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Beyond Diagnostic Accuracy: The Clinical Utility of Diagnostic Tests

Bossuyt PM, Reitsma JB, Linnet K, Moons KG

  • Lab Med Online.
  • 2013 Oct;3(4):269-276.
Like any other medical technology or intervention, diagnostic tests should be thoroughly evaluated before their introduction into daily practice. Increasingly, decision makers, physicians, and other users of diagnostic tests request...
Occurrence of a PCR-Positive but Culture-Negative Case for vanB Vancomycin-Resistant Enterococci in Stool Surveillance

Won D, Hong KH, Yun K, Sung H, Kim MN

  • Lab Med Online.
  • 2013 Oct;3(4):264-268.
We present here occurence of PCR-positive but culture-negative for vanB vancomycin-resistant enterococci (VRE) from an enrichment broth of a stool surveillance culture in a patient suffering from Parkinson's disease, who...
A Case of Platelet Satellitism with Platelet Phagocytosis by Neutrophils and Platelet-neutrophil Agglutination

Yoon KH

  • Lab Med Online.
  • 2013 Oct;3(4):259-263.
Platelet satellitism is a rare phenomenon in which platelets adhere to the surface of neutrophils; in addition, platelet phagocytosis by neutrophils and monocytes is rare event. Although its clinical significance...
Methods for Flow Cytometric Analysis of T Cell Subsets in HIV-infected Patients: 2-Color versus 4-Color

Ahn S, Kang SJ, Lim YA, Lee WG, Cho SR

  • Lab Med Online.
  • 2013 Oct;3(4):253-258.
BACKGROUND: Blood CD4+ T-lymphocyte (T4) count is a major clinical marker for the diagnosis and management of AIDS, and flow cytometry is considered the gold standard for T4 enumeration. Our...
Evaluation of the Performance of an Adiponectin ELISA-based Test and Establishing Serum Adiponectin Reference Intervals for Korean Population

Park Y, Kim YR, Kim HS

  • Lab Med Online.
  • 2013 Oct;3(4):242-252.
BACKGROUND: Adiponectin is a plasma protein secreted by adipose tissues and low serum adiponectin concentration has been reported to be associated with insulin resistance and metabolic syndrome (MS). We evaluated...
Comparative Evaluation of the HPV28 Detection and HPV DNA Chip Test for Detecting and Genotyping Human Papillomaviruses

Shin E, Bae H, Song WK, Jung SK, Hwang YS

  • Lab Med Online.
  • 2013 Oct;3(4):234-241.
BACKGROUND: The HPV28 Detection test (Seegene) is a real-time polymerase chain reaction assay that is designed for testing a total of 28 human papillomavirus (HPV) genotypes and estimating the approximate...
Evaluation of ExiPrep16 Automated System for the Extraction of Nucleic Acids from Nasopharyngeal Swabs for the Detection of Respiratory Viruses

Lee KS, Park DS, Yoon KH, Lee YJ, Cho JH

  • Lab Med Online.
  • 2013 Oct;3(4):227-233.
BACKGROUND: Automated nucleic acid extraction offers a standardized sample treatment method, low error rate, and avoids sample nucleic acid contamination for use in molecular diagnostics. Here, we evaluated the performance...
Performance Evaluation of the CAPILLARYS 2 FLEX Piercing Analyzer for HbA1c Determination

Jeon Y, Han M, Lee K, Chang HE, Park KU, Song J

  • Lab Med Online.
  • 2013 Oct;3(4):221-226.
BACKGROUND: The hemoglobin A1c (HbA1c) level is widely used to monitor glycemic control in diabetes mellitus patients, and various methods are used for its determination. The CAPILLARYS 2 FLEX Piercing...
Association of Blood Homocysteine levels with Subclinical Atherosclerosis in Impaired Fasting Glucose

Nah EH, Cho HI

  • Lab Med Online.
  • 2013 Oct;3(4):213-220.
BACKGROUND: Prediabetes is the condition associated with the development of type 2 diabetes and a risk of cardiovascular disease. Abnormal homocysteine levels have been found to be associated with atherosclerosis...
Analytical Performance of Wako and Sekisui Clinical Chemistry Assays on Hitachi LABOSPECT 008

Chae H, Park HI, Kim M, Lee J, Kim Y

  • Lab Med Online.
  • 2013 Oct;3(4):198-212.
BACKGROUND: We evaluated the analytical performance of Wako assays for albumin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN), complement C3 and C4, calcium, creatine kinase (CK), C-reactive...
Basic Data for Reference Intervals in Koreans for Parameters Produced by Multiplate Platelet Function Analyzer

Baik SY, Hong JM, Lim YA

  • Lab Med Online.
  • 2013 Oct;3(4):191-197.
BACKGROUND: The Multiplate analyzer (Dynabyte GmbH) has been recently introduced as a platelet function test for patients taking antiplatelet drugs. The study aimed at providing basic data for determining the...

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