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7 results

A Case of Bone Marrow Necrosis in B-Acute Lymphoblastic Leukemia with Philadelphia Chromosome at Presentation

Jeong IH, An GD, Lim HH, Woo KS, Kim KH, Kim JM, Lee JH, Han JY

  • Lab Med Online.
  • 2018 Oct;8(4):171-176.
  • doi: 10.3343/lmo.2018.8.4.171
Bone marrow necrosis (BMN) is a pathologic state which is derived from various disease entities. Most commonly, it is accompanied by hematologic malignancies such as acute leukemia. The patients with...
Primary Myelofibrosis with MPL S505N Mutation: The First Case Reported in Korea

Kim UJ, Lee HJ, Choi IS, Kang SH, Jang SJ, Moon DS, Park G

  • Lab Med Online.
  • 2018 Oct;8(4):167-170.
  • doi: 10.3343/lmo.2018.8.4.167
MPL mutation is an important molecular marker in myeloproliferative neoplasms (MPN). Although MPL W515 is a hot spot for missense mutations in MPN, MPL S505 mutations have been reported in...
Germline Variants in MLH1, MSH2, and MSH6 in Korean Patients with Lynch Syndrome

Park KJ, Chang DK, Kim HC, Kim JW

  • Lab Med Online.
  • 2018 Oct;8(4):156-166.
  • doi: 10.3343/lmo.2018.8.4.156
BACKGROUND: The phenotypic and genetic spectrum of Lynch syndrome (LS) seems to differ according to ethnicity. The aim of this study was to investigate the clinical, pathological, and genetic features...
Genetic Screening for Chromosomal Abnormalities and Y Chromosome Microdeletions in 846 Infertile Korean Men

Han SH, Bak CW, Cho H, Ban GW, Kang JS, Lim HS, Lee KR, Hwang SY

  • Lab Med Online.
  • 2018 Oct;8(4):148-155.
  • doi: 10.3343/lmo.2018.8.4.148
BACKGROUND: Chromosomal abnormalities are confirmed as one of the frequent causes of male infertility. The microdeletion of the azoospermia factor (AZF) region in the Y chromosome was discovered as another...
Clinical Usefulness of ImmuneCheckâ„¢ IgG for Rapid Semiquantitation of Total IgG

Choi J, Lee SC, Park KH, Yoon H, Kim HS, Park JW

  • Lab Med Online.
  • 2018 Oct;8(4):140-147.
  • doi: 10.3343/lmo.2018.8.4.140
BACKGROUND: Conventional IgG assays require costly equipment and skilled experts. Semiquantitative measurement of total IgG using point-of-care testing devices may be the solution for these limitations. This study evaluated the...
Performance Evaluation of the Point-of-Care Cardiac Troponin T Assay

Kim YH, Jeong TD, Hong KS

  • Lab Med Online.
  • 2018 Oct;8(4):135-139.
  • doi: 10.3343/lmo.2018.8.4.135
BACKGROUND: The point-of-care (POC) troponin T assay has been used in various clinical settings. Recently, a POC troponin T assay with an extended measurable range (40 ng/L-2,000 ng/L) was introduced....
Clinical Usefulness of Direct/Total Bilirubin Ratio

Hur K, Park IK

  • Lab Med Online.
  • 2018 Oct;8(4):127-134.
  • doi: 10.3343/lmo.2018.8.4.127
BACKGROUND: The direct/total (d/t) bilirubin ratio can be used to distinguish the causes of jaundice in many patients who have increased levels of direct and indirect bilirubin. However, the reference...

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