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A Case of Atypical Chronic Myeloid Leukemia with the JAK2V617F Mutation

Kim JY, Lee SR, Nam MH, Yoon SY, Lim CS, Lee CK, Kim BS, Cho Y, Kim YK, Lee KN

Atypical chronic myeloid leukemia (aCML) is a rare leukemic disorder that shows myelodysplastic and myeloproliferative features simultaneously. The Janus kinase 2 gene V617F mutation (JAK2V617F) in aCML has been the...
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A Case of Therapy-related Myeloid Neoplasm after Successful Treatment of Acute Promyelocytic Leukemia

Kwon A, Park JY, Kwon JH, Song HH, Shin KS, Lee YK, Cho HC

Acute promyelocytic leukemia (APL) is considered as a curative disease after combined chemotherapy based on all-trans retinoic acid (ATRA) and anthracycline. However, as long-term survivors continue to increase, reports on...
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Comparison of Culture, Direct Immunofluorescence Assay, and Multiplex Reverse Transcriptase PCR for Detection of Respiratory Viruses

Yoon KH, Cho JH

BACKGROUND: Rapid detection of causative viruses is important for the management of acute respiratory illnesses. To increase the detection rate and decrease the turnaround time (TAT) and cost, we used...
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In Vitro Activities of Ceftriaxone-Sulbactam against Major Aerobic and Anaerobic Bacteria from Clinical Samples

Cho S, Chung HS, Lee Y, Kim M, Yong D, Jeong SH, Lee K, Chong Y

BACKGROUND: beta-lactam antibiotics are one of the most common antimicrobial agents. However, the increasing of beta-lactamase-producing bacteria makes these agents less useful. Therefore, agents stable for beta-lactamase have been developed....
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Analysis of TP53 Gene Mutations in the Korean Patients with Lung Cancer

Jung SB, Chang HK, Choi SC, Shin KC, Lee KH, Jeon CH

BACKGROUND: Lung cancer is one of the leading causes of cancer-related deaths throughout the world. The gene tumor protein 53 (TP53) is frequently mutated in cases of lung cancer. This...
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Analysis of Immunoglobulin Gene Rearrangement: Comparison between BIOMED-2 Multiplex PCR and Conventional Nested PCR

Sung JY, Kang SY, Kim SH, Kwon JE, Ko YH

BACKGROUND: Immunoglobulin (Ig) gene rearrangement analysis is a useful additional tool to detect clonality of B-lymphoproliferative disease and the method to detect immunoglobulin gene rearrangement is required the high sensitivity...
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Seroprevalence of Toxoplasmosis in Pregnant Women in Daejeon, Korea

Ko YH, Lee M, Shin SY, Koo SH, Song JH, Lim J, Kwon KC

BACKGROUND: Toxoplasma gondii can cause devastating disease in the fetus and newborn infant. Serologic testing of pregnant women for Toxoplasma-specific antibodies can be used to identify those women at risk...
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Evaluation of Rapid Antigen Test for the Detection of Norovirus Infection: Comparison with ELISA and Real Time Quantitative Reverse Transcription PCR Assays

Kim HS, Kim KH, Kwon HW, Kang TY, Hur M, Kim HS, Kim JS, Song W, Kang HJ, Lee KM

BACKGROUND: Norovirus is a leading cause of epidemic and sporadic acute gastroenteritis worldwide. Because of the rapid transmission of the virus, early detection is important to prevent outbreak of norovirus...
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Creatinine Determination by Nova CCX Analyzer Harmonized with the Roche Enzymatic Method for Early and Accurate Detection of Renal Dysfunction

Kim HS, Park H, Chung S, Kim JH

BACKGROUND: Early detection of underlying renal dysfunction among emergency patients is important, particularly before imaging studies using contrast media. The estimated glomerular filtration rate (eGFR) calculated from creatinine values is...
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Translation: Executive Summary: Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus

Sacks DB, Arnold M, Bakris GL, Bruns DE, Horvath AR, Kirkman MS, Lernmark A, Metzger BE, Nathan DM

BACKGROUND: Multiple laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. APPROACH:...
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