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10 results

Plasma Cell Myeloma in a Patient with Chronic Myelogenous Leukemia

Lee JH, Kim YK

  • Lab Med Online.
  • 2017 Jan;7(1):49-51.
  • doi: 10.3343/lmo.2017.7.1.49
No abstract available.
Whole Exome Sequencing in a Korean Child with Joubert Syndrome-related Disorders

Lee JH, Oh IK, Yoon MJ, Yoon KH

  • Lab Med Online.
  • 2017 Jan;7(1):45-48.
  • doi: 10.3343/lmo.2017.7.1.45
Joubert syndrome and Joubert syndrome-related disorders (JSRDs) are rare autosomal recessive or X-linked disorders characterized by cerebellar vermis hypoplasia and a brain stem malformation, which presents as the “molar tooth...
A Korean Patient with Early Juvenile Form of Metachromatic Leukodystrophy: Biochemical and Molecular Genetic Investigation

Kim YB, Park HD, Choi R, Lee SY, Ki CS, Song J, Kim JW, Lee J

  • Lab Med Online.
  • 2017 Jan;7(1):41-44.
  • doi: 10.3343/lmo.2017.7.1.41
Metachromatic leukodystrophy is an inherited lysosomal storage disorder caused by the deficiency of arylsulfatase A activity. The patient in this study, a 5-yr-old girl, presented with progressive psychomotor regression. An...
Case of Bile Canalicular Antibody in a Korean Patient with Alcoholic Hepatitis

Kim SH, Jearn LH, Kim TY, Choi HS

  • Lab Med Online.
  • 2017 Jan;7(1):37-40.
  • doi: 10.3343/lmo.2017.7.1.37
Bile canalicular antibody (BCA) was first reported in 1969. Many studies of BCA were performed in the 1970s and 1980s and revealed that BCA has a highly positive rate in...
Eosinophilic Meningitis after Bovine Graft Duraplasty for Arnold-Chiari Malformation Type 1 in a 33-year-old Man

Lee HT, Park PW, Seo YH, Kim KH, Seo JY, Jeong JH, Kim MJ, Ahn JY

  • Lab Med Online.
  • 2017 Jan;7(1):34-36.
  • doi: 10.3343/lmo.2017.7.1.34
Cases of pediatric eosinophilic meningitis following duraplasty with a bovine graft have been reported. These patients recovered following the surgical removal of the dural graft or steroid therapy. Decompression for...
Prognostic Implications of Elevated Cardiac Troponin T in Patients with Acute Ischemic Stroke

Jung CL, Jeong TD, Hong KS

  • Lab Med Online.
  • 2017 Jan;7(1):28-33.
  • doi: 10.3343/lmo.2017.7.1.28
BACKGROUND: Elevated cardiac troponin T (cTnT) levels have been reported in patients with acute ischemic stroke, however, the prognostic relevance is not well established. We evaluated the association between cTnT...
Performance Evaluation of Cartridge-Type Blood Gas Analyzer: i-Smart 300

Yi A, Kim H, Moon HW, Hur M, Yun YM

  • Lab Med Online.
  • 2017 Jan;7(1):20-27.
  • doi: 10.3343/lmo.2017.7.1.20
BACKGROUND: Blood gas analysis plays a crucial role in critical care settings, and immediate and precise analysis improves clinical outcomes through prompt treatment. We evaluated the performance of a cartridge-type...
Fragment Analysis for Detection of the FLT3-Internal Tandem Duplication: Comparison with Conventional PCR and Sanger Sequencing

Lee G, Kim J, Lee S, Jang W, Park J, Chae H, Kim M, Kim Y

  • Lab Med Online.
  • 2017 Jan;7(1):13-19.
  • doi: 10.3343/lmo.2017.7.1.13
BACKGROUND: We evaluated a sensitive and quantitative method utilizing fragment analysis of the fms-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD), simultaneously measuring mutant allele burden and length, and verified the...
The Usefulness of Hematological Parameters for Assessing Disease Progression in Patients with HIV Infection

Kim HJ, Park Y, Koo SH, Kwon GC, Kim YS, Sohn KM, Kim J

  • Lab Med Online.
  • 2017 Jan;7(1):7-12.
  • doi: 10.3343/lmo.2017.7.1.7
BACKGROUND: In patients with HIV, CD4+ T cell count and viral load are the main laboratory tests performed to assess clinical management. However, they require extensive resources. In this study,...
Guidelines for the Performance Evaluation of In-Vitro Diagnostic Test for the Detection of Norovirus Infection in Korea

Kim J, Kim HS, Lee S, Oh SH, Woo KS, Kim SY, Min EK

  • Lab Med Online.
  • 2017 Jan;7(1):1-6.
  • doi: 10.3343/lmo.2017.7.1.1
Norovirus is a leading cause of epidemic and sporadic acute gastroenteritis worldwide. Rapid and accurate detection of norovirus is essential for the prevention and control of norovirus outbreaks. The purpose...

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