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A Case of Donor Cell Leukemia after Allogenic Peripheral Blood Stem Cell Transplantation for Acute Promyelocytic Leukemia with PML-RARA

Shin WY, Bang HI, Kim J, Kim KH, Won JH, Park R

  • Lab Med Online.
  • 2020 Jan;10(1):88-91.
  • doi: 10.3343/lmo.2020.10.1.88
Donor cell leukemia (DCL), a rare but fatal complication arising from allogenic stem cell transplantation, is a complex disease associated with multiple pathophysiological processes. Specific diagnosis of DCL distinct from...
Anti-PP₁P(k) (Tj(a)) Antibody in a Korean Female Patient with p Phenotype Confirmed by Genotyping

Kim B, Choi SJ, Cho D, Kim S, Kim HO

  • Lab Med Online.
  • 2020 Jan;10(1):84-87.
  • doi: 10.3343/lmo.2020.10.1.84
In this study, we report a case of anti-PP₁P(k) (Tj(a)) alloantibody with p phenotype detected and confirmed in a 20-year-old Korean woman diagnosed with anemia during long-term rehabilitation treatment due...
Clinical Impact of Myeloid-Derived Suppressor Cells, Lymphocyte Subsets, and Neutrophil-to-Lymphocyte Ratio in Patients with Colorectal Cancer

Kang MG, Kim CH, Kim SH, Shin JH, Kim HR, Shin MG

  • Lab Med Online.
  • 2020 Jan;10(1):75-83.
  • doi: 10.3343/lmo.2020.10.1.75
BACKGROUND: Preoperative myeloid-derived suppressor cells (MDSCs), neutrophil-to-lymphocyte ratio (NLR), and lymphocyte subsets have been reported to be associated with the clinical outcomes in colorectal cancer (CRC). However, studies on the...
Performances of CYFRA 21-1, Carcinoembryonic Antigen and Their Combination for Lung Cancer Diagnosis

Kim JJ, Ahn HJ, Park Y

  • Lab Med Online.
  • 2020 Jan;10(1):66-74.
  • doi: 10.3343/lmo.2020.10.1.66
BACKGROUND: The aim of this study was to compare the efficiency of cytokeratin 19 fragment (CYFRA 21-1) and carcinoembryonic antigen (CEA) for the diagnosis of lung cancer and to establish...
Different Quantitative Interferon-γ Response in Active Tuberculosis of Various Primary Infection Sites

Lee H, Kim KH

  • Lab Med Online.
  • 2020 Jan;10(1):58-65.
  • doi: 10.3343/lmo.2020.10.1.58
BACKGROUND: The quantitative interferon (IFN)-γ response in the IFN-γ release assay (IGRA) has been investigated to predict progression from Mycobacterium tuberculosis infection to active tuberculosis (TB). However, the significance of...
Performance Evaluation of MEDITAPE UC-11A Strip Test in Estimating the Urine Albumin-to-Creatinine Ratio and Urine Protein-to-Creatinine Ratio

Yu S, Song SA, Jun KR, Lee JN

  • Lab Med Online.
  • 2020 Jan;10(1):52-57.
  • doi: 10.3343/lmo.2020.10.1.52
BACKGROUND: Proteinuria, including albuminuria, is a primary or major clinical sign of kidney disease. The urine albumin-to-creatinine ratio (UACR) and urine protein-to-creatinine ratio (UPCR) are used to screen patients with...
Evaluation of Analytical Performance of an Automated Glycated Hemoglobin Analyzer, HLC-723 G11

Chung YN, Yun SG, Cho Y

  • Lab Med Online.
  • 2020 Jan;10(1):46-51.
  • doi: 10.3343/lmo.2020.10.1.46
BACKGROUND: Glycated hemoglobin (HbA(1c)) is a key biomarker for the monitoring of glycemic balance in patients with diabetes. The aim of this study was to evaluate the performance of a...
Comparison of Serum Creatinine Measurements among Roche Modular D, Cobas 8000 c702, and Beckman Coulter AU5800, by Jaffe and Enzymatic Methods

Oh J, Park HD

  • Lab Med Online.
  • 2020 Jan;10(1):39-45.
  • doi: 10.3343/lmo.2020.10.1.39
BACKGROUND: Creatinine (Cr) is a representative biomarker reflecting renal function. In this study, we compared serum Cr levels using Roche Modular D (Roche Diagnostics, Germany), Roche Cobas 8000 c702 (Roche...
Performance Evaluation and Clinical Usefulness of α-fetoprotein Test Measured on Sysmex HISCL-5000

Jung J, Kang ES, Park HD

  • Lab Med Online.
  • 2020 Jan;10(1):33-38.
  • doi: 10.3343/lmo.2020.10.1.33
BACKGROUND: Serum α-fetoprotein (AFP) test is useful for the diagnosis of hepatocellular carcinoma (HCC) and monitoring its recurrence after treatment. In Korea, patients with a higher risk of HCC are...
Performance Evaluation of the CS-5100 Coagulation Analyzer for Special Coagulation Parameters

Kim B, Jang S, Lee YJ, Park N, Cho YU, Park CJ

  • Lab Med Online.
  • 2020 Jan;10(1):25-32.
  • doi: 10.3343/lmo.2020.10.1.25
BACKGROUND: The CS-5100 high-throughput automated coagulometer (Sysmex, Japan) can perform general and special coagulation assays. We evaluated the performance of the CS-5100 coagulometer to measure fibrinogen degradation product (FDP), plasma...
Revision of Laboratory Testing Guidelines for Initial Diagnosis of Hematologic Neoplasms

Kim IS, Lee JY, Kong SY, Lee ST, Huh J, Nam MH, Kim M, Cho YU, Huh HJ, Song J, Park H

  • Lab Med Online.
  • 2020 Jan;10(1):10-24.
  • doi: 10.3343/lmo.2020.10.1.10
The standardization committee of the Korean Society for Laboratory Hematology revised laboratory testing guidelines in order that hematologic neoplasms could be diagnosed according to the revised 4th edition of WHO...
Recommendations for the Use of Liquid Chromatography-Mass Spectrometry in the Clinical Laboratory: Part I. Implementation and Management

Lee K, Moon SY, Kim S, Choi HJ, Lee SG, Park HD, Lee SY, Song SH, Clinical Mass Spectrometry Research Committee of the Korean Society of Clinical Chemistry

  • Lab Med Online.
  • 2020 Jan;10(1):1-9.
  • doi: 10.3343/lmo.2020.10.1.1
Many types of assays involving mass spectrometry have been developed and applied in clinics. However, mass spectrometry has not been widely implemented yet relative to other measurement methods, including biochemical...

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