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A Case of Bone Marrow Necrosis in B-Acute Lymphoblastic Leukemia with Philadelphia Chromosome at Presentation

Jeong IH, An GD, Lim HH, Woo KS, Kim KH, Kim JM, Lee JH, Han JY

Bone marrow necrosis (BMN) is a pathologic state which is derived from various disease entities. Most commonly, it is accompanied by hematologic malignancies such as acute leukemia. The patients with...
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Primary Myelofibrosis with MPL S505N Mutation: The First Case Reported in Korea

Kim UJ, Lee HJ, Choi IS, Kang SH, Jang SJ, Moon DS, Park G

MPL mutation is an important molecular marker in myeloproliferative neoplasms (MPN). Although MPL W515 is a hot spot for missense mutations in MPN, MPL S505 mutations have been reported in...
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Germline Variants in MLH1, MSH2, and MSH6 in Korean Patients with Lynch Syndrome

Park KJ, Chang DK, Kim HC, Kim JW

BACKGROUND: The phenotypic and genetic spectrum of Lynch syndrome (LS) seems to differ according to ethnicity. The aim of this study was to investigate the clinical, pathological, and genetic features...
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Genetic Screening for Chromosomal Abnormalities and Y Chromosome Microdeletions in 846 Infertile Korean Men

Han SH, Bak CW, Cho H, Ban GW, Kang JS, Lim HS, Lee KR, Hwang SY

BACKGROUND: Chromosomal abnormalities are confirmed as one of the frequent causes of male infertility. The microdeletion of the azoospermia factor (AZF) region in the Y chromosome was discovered as another...
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Clinical Usefulness of ImmuneCheckâ„¢ IgG for Rapid Semiquantitation of Total IgG

Choi J, Lee SC, Park KH, Yoon H, Kim HS, Park JW

BACKGROUND: Conventional IgG assays require costly equipment and skilled experts. Semiquantitative measurement of total IgG using point-of-care testing devices may be the solution for these limitations. This study evaluated the...
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Performance Evaluation of the Point-of-Care Cardiac Troponin T Assay

Kim YH, Jeong TD, Hong KS

BACKGROUND: The point-of-care (POC) troponin T assay has been used in various clinical settings. Recently, a POC troponin T assay with an extended measurable range (40 ng/L-2,000 ng/L) was introduced....
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Clinical Usefulness of Direct/Total Bilirubin Ratio

Hur K, Park IK

BACKGROUND: The direct/total (d/t) bilirubin ratio can be used to distinguish the causes of jaundice in many patients who have increased levels of direct and indirect bilirubin. However, the reference...
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