regarding Stool Consistency in China

Chen S, Ou Y, Zhao L, Li Y, Qiao Z, Hao Y, Ren F

  • KMID: 2433508
  • J Neurogastroenterol Motil.
  • 2019 Jan;25(1):148-158.
  • doi: 10.5056/jnm17085
BACKGROUND/AIMS: Probiotics are expected to confer benefits on patients with constipation, but how probiotics act on constipated patients with variable stool consistencies remains unclear. We investigated the effect of Lactobacillus...
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Lactobacillus plantarum-derived Extracellular Vesicles Protect Atopic Dermatitis Induced by Staphylococcus aureus-derived Extracellular Vesicles

Kim MH, Choi SJ, Choi HI, Choi JP, Park HK, Kim EK, Kim MJ, Moon BS, Min TK, Rho M, Cho YJ, Yang S, Kim YK, Kim YY, Pyun BY

PURPOSE: The microbial environment is an important factor that contributes to the pathogenesis of atopic dermatitis (AD). Recently, it was revealed that not only bacteria itself but also extracellular vesicles...
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